13 results about "Cyclodecane" patented technology

A tricyclodecanedimethanol composition is provided. Applications using the above tricyclodecanedimethanol composition are also described. [Solution] A tricyclodecanedimethanol composition comprising tricyclodecanedimethanol, wherein the 173° backscatter intensity T1 measured at a temperature of 25°C using a dynamic light scattering measurement method of the tricyclodecanedimethanol composition is equal to that of a standard sample (D 50 A tricyclodecanedimethanol composition that satisfies the following condition: when the backscattering intensity of a 0.002 volume% aqueous suspension of latex with a wavelength of 300 nm is T2, T2÷8.0 ≤ T1 ≤ T2×5.0.

The present application relates to a process for the synthesis of diazabicyclo [6.2. 0] decane related compounds. The invention provides a method for synthesizing a diazabicyclo [6.2. 0] decane compound. The synthesis is carried out by stereoselectively synthesizing chiral lactone and then forming azetidine through a series of chemical selective reactions. According to the invention, diazabicyclo [6.2. 0] decane related compounds are formed by means of double cyclization.

The invention discloses sodium sulfosuccinate containing dihydric alcohol tricyclodecane dimethyl carbinol and a preparation method of the sodium sulfosuccinate. The preparation method comprises the following steps: sequentially adding a solvent, dihydric alcohol tricyclodecane dimethyl carbinol or alkoxide thereof, maleic anhydride and a catalyst into a reactor, heating to 50-100 DEG C under the protection of nitrogen, and stirring to react for 3-5 hours to obtain a dimaleate intermediate of dihydric alcohol tricyclodecane dimethyl carbinol or alkoxide thereof; and adding 20-40% of a sodium sulfite aqueous solution at the temperature of 80-100 DEG C under the protection of nitrogen, and reacting for 4-10 hours to obtain the sulfosuccinate salt containing the dihydric alcohol tricyclodecane dimethyl carbinol. The novel sodium sulfodisuccinate containing the dihydric alcohol tricyclodecane dimethyl carbinol is prepared by taking the dihydric alcohol tricyclodecane dimethyl carbinol as a raw material, and when the novel sodium sulfodisuccinate containing the dihydric alcohol tricyclodecane dimethyl carbinol is used as Gemini type sulfosuccinate, the novel sodium sulfodisuccinate containing the dihydric alcohol tricyclodecane dimethyl carbinol shows excellent performance and has very good application prospects.

The present invention relates to novel pyrrolidine-fused myrtanol derivatives (or 4-azatricyclo[6.1.1.02,6]decanes) of the general formula (I) or pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions comprising such compounds as well as their use as medicaments, especially in methods for the prophylaxis or treatment of a disease and / or a disorder caused by and / or associated with indolamine 2,3-dioxygenase 1 (1001) selected from: an inflammatory condition, an infectious disease, a cancer, a central nervous system disease or disorder, a disease or disorder relating to female reproductive health, coronary heart disease, chronic renal failure, post anaesthesia cognitive dysfunction, and cataracts.

The invention relates to the technical field of coatings, in particular to a photocuring hub coating and a preparation method thereof. The invention overcomes the problems of low yield and poor aging resistance of photocureable coatings in the prior art. The preparation method comprises the following steps: preparing modified acrylic resin by taking isophorone diisocyanate, tricyclodecane dimethyl carbinol, trimethylolpropane, fluorine-containing alcohol and hydroxyethyl acrylate as raw materials; dispersing the silane modified nano aluminum oxide into a monomer to prepare a dispersed filler; the modified acrylic resin, the dispersed filler, the reactive diluent, the sulfhydryl compound, the initiator and the like are compounded to prepare an acrylic coating; and finally, carrying out infrared leveling and UV-LED and mercury lamp segmented curing film forming to obtain the photocuring wheel hub coating. According to the invention, a tricyclodecane rigid framework is introduced and is matched with a segmented curing process, so that the problem of low yield of the coating is solved; and meanwhile, by utilizing the surface migration characteristic of the fluorine-containing chain segment and nano inorganic enhancement, the aging resistance of the coating is remarkably improved.

The present application provides a method for synthesizing diazabicyclo[6.2.0]decane compounds. The synthesis proceeds through the stereoselective synthesis of a chiral lactone, followed by a series of chemoselective reactions to form an azetidine. The diazabicyclo[6.2.0]decane related compounds are formed by a bi-cyclization.

The invention discloses a process route for synthesizing 4-[4-(1, 1-dimethylethyl) phenyl]-1, 4-oxothiaonium salt and 1-(5, 5, 6, 6-tetrafluorospiro [1, 3-dioxane naphthene-2, 2 '-tricyclo [3.3. 1.13, 7] decane]-5'-yl) 2, 2-difluoro-2-sulfoacetate, cation fragments are provided by bis (4-tert-butylphenyl) iodine trifluoromethanesulfonate, and the cation fragments are provided by bis (4-tert-butylphenyl) iodine trifluoromethanesulfonate. According to the synthetic route, thioxane sulfonate is formed through substitution, then ion exchange is carried out, and finally the obtained intermediate is subjected to ketal to obtain the target photoacid generator product. By optimizing reaction conditions and a process route, the use amount of resin is reduced, side reactions are effectively controlled in the front stage of the process, the purity, stability and yield of the photoacid generator are improved, the metal content and halogen content of the compounds are reduced, and the yield of the photoacid generator is improved. The requirements of modern microelectronic manufacturing on a high-performance photoacid generator are met.

Providing a crystalline form that is stable in the pharmaceutical use environment of a prodrug compound of an amino acid derivative. 【Solution】A crystal of (1R,2R,3R,5R,6R)-2-amino-6-fluoro-3-[(4-fluorophenyl)methoxy]-2-({(1S)-1-[(tricyclo[3.3.1.1 3,7 decane-1-carbonyl)oxy]ethoxy}carbonyl)bicyclo[3.1.0]hexane-6-carboxylic acid having at least one of the physical properties (a) to (c) below. (a) Having peaks at 2θ = 10.8°, 14.5°, 19.4°, and 21.8° in powder X-ray diffraction (Cu-Kα); (b) In the infrared absorption spectrum (ATR method), characteristic absorption bands are at 3310 cm -1 , 1762 cm -1 , 1731 cm -1 , 1583 cm -1 and 1236 cm -1 ; or (c) In differential thermal analysis / thermogravimetry (TG / DTA), an endothermic peak is at 225 - 235 °C.

A tricyclodecane dimethanol composition containing a chiral compound A in which one of enantiomeric forms is represented by the following formula (I), a chiral compound B in which one of enantiomeric forms is represented by the following formula (II), a chiral compound C in which one of enantiomeric forms is represented by the following formula (III), and a chiral compound D in which one of enantiomeric forms is represented by the following formula (IV), the number of moles Xa of the chiral compound A, the number of moles Xb of the chiral compound B, and the total number of moles Xt of the number of moles of the chiral compound A, the chiral compound B, the chiral compound C, and the chiral compound D determined by nuclear magnetic resonance spectroscopy satisfy Xa / Xt ≤ 0.430 and Xb / Xt ≥ 0.016.

The invention relates to the technical field of acrylic resin composite materials, and particularly discloses self-healing thermosetting acrylic resin which comprises the following components in parts by weight: 60-80 parts of an acrylic monomer, 10-18 parts of a dynamic cross-linking agent and 2.6-6 parts of a functional aid, the acrylic acid monomer is selected from one or more of methyl methacrylate, isobornyl methacrylate, tricyclodecane dimethyl alcohol diacrylate, diethylene glycol dimethacrylate, 3-methyl-1, 5 pentanediol diacrylate and neopentyl glycol dimethacrylate; the dynamic cross-linking agent is prepared from bis (2-methacryloyloxyethyl) disulfide and 4-maleimido phenol according to the weight ratio of 1 to (0.5 to 2.5). The self-healing thermosetting acrylic resin provided by the invention has high mechanical strength, efficient self-healing under mild conditions and excellent weather resistance, and has good application prospects in the fields of photovoltaic module packaging coatings, electronic device protection adhesives and the like.

A tricyclodecane dimethanol composition comprising tricyclodecane dimethanols, wherein the tricyclodecane dimethanols comprise a chiral compound A, one of whose enantiomers represented by the following formula (I), a chiral compound B, one of whose enantiomers represented by the following formula (II), and a chiral compound C, one of whose enantiomers represented by the following formula (III), and a peak area Xc of the chiral compound C in a gas chromatogram and a total peak areas Xt of tricyclodecane dimethanols in a gas chromatogram, which are detected by a gas chromatography, satisfy Xc / Xt≥0.35.

The invention provides a 1, 8-TBD bidentate silylene ligand, a 1, 8-TBD bidentate silylene iron complex as well as a preparation method and application thereof, and belongs to the technical field of coordination chemistry and transition metal. The preparation method comprises the following steps: designing and synthesizing a bis-silylene ligand taking 1, 8, 10-triazol-9-boron-bicyclo [4.4. 0] decane as a framework, and carrying out complex reaction on the bis-silylene ligand and iron salt to obtain the iron complex. The iron complex can efficiently catalyze a hydrogen-deuterium exchange reaction of a pyridine substrate in the presence of an additive, so that perdeuteration of pyridine is realized, and various deuterated compounds with application value are generated. The iron-based catalyst has excellent deuteration efficiency, shows excellent activity, especially has deuteration efficiency obviously superior to that of the existing iron-based catalyst when being used for treating pyridine substrates with certain steric hindrance, and has a good application prospect.

A tricyclodecane dimethanol composition containing a chiral compound A in which one of enantiomeric forms is represented by the following formula (I), a chiral compound B in which one of enantiomeric forms is represented by the following formula (II), a chiral compound C in which one of enantiomeric forms is represented by the following formula (III), and a chiral compound D in which one of enantiomeric forms is represented by the following formula (IV), the number of moles Xa of the chiral compound A, the number of moles Xb of the chiral compound B, and the total number of moles Xt of the number of moles of the chiral compound A, the chiral compound B, the chiral compound C, and the chiral compound D determined by nuclear magnetic resonance spectroscopy satisfy Xa / Xt ≤ 0.430 and Xb / Xt ≥ 0.016.