469 results about "Cyclopentanes" patented technology

The invention discloses a low-thermal-conductivity rigid polyurethane foam taking cyclopentane as a main body and a manufacturing method and applications thereof. The invention relates to the technical field of rigid polyurethane foams, and specifically relates to a rigid polyurethane foam which is prepared from the following raw materials in parts by weight through a hybrid reaction: 135-165 parts of polyisocyanate, 100 parts of polyol composition, 10-16 parts of cyclopentane, 1.8-2.3 parts of catalyst, 1.8-2.5 parts of silicone oil, 1.6-2.4 parts of water, and 1-chlorine-3,3,3-trifluoropropene with a weight accounting for 1-3% of the total weight of the raw materials. The invention also relates to a preparation method of the rigid polyurethane foam and the application of the rigid polyurethane foam in refrigerator and freezer industries. Cells of the rigid polyurethane foam disclosed by the invention are smaller and more uniform, so that the thermal conductivity (minimum: below 0.01800 W/m.K) is greatly reduced, and the strength of the foam is increased; the rigid polyurethane foam reduces the energy consumption and is good in environmental friendliness; the rigid polyurethane foam disclosed by the invention has a positive role in promoting the upgrading and updating of an existing cyclopentane foaming technology for refrigerators.

The present invention provides a hemoglobin molecule (Hb) having six±one PEG chains, wherein two of said PEG chains are bound to Cys-93 (β) of Hb, and the remaining PEG chains are bound to thiol groups introduced on ε-NH₂ of Hb. The present invention also provides a process for preparing a modified hemoglobin molecule (Hb), comprising the steps of: (a) reacting Hb with 8-15 fold excess of iminothiolane to form thiolated Hb; and (b) reacting the thiolated Hb with 16-30 fold excess of PEG functionalized with a maleimide moiety, to form the modified Hb.

The present invention relates to a novel fluorine-containing cyclic compound that is derived from a norbornadiene and hexafluoroacetone and has an oxacyclopentane or oxacyclobutane structure. This compound may be represented by the following formula (1) or (2). Furthermore, the present invention relates to a fluorine-containing high-molecular compound prepared by a polymerization or copolymerization using this fluorine-containing cyclic compound or its derivative. By using such fluorine-containing high-molecular compound, it is possible to provide a superior resist material and a fine pattern forming process using the same.

A polymer containing units of fluorene, anthracene and benzothiadiazole with the following formula is provided:

2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)-9,9-dialkylfluorene, 9,10-dibromoanthracene or its or derivatives and 4,7-bis(5′-bromo-2′-thienyl)-2,1,3-benzothiadiazole or its derivatives are added to solvent, after the catalyst and base solution are added to the solution, the compounds in the solution are processed by Suzuki coupling reaction to obtain polymer. This kind of polymer containing units of fluorene, anthracene and benzothiadiazole have low energy gap, high mobility of the carriers, wide range of spectral absorption and have a broad prospect of application in the field of photoelectric.

The invention relates to low-density and low-heat-conduction-rate polyurethane foam and a preparation method thereof. The polyurethane foam is prepared from the following raw materials in parts by weight: 100 parts of a polyatomic alcohol composition, 1 to 30 parts of a low-gas-phase heat conductivity coefficient foaming agent, 0.5 to 6 parts of HFC-134a, 5 to 20 parts of pentane, 0.5 to 3.0 parts of water, 1.0 to 3.5 parts of a catalyst and 1.0 to 4.0 parts of a foam stabilizer, wherein the ratio of the use amount of organic polyisocyanate to the total mass of the raw materials is 1.15 to 1.35. The polyurethane foam prepared by the method has a low GWP value; when the polyurethane foam is used, gas which damages an ozone layer is not released; the molding density of the foam is low and is reduced by 19 percent or more when being compared with that of a common cyclopentane system; the polyurethane foam is good in dimensional stability and low in heat conduction coefficient; the total weight of a product can be reduced and the comprehensive cost is low; the polyurethane foam has extremely good economic benefits in a heat preservation industry of high-end products.

The invention discloses a hard polyurethane foam for ultralow-temperature insulation, which is prepared by independently foaming trans-1,3,3,3-tetrafluoropropylene or foaming the trans-1,3,3,3-tetrafluoropropylene with cyclopentane. By utilizing the characteristic that HFO-1234ze has higher steam pressure at low temperature, the polyurethane foam has favorable dimensional stability at ultralow temperature, and is applicable to the field of ultralow-temperature insulation. The hard polyurethane foam for ultralow-temperature insulation is prepared by mixing composite polyethers and poly MDI (methylenediphenyl diisocyanate) in a mass ratio of 1:(1.1-1.3), wherein the composite polyethers contain a physical foaming agent and a chemical foaming agent; the physical foaming agent is HFO-1234ze or an HFO-1234ze-cyclopentane mixture; and the chemical foaming agent is water.

This invention relates to methyl alcohol diesel oil and its additive, in which, the additive is prepared in the volume ratio of the following raw materials: MTBE 10-15%, normal actane 5-10%, isopropyl acetone 15-20%, n-butyl alcohol 25-30% and methyl cyclopentane 10-35%, and said methyl alcohol is prepared in the volume ratio of the following materials: methyl alcohol 10-25%, diesel oil 70-88% and its additive 2-5%, which solves the technical problems of causticity, swellingness, difficulty of cold starting up, hot air-blocking, separation when meeting water, power reduction, fluidity and emulsification met when using the present methyl acohol.

Provided is an azole derivative which can be contained as an active ingredient in an agricultural or horticultural chemical agent having an excellent disease control effect. This azole derivative is represented by general formula (I). (In formula (I), R1 represents a C1-C6 alkyl group which may be substituted; R2 represents a functional group containing a carbonyl group, wherein a carbon atom in the carbonyl group is bonded to both a carbon atom substituted by R1 in the cyclopentane ring and any one selected from a hydrogen atom, a hydroxyl group, R3, OR3 and NR3R4; R3 and R4 independently represent a C1-C6 alkyl group, a C2-C6 alkenyl group or a C2-C6 alkynyl group; Y represents a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C1-C4 alkoxy group, a C1-C4 haloalkoxy group, a phenyl group, a cyano group or a nitro group; m represents 0-5; and A represents a nitrogen atom or a methine group.).

A compound comprising

or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed.

Also disclosed herein are compounds comprising

or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.

The invention relates to a safe solution spinning method. The method is characterized in that in the solution spinning process, the oxygen content of mixed gas in a spinning box is controlled to be below 18vol%. By means of the method for introducing incombustible gas into the spinning box to reduce the oxygen content, the explosion risk in the solution spinning process is avoided, and the production safety is improved. The requirement for solvents can be reduced, the selection range of the solvents in the solution spinning process can be wider, the solvents are not limited to hydrocarbon solvents containing halogen, and hydrocarbon solvents (such as cyclopentane and cyclohexane) which have low flash points and only contain carbon atoms and hydrogen atoms can be adopted. In addition, by arranging a VOC-rich tail gas treatment system 8, the content of organic compounds in VOC-rich tail gas can be effectively reduced, and therefore low-VOC nitrogen is obtained, the tail gas in the spinning box can be recycled, and the production cost is reduced.

The invention discloses a modified cardanol-based polyether polyol and high-fire-resistant hard polyurethane foam prepared by the modified cardanol-based polyether polyol and a preparation method thereof. The polyether polyol takes cardanol, paraformaldehyde, diethanolamine, diethylenetriamine, tribromoaniline, melamine, oxirane and epoxypropane as raw materials, the raw materials are reacted for synthesis of cardanol Mannich polyether polyol, a hydroxyl value is 200-700mg/gKOH, the moisture is less than or equal to 1.0%, the viscosity is 1000-12000 mPa.s (at 25 DEG C), and the cardanol-based polyether polyol can be taken as a polyhydric alcohol component which can be used in the hard polyurethane foam. The product has advantage of adjustable functionality, contains a flame-retardant group, and has good compatibility with a cyclopentane foaming agent.

The invention discloses a double-effect rectification method for finely separating hybrid pentane isomer, which comprises the following steps: introducing a crude pentane raw material into a condensation preheater, a dehydrogenation tower of which the top is connected with a condenser and a reflux tank and the bottom is connected with a reboiler, an isopentane tower, an n-pentane tower, an azeotrope tower and a cyclopentane tower in turn to be rectified and separated, feeding total vapor at the tower top of the isopentane tower into the n-pentane tower and the reboiler as heat sources thereof, condensing the vapor into a two-phase mixture of vapor and liquid after heat exchange, then feeding the mixture to the azeotrope tower and the reboiler to exchange heat, re-preheating the crude pentane raw material by the waste heat after heat exchange, and finally beating the liquid to the isopentane tower as reflux liquid by a reflux pump of the isopentane tower. The method has the advantages of high product purity and low energy consumption and water consumption; and the product can be flexibly controlled according to the requirement.

The invention relates to a method for preparing a composite hydrate accelerant. The composite accelerant is characterized by being prepared by mixing cyclopentane or methyl cyclohexane serving as a kinetic accelerant and 2-butyl octyl sodium sulfate serving as a surfactant, wherein the percentage by mass of the cyclopentane or methyl cyclohexane in a solvent is 1.3 to 15.0, and the concentration of the surfactant 2-butyl octyl sodium sulfate in the solvent is 0.32*10<-3> to 9.5*10<-3> mol/L; and 0.02 to 0.78 mass percent of sodium chloride is added into the mixture. In the method, a high-pressure gas cylinder is taken as a gas source, a pressure is properly adjusted through a pressure adjustment valve, consumed gas is metered by a mass flow meter, a temperature and the pressure in a reactor are monitored by pressure and temperature transducers, and the temperature of liquid in a water tank is controlled by means of a thermostatic water bath, so that the temperature in the reactor is adjusted; and data is acquired by a data acquisition system and a computer, and the forming condition of a hydrate in the reactor is monitored by a photoelectric lens. The method for preparing the composite hydrate accelerant not only can reduce the forming condition of the hydrate, but also can shorten the formation time of the hydrate and improve the gas storage capacity of the hydrate.

The invention relates to a polyurethane rigid cellular plastic with improved property, which is prepared by the raw materials that are fully mixed in a high pressure foaming machine for reaction according to the ratio of parts by weight: composite polyether:mixed foaming agent:isocyanate = 100:7-27:110-150. The composite polyether is prepared by the components according to the ratio of parts by weight: composite polylols:foam stabilizer:catalyst:water:emulsifying agent= 100:1.0-4.0:0.5-5.0:0.5-3.5:0.5-10, wherein, the composite polylols comprise two or more polylols. Compared with cyclopentane foam and hydroflurocarbon foam, the heat conductivity coefficient of the foam prepared by the invention is obviously reduced; in the process of reaction between isocyanate and composite material, wider operating range can be obtained. The sensibility of the reaction towards parameters such as materials, mould, condition of circumstance and the like can be reduced.

The present invention relates to a polyether glycol for preparing fluorin-free rigid PU foam and a preparation method thereof. The invention obtains the polyether glycol, at the condition of mixing initiator and using KOH as a catalyst, by adding the mixture into the high-pressure reaction kettle, stirring to displace by the nitrogen, evacuating and dehydrating, controlling the temperature and the pressure of the kettle, dripping oxyalkylene continuously into the kettle until the hydroxyl value meets the need of polyether to ring-opening polymerize with oxyalkylene. The mixing initiator comprises, a) at least one active hydrogen compounds with the functionality more than 3; b) one active hydrogen compound with an aromatic ring structure or heterocycle structure; c) at least one active hydrogen compound with a functionality not more than 3 different from a) and b). The foam after foaming of the polyether by cyclopentane or full-water has an excellent high and low temperature dimensional stability and an excellent compressive strength, capable of replacing the traditional foaming process system and being used in the fields of refrigeratory, deep freezer, heat preservation of the underground conduit and the solar energy water heater, building materials, etc.

The invention discloses a preparation method of lamivudine and an intermediate thereof; (2R,5R)-5-hydroxyl-[1,3]oxathiolane-2-carboxylicacid(2S-isopropyl-5R-methyl-1R-cyclohexyl)ester, the structure of which is shown in formula (II) is used as a raw material; acyl compound, the structure of which is shown in formula (III) is obtained by the acylation reaction of acyl; acyl compound (III) reacts with cytimidine, the structure of which is shown in formula (IV) by condensation reaction to prepare the intermediate of lamivudine (V) and the intermediate is reducted to obtain lamivudine (I). The invention is characterized by safe and reliable operation, simplified process, low production cost and the like, thus being suitable for industrialized production.

The object of the present invention is to provide a production method wherein synthesis of a cyclic organic silicon compound similar to oxa-silacyclopentanes is completed in a single-step reaction. It is also to provide an organic silicon resin having an alcoholic hydroxyl group, which is capable of easily controlling its construction and is longitudinally stable.

The means for solving is to produce the cyclic organic silicon compound represented by the formula (3) below by reacting an olefin represented by the formula (1) below and an alkoxysilane represented by the formula (2) below in the presence of a catalyst comprising a transition metal.

(In the formula, Z is alkenyl group having carbon atoms from 2 to 5 where the terminal carbon atom forms a C═C bond, R is methyl group or hydrogen atom, and Me is methyl group.)

(In the formula, R₁ is alkyl group or alkoxyl group, having carbon atoms from 1 to 3, and R₂ is alkyl group having carbon atoms from 1 to 3.)

(In the formula, Z′ is alkylene group having carbon atoms from 2 to 5.) And it is an organic silicon resin having an alcoholic hydroxyl group obtained by performing hydrolysis and condensation of a cyclic organic silicon compound represented by the formula (3) above, or of a mixture of this and a polyfunctional alkoxysilane.

A method of preparing polyurethane or polyisocyanurate from compositions comprising reacting and foaming a mixture of at least one polyol and isocyanate which react to form polyurethane or polyisocyanurate foams in the presence of a blowing agents which comprises: a hydrofluorocarbon or at least one compound selected from the group consisting of: propane, n-butane, isobutene, n-pentane, isopentane, neopentane, cyclopentane, acetone, dimethyl ether, and inert gases; an acid; and, optionally, water.