The invention relates to a method for generating a
yeast core
promoter sequence based on a potential
diffusion model. The problems that in the prior art, a
promoter sequence generation method is unstable in training, the quality of generated samples is low, and the calculation cost is high are solved. The method comprises the following steps: S1, collecting and preprocessing data; s2, sequence coding; s3, constructing a potential
diffusion model; s4, performing model training; s5, generating a new
promoter sequence; and S6, comparing the generated sequence with an original
natural sequence. The method has the advantages that a potential
diffusion model based on
deep learning is trained by using an existing
saccharomycetes core promoter sequence
data set, so that the model learns and has the capability of generating a new
saccharomycetes core promoter, high-quality and diversified
saccharomycetes core promoter sequences are generated, and the defects that a traditional method is high in calculation cost and high in calculation efficiency are overcome. The generation speed is slow, and the quality of generated samples is poor. The biological experiment cost of the saccharomycetes promoter is reduced, the
research process is accelerated, and the
industrial fermentation optimization of the saccharomycetes is promoted.