36results about How to "Has immunomodulatory activity" patented technology

The invention relates to a moisturizing composition, and a preparation method and application thereof, which belong to the field of cosmetics. The moisturizing composition is prepared from the following components in parts by weight: 1.0 to 5.0 parts of sodium hyaluronate, 2.0 to 10.0 parts of carboxymethyl deacetyl chitosan, 30.0 to 60.0 parts of dendrobium officinale extract, and 25.0 to 67.0 parts of deionized water. The moisturizing composition can well form a netted natural biomimetic membrane with skin, the sodium hyaluronate performs the water supplementation and moisturizing in the biomimetic membrane, the carboxymethyl deacetyl chitosan forms a biomimetic sterile membrane, so that natural moisturizing factors such as the sodium hyaluronate can be effectively locked, the water loss rate is decreased; and the dendrobium officinale polysaccharide is combined with the natural biomimetic sterile membrane, so that the moisturizing lasting property after long-term use can be further improved, the restoration effect is improved, and the dryness and allergy problems of the skin can be fundamentally solved. The moisturizing composition has multidimensional efficacy such as moisturizing function, restoration function and skin barrier increasing function.

The invention discloses a method for producing giant salamander polypeptide powder liver protection capsules. The method comprises the following steps of: performing low-temperature drying, grinding, fat removal, controllable composite enzyme digestion, centrifugation, filtration, two-time membrane filtration, vacuum concentration, freeze drying and crushing on fresh giant salamander meat to obtain giant salamander polypeptide powder; encapsulating the giant salamander polypeptide powder, and packaging to obtain a finished product.

The invention discloses compound indigowoad root oral liquid for improving poultry immunity and a preparation method thereof and aims at providing compound indigowoad root oral liquid for improving organism immunity and increases vaccine immunity effect and a preparation method thereof. Each 100 liters of the oral liquid comprises the following components: 0.5 to 20kg of indigowoad root amylose, 0.5 to 20kg of astragalus amylose raw material medicament containing 50 percent of astragalus amylose, 0.5 to 10kg of epimedium amylose raw material medicament containing 50 percent of epimedium amylose, 0.5 to 10kg of morinda extract, 50g of potassium sorbate and the balance of injection water. In the method, an amylose component with immunologic enhancement effect is selected from an indigowoad root medicinal material and mixed with restorative Chinese medicaments with the same immunologic enhancement effect, such as astragalus, epimedium and morinda, to produce a synergetic effect to enhance treatment effect. The oral liquid has good treatment effect on low immunity of poultry caused by disease or breeding conditions and can strengthen immune effect of a vaccine.

The invention discloses an application of an antibacterial peptide C-BF in preparation of medicines for preventing and treating weanling stress of piglets. The intestinal morphology can be improved by the antibacterial peptide C-BF; the villus height can be increased; the intestinal inflammation is relieved; the growth performance of weaned pigs is improved; the diarrhea rate is lowered; and the antibacterial peptide C-BF is dosed through intraperitoneal injection.

The invention discloses natural antioxidant peptide Macrotympanain-Al and a preparation method and application thereof. The natural antioxidant peptide Macrotympanain-Al is a gene-encoded product, and a sequence from an N end to a C end is RLFKCYKPDS. The natural antioxidant peptide Macrotympanain-Al is prepared from skins of Odorrana graminea Boulenger which are typical in China, and in frog skins, the natural antioxidant peptide Macrotympanain-Al is mainly used for protecting exposed skins from being injured by ultraviolet rays; and the antioxidant polypeptide Macrotympanain-Al is applied to preparation of cosmetics. The natural antioxidant peptide Macrotympanain-Al returns to the origin, is purely natural, and accords with consumption requirements of common people at present. The activity of the natural antioxidant peptide Macrotympanain-Al is 1000 times stronger than that of the conventional antioxidant BHT (butylated hydroxytoluene). The natural antioxidant peptide Macrotympanain-Al not only has antioxidant activity, but also has a certain antibiotic activity, immunoregulation activity and the activity for inhibiting the formation of melanin.

The invention discloses a ganoderma lucidum spore powder wall polysaccharide, the ganoderma lucidum spore powder wall polysaccharide is glucan whose main chain is formed by four glycoside residues andbranch chains are formed by beta-D-Glcp-(1-> and beta-D-Glcp-(1->4)-beta-D-Glcp-(1->. The invention further discloses a preparation method of the ganoderma lucidum spore powder wall polysaccharide. In the ganoderma spores processed with the method, two kinds of beta-glucans with multiple branches can be obtained, the cellular level doesn't show immunization, unexpectedly, in various animal immunization model experiments, the polysaccharide has various immunoregulatory activities and is the main active ingredient in the ganoderma lucidum spore powder. Therefore, the ganoderma lucidum spore powder wall recycle application range is expanded greatly.

The invention relates to an application of lycium ruthenicum polysaccharides in preparation of immunoregulation medicines or health-care products. The lycium ruthenicum polysaccharides refer to a group of glycoprotein complex which have the molecular weight of 80-22kDa and are obtained by performing hot water extraction, ethanol precipitation, deproteinization and discoloring on lycium ruthenicum fruits. The animal experiments prove that the lycium ruthenicum polysaccharides have the effects of obviously improving the spleen and thymus indexes of immunosuppressed mice and improving the lymphocytes level of the immunosuppressed mice; the delayed type hypersensitivity of the immunosuppressed mice is enhanced; the antibody secreting level of the immunosuppressed mice is improved. The cell experiments prove that the spleen cell proliferation rate of the mice can be obviously improved through the lycium ruthenicum polysaccharides, macrophage cell lines RAW264.7 of the mice are promoted to secrete TNF (tumor necrosis factor)-alpha, NO and other immune factors, and the lycium ruthenicum polysaccharides are proved to have high immunological competences.

The invention relates to bean residue dietary fiber active peptide face-beautifying low-alcohol-content rice wine and a preparation method thereof. The rice wine is characterized by being prepared with, by weight, 200-300 parts of fresh bean residue, 30-35 parts of rice bran protein, 100-250 parts of rice wine, 5-7 parts of kudzu vine root extract, 3-5 parts of licorice extract, 5-7 parts of rose apple seed extract and 10-13 parts of perilla oil. Through the steps of drying, smashing, pickling, fermenting and enzymolyzing bean residue, beany flavor of the rice wine is reduced, and the rice wine is better in taste and more exquisite in quality and is fully utilized. A new drinking concept of seeking stimulus while pursing nutrition and health during drinking of people is met, a new nutrition absorbing concept of direct absorption is provided for people, improving of immunity is facilitated, and the rice wine has functions of resisting oxidation, lowering blood pressure and blood fat and protecting liver and is incomparable for any non-peptide wine.

The invention relates to a natural antioxidant peptide Tiannanin-beta1 and preparation method and application thereof. The natural antioxidant peptide Tiannanin-beta1 is a gene-encoding product and has the following sequence from the N-terminal to C-terminal: VVKFPYRCKAAF. The natural antioxidant peptide is prepared from the skin of Odorrana frogs which can only be found in China and exits in the frog skin to play a major role of protecting the exposed skin from ultraviolet injury. The antioxidant peptide Tiannanin-beta1 is applied to cosmetic production, is original and pure natural, and conforms to the consumption requirements for modern people. The activity of the antioxidant peptide is 1000 times higher than that of the conventional antioxidant BHT. Besides the antioxidant activity, the peptide Tiannanin-beta1 also has antimicrobial activity, immunoregulatory activity and melanin formation inhibitory activity.

The invention discloses germinated quinoa protein peptide meal replacement powder and a preparation method thereof. The germinated chenopodium quinoa is higher in protein content and more balanced in nutrition, and the protein active peptide of the germinated chenopodium quinoa obtained after enzymolysis can be combined with important sites of alpha-glucosidase through a hydrophobic reaction to inhibit generation of glucose in a body, so that intake of the glucose is controlled, and the activity of the protein active peptide of the germinated chenopodium quinoa is improved. And the konjak absorbs water to swell in small intestines after being taken, so that the absorption of saccharides is further hindered. The health-care tea not only has the advantages of being easy to brew, unique in taste, balanced in nutrition, low in fat, low in calorie and strong in satiety, but also has the effects of supplementing nutrition, reducing blood sugar and blood fat, regulating intestinal flora and the like, has a certain function of losing weight, and can meet the requirements of modern people and fast-paced life.

The invention discloses a preparation method of a dandelion root polysaccharide sulfation modified product and application of the dandelion root polysaccharide sulfation modified product. The polysaccharide content of the polysaccharide sulfation modified product is increased by 60% compared with the content before modification. The method comprises the following steps of: selecting an optimal extraction process through a plurality of groups of tests, obtaining crude polysaccharide by adopting a water extraction and alcohol precipitation method, deproteinizing by adopting a Sevag method, separating by adopting DEAE Sepharose Fast Flow, purifying by adopting sephadex to obtain dandelion root polysaccharide with high purity, and modifying by adopting a chlorosulfonic acid-dimethylformamide method to obtain a dandelion root polysaccharide sulfation modified product. According to the method, waste dandelion root resources are fully utilized, waste is turned into wealth, the dandelion root polysaccharide with immunoregulatory activity and the sulfated modified product of the dandelion root polysaccharide are obtained, and sustainable application of dandelion medicinal resources is achieved.

The invention discloses a natural antioxidant peptide (Rotodorin-D1) and a preparation method and application thereof. The natural antioxidant peptide (Rotodorin-D1) is a gene coded product, a sequence from an N end to a C end is KSSDVKYYLAKCTTDVQ. The natural antioxidant peptide (Rotodorin-D1) is made of skin of Odorrana graminea Boulenger which only exists in China; in Batrachia skin, Odorrana graminea Boulenger has a main role in protecting skin exposed to the outside from being damaged by ultraviolet rays, and the polypeptide (Rotodorin-D1) with antioxidative activity is used in preparation of cosmetics. Origin returning and all natural effects meet consuming requirements of current publics. Compared with the conventional antioxidant (BHT), the Rotodorin-D1 has activity which is improved by 1000 times; besides the antioxidant activity, the Rotodorin-D1 has certain antibacterial activity, immunoregulation activity, and melanin forming restraining activity.

The invention relates to a natural antioxidant polypeptide mixture and preparation method and application of the mixture. The natural antioxidant polypeptide mixture is prepared from the skin of Odorrana frogs which can only be found in China and exits in frog skin to protect the exposed skin from ultraviolet injury. The antioxidant polypeptide mixture is applied to the preparation of cosmetics. The antioxidant polypeptide mixture is original and pure natural and conforms to the consumption needs of modern people, and the activity of the antioxidant polypeptide mixture is 1000 times higher than that of the conventional antioxidant butylated hydroxytoluene (BHT). Besides the antioxidant activity, the polypeptide mixture also has antimicrobial, immunoregulatory and melanin formation inhibiting activities.

The invention relates to an active peptide preblend health-care rice wine capable of strengthening the spleen and stomach and a preparation method thereof. The invention is characterized in that the health-care rice wine is prepared from the following raw materials in parts by weight: 200-225 parts of fresh bean dreg, 30-35 parts of rice bran protein, 100-150 parts of rice wine, 5-7 parts of Chinese wolfberry extract, 5-7 parts of tuckahoe extract, 10-13 parts of Chinese yam powder and 3-5 parts of perilla. The bean dreg is dried, pulverized, pickled, fermented and subjected to enzymolysis and the like to reduce the beany flavor, and thus, has better mouthfeel and fine texture, thereby fully utilizing the bean dreg. The health-care rice wine satisfies the demands of people for excitement, nutrition and health, provides a new concept of directly absorbing nutrients for people, is beneficial to enhancing the immunologic function, has the functions of resisting oxidation, lowering the blood pressure and blood fat, protecting the liver and the like, and is incomparable with any other non-peptide wine.

The invention relates to a lung-moistening and beauty-maintaining bean dreg dietary fiber low-alcohol peptide wine and a preparation method thereof. The wine is characterized by being prepared from the following raw materials in parts by weight: 300-350 parts of fresh bean dregs, 30-35 parts of rice bran protein, 100-150 parts of rice wine, 15-20 parts of bitter gourd powder, 5-7 parts of tangerine peel micro powder, 30-35 parts of aloe juice, and 7-9 parts of black fungus polysaccharide. The active ingredients of the lung-moistening and beauty-maintaining bean dreg dietary fiber low-alcohol peptide wine provided by the invention have the health effects of clearing fire and moistening lung, improving the human immunity, disinfecting, diminishing inflammation, maintaining beauty and keeping young, and the like.