The invention discloses an ultraviolet-resistant children's clothing fabric and a manufacturing method thereof. The fabric comprises a cotton cloth layer, wherein one side of the cotton cloth layer isprovided with a first ultraviolet-resistant layer, one side, away from the first ultraviolet-resistant layer, of the cotton cloth layer is provided with a second ultraviolet-resistant layer, one side, away from the cotton cloth layer, of the first ultraviolet-resistant layer is provided with a reflective layer, one side, away from the cotton cloth layer, of the second ultraviolet-resistant layeris provided with a graphene layer, one side, away from the second ultraviolet-resistant layer, of the graphene layer is provided with a skin-friendly layer, the skin-friendly layer and the graphene layer are connected by an adhesive layer, the reflective layer, the first ultraviolet-resistant layer, the cotton cloth layer, the second ultraviolet-resistant layer, and the graphene layer are connected by fiber filaments, one ends, close to the reflective layer, of the fiber filaments are fixedly connected with a base cloth layer. The beneficial effects are as follows: the fabric can not only reflect ultraviolet rays and shield ultraviolet rays, but also can absorb ultraviolet rays and resist penetration of ultraviolet rays, children are effectively protected, and the impact of ultraviolet rays on the children is reduced.