The present invention discloses a medical cooling polymer hydrogel cold therapy patch and belongs to the technical field of medical polymer materials. The medical cooling polymer hydrogel cold therapypatch is mainly prepared from the following raw materials: polyphosphazene, selenium dioxide, silk fibroin, purple sweet potato powder, calcium chloride, xanthan gum, purified water, methylpyridine,polyethylene glycol, methyl iodide, sodium carboxymethyl cellulose, PVA, sodium tetraborate, sodium hydroxide, polypropylene glycol and a mixture of traditional Chinese medicines. The anti-aging hydrogel cold therapy patch is simple in preparation technology, suitable in gel strength and long in duration of cold compress curative effects, an ideal cold compress patch product, and suitable for large-scale production applications. A hydrogel layer combines traditional hydrogel cold compress and calcium chloride cold compress, and is good in auxiliary treatment effects, free of any side effects and easy to use.