251 results about "Dialyzates" patented technology

A dialyzer mount arranged to support a plurality of differently sized and / or shaped dialyzer units and to accommodate different distances between dialysate connections on the dialyzer units. The dialyzer mount, which may be located on a front panel of the dialysis unit, may include a pair of flange portions that are each arranged to engage with a respective dialysate quick-connect fitting connected to a dialysate port of the dialyzer. Each flange portion may be arranged to engage with a groove on the quick connect fitting that is located between a portion of the base of the quick connect fitting and a slide element of the quick connect fitting. One flange portion may include an adjustable support that is moveable, e.g., in a vertical direction.

A membrane module for hemodiafiltration having a cylinder-shaped housing and a bundle of hollow-fiber membranes capable of supporting fluid flow and arranged in the direction of the longitudinal extent of the housing. The ends of the hollow-fiber membranes are embedded in a fluid-tight manner in first and second sealing compounds joined to the housing inner wall in a fluid-tight manner. The exterior space formed around the hollow-fiber membranes and delimited by the first and second sealing compounds and the housing inner wall is divided along the longitudinal extent of the housing into a dialyzate space and a substituate space by a dividing wall that is made from a substantially dimensionally stable material. The dividing wall encloses each hollow-fiber membrane and is arranged substantially transversely to the hollow-fiber membranes. The dialyzate space and substituate space each have at least one opening for introducing or draining a fluid. In the exterior space, at least one throttle is arranged by which the dialyzate space and substituate space are in fluid communication with each other.

A hemodiafiltration system for treating blood which has module having a housing in which hollow-fiber membranes are arranged in the direction of the longitudinal extent and are embedded at their ends in first and second sealing compounds joined to the inner wall of the housing in a fluid-tight manner. The membrane module also has a dialyzate space and a substituate space separated from the dialyzate space in a fluid-tight manner by a continuous dividing wall. The membrane module further includes means for delivering and withdrawing a dialyzate to and from the dialyzate space, and means for delivering a substituate to the substituate space. The hollow-fiber membranes are used for blood treatment, filtration of the substituate, and delivery of the substituate to the blood. An exterior space is formed around the hollow-fiber membranes that is delimited by the inner wall of the housing and sealing compounds and is divided along the longitudinal extent of the housing by a dividing wall into the substituate space and the dialyzate space, the dividing wall encloses each individual hollow-fiber membrane.

The invention relates to a method for adjusting and controlling the contents of chlorine and nitrate in a tobacco extract. The invention aims at solving the problems of complicated technique, relatively high cost, easily damaged original aromatic components in tobacco and chemical agent residue in the extract in adjusting and controlling the contents of the chlorine and the nitrate in the tobacco extract during the production of reconstituted tobacco leaves in the existing paper-process. The technical keys are as follows: the method is characterized in that a tobacco raw material extract used in the production of the reconstituted tobacco leaves in the paper-process is selected and the concentration thereof is adjusted and controlled to meet operation requirements, and then the extract is put into a nano filtration membrane circulating device for circulation and filtration and a trapped liquid with the chlorine and the nitrate removed and trapped by a nano filtration membrane is obtained; the trapping liquid is used as a material which is coated on and refilled into a substrate during the production of the reconstituted tobacco leaves in the paper-process, and a dialyzate containing high-content of the chlorine and the nitrate the salt of which is removed through reverse osmosis treatment, can be used for extracting process water or washing water of the nano filtration membrane and separating equipment, and the like.

The invention discloses a technology for realizing zero discharge of waste water caused by white carbon black production. The technology is characterized by comprising the steps: 1, firstly, filtering the waste water caused by white carbon black production by a ceramic membrane to obtain ceramic membrane dialyzate and ceramic membrane concentrated liquid; 2, carrying out plate-frame pressure filtration on the ceramic membrane concentrated liquid to obtain filter residue which is silicon dioxide, recycling the silicon dioxide, enabling filter press water to enter a collecting tank and carrying out circulating treatment on the filter press water; 3, carrying out primary nanofiltration on the ceramic membrane dialyzate, collecting primary nanofiltration concentrated liquid to obtain sodium sulfate concentrated liquid, and carrying out evaporation and concentration to obtain sodium sulfate; and 4, carrying out primary reverse osmosis on primary nanofiltration dialyzate to obtain primary reverse osmosis dialyzate and primary reverse osmosis concentrated liquid, and carrying out evaporation and concentration on the primary reverse osmosis concentrated liquid to obtain sodium sulfate, wherein the primary reverse osmosis dialyzate is produced water and is recycled for white carbon black production. The technology has the beneficial effects that the operation cost is low; inorganic salts and water resources can be recycled, and zero discharge and a win-win situation of environmental protection benefit and economic benefit can be realized.

The invention discloses a method for preparing a CuS photothermal therapy nano material with good biocompatibility. A one-pot method is adopted and the preparation method comprises the following steps: weighing a biomacromolecule in a container, adding water, stirring and dissolving, adding a Cu(NO3)2 solution, fully stirring and mixing uniformly, adding a NaOH solution, and finally adding a Na2S solution (the mol ratio of Cu to S is 1:2), fully stirring and uniformly mixing, putting into a water bath pot at the temperature of 90 DEG C, and stirring for 30 min to obtain a dark green solution; dialyzing and purifying the obtained CuS nano material, wherein the dialyzing time is 24h, and water is changed every 4h; and freezing and drying the obtained dialyzate to obtain the product. The reagent used in the invention is green and environmentally friendly, the preparation method is simple by performing heating reaction at the temperature of 90 DEG C, the operation is safe and simple, toxin is small, the cost is low and the large-scale popularization can be easily realized. The prepared nano material is small in size, good in water solubility, stable in near-infrared thermal performance and good in biocompatibility without immunogenicity.

A treatment of ammonia chloride waste-water zero discharge in rare earth production is carried out by taking waste water containing ammonia chloride as object, chemically and physically purifying, membrane separation treating by secondary or tertiary or multi-stage inverse penetration device, evaporation concentrating for concentrate, steaming ammonia to obtain ammonia water, recovering calcium chloride product, and split flowing dialyzate to recover. It achieves low cost, energy saving, simple process and zero discharge.

The invention provides a method for testing plant endogenous hormones, comprises the following steps of: carrying out microdialysis sampling on a plant body; carrying out sample injection on the acquired dialyzate on a high-performance liquid chromatograph; and simultaneously separating and determining four main plant endogenous hormones: gibberellic acid (GA), cytokinin (6-BA), indolylacetic acid (IAA) and abscisic acid (ABA). Compared with the traditional method for testing the plant endogenous hormones, the invention realizes the intravital test on the plant endogenous hormones and can reduce the damage to the plant body to maximum extent; in addition, the invention can simply and conveniently extract samples, has simple operation, can really reflect the change of the content of the endogenous hormones in the plant body in the vital movement progress and realize the real-time, intravital and on-line test on the plant endogenous hormones.

A papermaking wastewater advanced treatment and recycling device and a method thereof relate to the treatment of papermaking wastewater. The invention provides a papermaking wastewater advanced treatment and recycling device which combines the nanometer catalytic electrolysis technology with the membrane technology, has lower cost and higher efficiency and can recycle wastewater, and a method thereof. The papermaking wastewater advanced treatment and recycling device is provided with a nanometer catalytic electrolysis system, a membrane filtration separation system and a membrane cleaning regeneration system. The method of the invention comprises the following steps: papermaking wastewater is extracted by a water pump and introduced in a nanometer catalytic electrolysis tank to perform nanometer catalytic electrolysis, then the obtained water is introduced in a filtering tank for filtration to remove the solid impurities, plankton, bacteria and colloid in wastewater and obtain the purified wastewater; and the purified wastewater is filtered and separated by the membrane filtration separation system to obtain dialyzate and concentrated solution, wherein the dialyzate is used for recycling; and one part of the concentrated solution flows back to the nanometer catalytic electrolysis system and the other part is directly discharged.

The invention discloses a method for treating vanadium pentoxide wastewater and circularly utilizing resources, and relates to industrial wastewater treatment and cyclic utilization of resources. The method comprises the following steps of: adjusting pH in the vanadium pentoxide wastewater, adding a reducing agent and reducing to trivalent chromium; adding a precipitator into the vanadium pentoxide wastewater, and separating to sludge and supernate after reaction; filtering the supernate, adsorbing the wastewater obtained by filtration to obtain purified wastewater, pumping the purified wastewater into a low pressure reverse osmosis system, and desalting to obtain dialyzate 1 and concentrated liquid 1; pumping the concentrated liquid 1 into a high pressure reverse osmosis system to carry out high pressure reverse osmosis desalting to obtain dialyzate 2 and concentrated liquid 2, combining the dialyzate 2 and the dialyzate 1 to obtain regenerating water as water for vanadium leaching in a leaching station in production, and causing the concentrated liquid to enter an electroosmosis system; feeding the concentrated liquid 2 into the electroosmosis system through a water pump and concentrating the concentrated liquid 2, causing the generated dialyzate 3 to enter the high pressure reverse osmosis system, and continuously and circularly treating, and discharging the concentrated liquid 3 into a salting ball forming station salt water pool in production of the vanadium pentoxide as salt water.

The present method of low-caffeine high-purity tea-polyphenol by using resin adsorption process includes the following steps: using green tea as raw material, adding pure water to make extraction, centrifugal filtering, clarifying to obtain green tea extract, ultrafiltering clear liquor to obtain dialyzate, making the dialyzate be passed through polar macroporous adsorption resin to make adsorption and decolourization, and remove colouring matter impurity to obtain light-yellow effluent, making the light-yellow effluent be passed through ultrahigh cross-linking adsorption resin to make chromatographic adsorption to remove caffeine and obtain tea-polyphenol effluent with low caffeine content, nano-filtering, concentrating, spary-drying so as to obtain the target product tea-polyphenol.

The invention discloses a domestic sewage zero emission treatment method, which comprises the following steps of: (1) treating domestic sewage by the conventional treatment method; (2) performing advanced treatment on effluent obtained in the step (1) by using a reverse osmosis system to obtain reverse osmosis dialyzate and concentrated solution; (3) performing catalytic oxidation and biochemical treatment on the reverse osmosis concentrated solution successively; and (4) adding a flocculating agent into sludge produced in the step (1) and the step (3), making a mud cake and transporting. The domestic sewage is subjected to the conventional treatment, the effluent is subjected to advanced treatment by the reverse osmosis system, the reverse osmosis dialyzate of which the water quality can reach the standard of drinking water is used for daily life, and the further treated reverse osmosis concentrated solution of which the water quality can reach the water quality standard of non-drinking water is used for greening. The sewage can be fully utilized in a mode of treating the domestic sewage by stages, so that zero emission in the real sense is realized. The invention also discloses a domestic sewage zero emission treatment system.

The invention relates to a method for adjusting and controlling the content of nicotine in a tobacco extract. The invention aims at solving the problems of complicated technique, relatively high cost, easily damaged original aromatic components in tobacco and chemical agent residue in the extract in adjusting and controlling the content of the nicotine in the tobacco extract during the production of reconstituted tobacco leaves in the existing paper-process. The technical keys are as follows: the method is characterized in that a tobacco raw material extract used in the production of the reconstituted tobacco leaves in the paper-process is selected, a solvent is used for diluting the extract to a set concentration, the diluent obtained is put into an ultrafiltration membrane circulating device for circulation and filtration to obtain a trapped liquid which is low in nicotine content and trapped by a ultrafiltration membrane and a dialyzate which is high in nicotine content and permeates the ultrafiltration membrane, wherein, the trapped liquid is used as a material which is coated on and refilled into a substrate during the production of the reconstituted tobacco leaves in the paper-process and the dialyzate is used as a material with special usage.

The invention discloses an enzyme-assisted extraction method of high-purity laver polysaccharide, which belongs to the field of biomedicine. The seaweed is dried and ultrafinely pulverized to obtain seaweed powder, and the pulverized seaweed powder is subjected to supercritical CO2 extraction (extraction pressure is 31 MPa, temperature 50 ° C, extraction for 3 hours, separation pressure 5.6 MPa, temperature 55 ° C) degreased, and then The defatted seaweed powder was mixed with 50 times of pure water, 0.5% papain was added to extract at 70°C for 3.5 hours, the filter residue was discarded by centrifugation at 5000 rpm for 15 minutes, the extract was concentrated to 1 / 4 of the original volume by rotary evaporation, and 80% of Trichloroacetic acid (TCA) was mixed to 2% of the total volume of the solution, and then the solution was reacted in a 70°C water bath for 20 minutes to remove protein, centrifuged at 5000 rpm for 30 minutes to remove the precipitate, and dialyzed in deionized water for 48 hours to remove trichloroacetic acid. The dialysate was collected, and then Slowly add 4 times the volume of 95% ethanol, alcohol precipitation at 4°C for 12h, centrifuge at 5000rpm for 10min, discard the supernatant, wash the precipitate with absolute ethanol, acetone, and ether for three times, respectively, and dry it in an oven at 55°C. Seaweed crude polysaccharide. The yield of papain extraction technology was 26.07%, and the purity reached 84.32%. Compared with hot water extraction, the time was shortened by 50% and the yield was increased by 46%. The obtained laver polysaccharide can be widely used as the base material of medicine and health food.

A method for extracting multiple active ingredients of blueberry fruits comprises the steps that dried and smashed blueberry peel residues are firstly subjected to enzyme hydrolysis, then microwave extraction and solid-liquid centrifugal separation are performed, refined filtration is performed by using micropore filter bags, and filtrates are combined; discoloring and impurity removal are conducted on the mixed filtrate by using an ultra-filtration membrane, membrane re-separation is performed, vacuum concentration, alcohol precipitation and drying are conducted on the trapped filtrate to obtain a blueberry polysaccharide extract; passing-column absorption is conducted on the ultra-filtrated dialyzate through macroporous resin, then ethyl alcohol is used for elution and desorption, a desorbed solution is separated and concentrated by using a nano-filtration membrane, and vacuum concentration and freeze drying are conducted on the trapped solution to obtain a blueberry anthocyanin and original anthocyanin combined extract; nano-filtration membrane dialysate is subjected to further separation and dehydration by using a reverse osmosis membrane, vacuum concentration and spray drying are conducted on the trapped solution to obtain a blueberry ellagic acid etract. By means of the method, multiple effective ingredients including polysaccharide, original anthocyanin, anthocyanin, ellagic acid and the like of blueberries can be obtained, the extracts are higher in purity, good in quality, and a production process is green and capable of saving energy and is environmentally friendly.

The invention discloses a medical infusion bag. The infusion bag is manufactured by using polypropylene and polyethylene and styrene-ethylene / butylene-styrene block copolymer. The infusion bag manufactured by adopting the technical scheme has the advantages that: the air-tightness and the steam resistance are excellent, the chemical stability is high, and the infusion bag is suitable to be used for manufacturing liquid medicinal products requiring high-temperature disinfection and sterilization; the transparence is high, and the detection of foreign materials when the infusion bag is produced and used is ensured; the softness is high, the falling resistance is high, the heat-sealing property is high, the high-temperature resistance is high, and the infusion bag can be sterilized at the temperature of 121 DEG C; because the infusion bag does not contain halogens, the infusion bag does not cause any environmental pollution when processed after use; and simultaneously, the barrier property is high, the chemical inertness and the biological inertness are high, the compatibility with medicaments is good, and the infusion bag can be used for packaging various kinds of common fluid, enteral nutrient fluid, parenteral nutrient fluid, dialyzate, flushing fluid, treating type large-capacity injection and the like.

The invention relates to a fluorine-doped fluorescent carbon quantum dot preparing method. The method comprises the steps of adding 7-250 mmol / L glucose dispersion liquid into a polytetrafluoroethylene hydrothermal reaction still, and then adding hydrofluoric acid solution, wherein the volume ratio of the hydrofluoric acid solution to the glucose dispersion liquid is 2.5-12.5%; placing the reaction still in a muffle furnace for reaction lasting 6-24 h at 160-210 DEG C; making the obtained solution pass through a filter membrane with bore diameter of 0.22 micron to remove large particles, and adding obtained filtrate into a dialysis bag for dialysis, wherein deionized water serves as dialyzate and dialysis time is 2-7 days; transferring the product in the dialysis bag into a flask, and removing solvent through reduced pressure distillation; placing the solid in a vacuum drying oven to be dried for 48 h, so that a fluorine-doped fluorescent carbon quantum dot product is obtained. According to the method, operation is easy, sources of raw materials are wide, cost is low, yield is high, and chemical stability is high. The method can be applied to fields including photocatalysis, bioimaging and biochemical analysis.

The invention discloses a low-energy consumption seawater desalinating technology and a low-energy consumption seawater desalinating device. The seawater is input into a seawater desalinating reverse osmosis membrane separation system under the drive of a high-pressure pump after being pretreated to separate and hold back all ions by a seawater desalinating membrane so as to obtain membrane permeate and concentrate, and the membrane permeate is secondly separated by a low-pressure reverse osmosis membrane separation system to be taken as drinking water; the concentrate generated by the seawater desalinating reverse osmosis membrane separation system enters the low-pressure reverse osmosis membrane separation system through a pipeline to obtain membrane permeate and concentrate in a separating way, and the membrane permeate is taken as life non-drinking water; the concentrate generated by the low-pressure reverse osmosis membrane separation system is introduced into a nanofiltration membrane separation system through a pipeline to remove most salts in seawater through a nanofiltration membrane, and the obtained membrane permeate can be used as water for flushing the toilet; one concentrate end is connected with an energy recovery device to recover the pressure energy of the concentrate to push a rotating shaft of the high-pressure pump, so that the pressure energy can be converted into the pressure energy for enabling the ultrafiltration membrane dialyzate to enter the seawater desalinating reverse osmosis membrane system, and the energy consumption for the high-pressure pump can be reduced, therefore, the special effects such as low energy consumption, high recovery rate, diversity of produced water quality and the like can be realized.

The invention relates to preparation methods of Chuanxiongchatiao granule extracts and preparations thereof. Specifically, the preparation method of the preparations comprises the following steps: (1) taking the rhizome of chuanxiong, radix angelicae, angelica polyclada, asarum, divaricate saposhnikovia root and liquorice, adding water to decoct the medicines, filtering the decoction and keeping the soup for later use; (2) extracting volatile oils from mint and schizonepeta for later use, filtering the water solution of the volatile oils and merging the filtrate with the soup obtained in the step (1); (3) carrying out nanofiltration on the merged soup obtained in the step (2) with a film, abandoning the dialyzate and spray drying the obtained concentrates to prepare extract powder as the extracts of the preparations; and (4) uniformly doping the volatile oils obtained in the step (2) in the extract powder obtained in the step (3) and then optionally doping pharmaceutically acceptable auxiliary materials uniformly to prepare the preparations. The invention also relates to the extracts and preparations obtained by the methods. The methods have the characteristics of low cost, low possibility of damage of thermosensitive ingredients and the like.

Heparan sulfate originating from rat tissue and its production are disclosed. The procedures is carried out by homogenizing rat tissue, degreasing, hydrolyzing by protease, hydrolyzing by alkali, deproteinizing, centrifugalizing, taking out purified liquor, dialyzing, depositing dialyzate by cetylpyridinium chloride, hydrolyzing by RNase and chondroitinase ABC, and separating by ionic exchanging column. It has special raw material, better product anticoagulant and antiradiation performances, and various Heparan sulfate. It can be used for research on medicinal molecular model structure and protein interaction. I

The invention belongs to the technical field of deep processing of agricultural products, and particularly discloses a method for preparing fructooligosaccharide by taking waste molasses as a raw material. The method is characterized in that the method comprises the steps of taking the waste molasses produced during the sucrose refining production course, preparing a waste molasses solution with a mass concentration of 15-20%, dialysing with a 500Da nanofiltration membrane, concentrating a dialysate, adding the dialysate to immobilized transfructosylase directly, adjusting a pH value to be 5-6, saccharifying at 38-42 DEG C for 10-20h, filtering, decolorizing, hybridizing, concentrating, drying, and obtaining the finished solid fructooligosaccharide. According to the method, the waste molasses raw material replaces sucrose for preparing the fructooligosaccharide; the method is abundant in raw material source, simple and easy to operate, low in production cost and reasonable in technological design; the product quality meets a national standard of the fructooligosaccharide; the method is suitable for industrial production; economic benefits can be remarkably increased; and an additional value of a byproduct can be increased.

The invention relates to a whole blood perfusion bioartificial liver system which comprises a blood circulation part and a bioartificial liver circulation part. The blood circulation part comprises a blood input port, a blood pump, a hollow fiber column and a blood feedback port which are sequentially connected. The bioartificial liver circulation part comprises a circulation pump, a constant temperature heater, an oxygenator and a bioreactor which are sequentially connected. An inlet of the circulation pump is connected with an outlet of an outer cavity of the hollow fiber column. A liquid outlet of the bioreactor is connected with an inlet of the outer cavity of the hollow fiber column. The bioartificial liver circulation part is further provided with two bypass pipelines. The whole blood perfusion bioartificial liver system further comprises a liquid input part and a dialyzate drainage part. The whole blood perfusion bioartificial liver system is safe, reliable and efficient, achieves continuous treatment, combines the venous transfusion and part kidney dialysis functions, is comprehensive, and provides effective support for hepatic failure patients.

A dialyzer in which a nearly cylindrical case is provided therein with a hollow fiber bundle made of a plurality of hollow fiber membranes, a blood flow path formed by lumens of the hollow fiber membranes, a dialyzate flow path formed by a space between the inner wall of the case and the hollow fiber membranes and a cylindrical heat-shrinkable tube provided on the outside of the hollow fiber bundle and at least a part of which can be shrunk by heating, and a method for manufacturing the dialyzer.

The invention provides a method for preparing a water-soluble nitrogen phosphorus codoped carbon quantum dot by taking glucose, strong phosphoric acid and ethanediamine as raw materials. The method comprises the following steps: S1, preparing a glucose precursor solution; S2, mixing the glucose precursor solution and strong phosphoric acid according to the volume ratio of (1-5):3 to obtain a first mixed solution; S3, heating the first mixed solution obtained in the S2 to obtain a brown solution; S4, putting the brown solution in the S3 under the ice-water bath condition, mixing the brown solution and ethanediamine according to the volume ratio of 5:(1-5) to obtain a second mixed solution, and filtering the second mixed solution to obtain filtrate; S5, dialyzing the filtrate to obtain dialyzate; and S6, evaporating the dialyzate to obtain the water-soluble nitrogen phosphorus codoped carbon quantum dot. The preparation method of the water-soluble nitrogen phosphorus codoped carbon quantum dot has the following advantages: the carbon source is rich and cheap; the preparation process is simple; the whole preparation process is pollution-free, non-toxic and environment-friendly; and large-scale preparation can be realized.

A carbon quantum dot preparing method is disclosed. The method includes cleaning a carbon-containing precursor in an ultrasonic cleaner, drying the carbon-containing precursor to obtain a dried product, adding the dried product to an autoclave, adding a NaOH solution, sealing the autoclave, putting the autoclave to a drying oven, performing a hydrothermal reaction, taking the autoclave out after the autoclave is cooled, filtering a liquid mixture in the autoclave with double layers of filter paper to obtain a filtrate, centrifuging and filtering the filtrate to obtain a supernatant liquid, adding the supernatant liquid into a dialysis bag, performing dialysis, putting the dialyzate in the dialysis bag to a freeze-drying oven, and freeze-drying the dialyzate to obtain solid carbon quantum dots. According to the method, waste paper, waste cloth or waste cotton which are wide in source, economical and environment friendly are adopted as the carbon-containing precursor, and the quantum dots prepared by a hydrothermal process and through steps of filtration, centrifugation, dialysis, and the like are high in yield, uniform in structure and good in dispersibility.

The invention discloses a peritoneal dialysis treatment device and an operation method thereof, wherein the peritoneal dialysis treatment device comprises an irrigation and drainage channel, a waste drain channel and a liquid supply channel, the irrigation and drainage channel is connected with the abdominal cavity of the human body, the waste drain channel is used for draining the liquid in the irrigation and drainage channel drained from the abdominal cavity, the liquid supply channel is connected with a liquid bag which is used for holding dialyzate, each of the irrigation and drainage channel, the waste drain channel and the liquid supply channel is correspondingly connected with one of three liquid flow holes which are non-uniformly formed in a three-way valve, and each two channels are connected under certain state. The irrigation and drainage channel is further provided with an irrigation and drainage pump which is a bidirectional pump, and the liquid supply channel is further provided with a heater which is used for heating the dialyzate and a heating pump which is used for pumping the dialyzate to the heater. The peritoneal dialysis treatment device and the operation method thereof overcome the disadvantages of complex transfusion system structure, high processing precision requirement and complex operation of the existing peritoneal dialysis machine and have advantages of simple structure, easiness in processing and convenience in operation.

The invention relates to an integrated blood purification device with a blood perfusion structure and a blood dialysis structure. The integrated blood purification device comprises the perfusion structure, the dialysis structure and a shell. The perfusion structure and the dialysis structure are fixedly arranged in an inner cavity of the shell to form an integrated connecting structure. A blood input port is formed in the top face of the shell, a blood output port is formed in the bottom face of the shell, the lower portion of the side face of the shell is provided with a dialyzate input port, and the middle or upper portion of the side face of the shell is provided with a dialyzate output port. The perfusion structure is located on the upper portion of the shell. The dialysis structure is located in the middle or lower portion of the shell. The blood input port is communicated with the blood input end of the perfusion structure, the blood output end of the perfusion structure is communicated with the blood input end of the dialysis structure, the blood output end of the dialysis structure is communicated with the blood output port of the shell, and therefore the integrated blood purification device with the coherent blood perfusion and blood dialysis functions is formed. When in use, the integrated blood purification device has the advantages that no pollution is produced in the overall process, connecting positions are stable, firm and safe, the dialysis device is repeatedly started without the need of exhausting air again, operation is easy, and safe and practical effects are achieved.

The present invention discloses a collagen prepared by utilizing fowls kin as raw material, and the prepared fowl skin collagen is formed from alpha and beta chains. Said preparation method included the following steps: cleaning fowl skin, soaking the cleaned fowl skin in alkaline solution, then using deionized water to wash the alkali-treated fowl skin, soaking the above-mentioned fowl skin in acidic buffer liquor, filtering, centrifugalizing, collecting supernatant and dialyzing untie the dialyzate is made into neutrality. Said invention contains no gamma chain, its alpha chain content is high and beta chain content is low.

Provided are a hemodialyzer and a hematodialysis device. The hemodialyzer comprises an outer shell, a fiber bundle formed by a hollow fiber pipe, an end cover, packaging glue, an annular flow guiding distribution ring, a dialyzate inlet, a dialyzate outlet, a blood inlet and a blood outlet. The annular flow guiding distribution ring is placed at the positions right opposite to the dialyzate inlet and / or the dialyzate outlet, one end of the annular flow guiding distribution ring is connected to the tail end of the outer shell, and the other end of the annular flow guiding distribution ring inclines in the longitudinal direction of the outer shell toward the dialyzate inlet or the dialyzate outlet right opposite to the annular flow guiding distribution ring. The hollow fiber pipe is made of a polyether sulfone hollow fiber film, and the spinning dope of the polyether sulfone hollow fiber film comprises, by weight, 250 parts-650 parts of modified polyether sulfone blends, 20 parts-400 parts of hydrophilia molecular compounds, 1 part-90 parts of nano-modification hydroxide radical titanium dioxide blends and 20 parts-120 parts of alcohols solvents. The hemodialyzer improves the contact area and the removal rate of dialyzate and the surface of the fiber pipe, and the high removal rate and the high ultrafiltration coefficient are achieved.