44 results about "Dialyzates" patented technology

The invention provides synthesis of a T-2 toxin antigen and preparation and application of a monoclonal antibody. Relates to the technical field of biotoxin detection. The preparation method of the T-2 toxin antigen comprises the following steps: step 1, synthesizing an immunogen T-2-BSA by adopting a carbodiimide method, dissolving 2mg of T-2 adipic acid with 0.5 mL of dimethylformamide, and recording as a solution A; 5 mg of bovine serum albumin and 3 mg of EDC are dissolved with a 2-morpholine ethanesulfonic acid buffer solution with the pH being 5.5, and the solution is marked as a solution B; step 2, under the condition of stirring, dropwise adding the solution A into the solution B, stirring for 18 hours in a dark place at 4 DEG C, then dialyzing for 3 days by using a phosphate buffer solution, changing the solution once a day, centrifuging the dialysate for 10 minutes at 3,500 r / min, and discarding the precipitate; the adipic acid is coupled with the T-2 toxin through a chemical method, and the unique step enriches the structural characteristics of the hapten, so that the prepared T-2 toxin complete antigen is excellent in immune effect, can efficiently excite immune response of an organism, and shows high specificity and sensitivity.

This invention discloses a production process for a carbon material used to adsorb toxic substances from dialysate, comprising the following steps: S1, crushing fruit shells; S2, mixing the selected fruit shells with a cellulase solution and performing full enzymatic hydrolysis in an enzymatic hydrolysis chamber; S3, mixing the hydrolyzed fruit shells with a phosphoric acid solution and impregnating them in an oven; S4, filtering the impregnated fruit shells and drying them in an oven; S5, placing the dried fruit shells in a tube furnace for carbonization and activation treatment; S6, washing the activated material with clean water and recovering the phosphoric acid; S7, after drying, an adsorbent carbon material with a well-developed meso- and macroporous pore structure and a high specific surface area is obtained. Compared with the prior art, this invention uses an enzymatic hydrolysis method, which allows the activator to fully penetrate into the interior of the fruit shell, causing some biomass components in the fruit shell to dissolve and form channels, facilitating the penetration of the activator solution and improving the adsorption effect of the carbon material.

A hydraulic system and method are provided for breaking-up, dislodging, removing, and preventing the build-up of biofilm in a dialysate pathway of an extracorporeal blood treatment device. The dialysate pathway can include a dialyzer discharge line, a drain line, a dialyzer feed line, and a bypass system. At least one ultrasonic device can be positioned and configured to generate ultrasonic waves in the dialysate pathway and to propagate the ultrasonic waves along at least a portion of the dialysate pathway. The ultrasonic waves can be used to break-up biofilm. An ionizing electrode pair can also, or instead, be implemented to break-up, dislodge, remove, and prevent a build-up of biofilm. The system and method can particularly be implemented and useful in non-disposable portions of a hydraulic system of an extracorporeal blood treatment device.

This invention relates to the field of carbon nanomaterial preparation technology, specifically a high-yield preparation method for carbon quantum dots and its application. The preparation method includes: adding citric acid, ethylenediamine, EDC, and NHS to deionized water, stirring at 60-90°C for a preset time to obtain a mixed solution; subjecting the mixed solution to a hydrothermal reaction, cooling to room temperature after the reaction is complete, and then centrifuging, filtering, and dialyzing; freeze-drying the dialysate to obtain carbon quantum dots. This invention combines EDC and NHS pretreatment with a hydrothermal method to prepare carbon quantum dots. The solvent used is water, which is non-toxic, harmless, safe, and reliable. The process is simple, safe, and environmentally friendly. Simple pretreatment can greatly improve the yield of carbon quantum dots while ensuring quantum efficiency. The preparation equipment is simple, the process is safe, and it consumes fewer resources, which is conducive to large-scale production.

The invention provides a lactobacillus fermentation extraction method of marine red algae polysaccharide and application of the marine red algae polysaccharide, and the method comprises the following steps: mixing marine red algae powder with water, and carrying out pasteurization at 60-70 DEG C for 20-40 minutes; adding lactobacillus plantarum into the sterilized marine red algae turbid liquid, and performing fermentation culture to obtain a marine red algae fermentation mixed liquid; heating and extracting the marine red algae fermentation mixed solution at 85-95 DEG C for 1.5-2.5 hours, centrifuging, collecting supernate, carrying out rotary evaporation and concentration to 1 / 5 of the original volume, then adding ethanol, standing overnight, discarding the supernate, adding distilled water into precipitate for redissolving, and deproteinizing by using a Sevag method to obtain a polysaccharide solution; and dialyzing the polysaccharide solution, and concentrating and freeze-drying the dialysate to obtain the marine red algae polysaccharide. According to the method, the low-molecular-weight modified polysaccharide is obtained through lactobacillus plantarum fermentation, extraction and purification, and the low-molecular-weight modified polysaccharide is high in sulfate group content, loose in structure, capable of remarkably inhibiting AGEs-induced intestinal cell oxidative stress and inflammatory reaction, capable of being used for preparing the glycosylation injury resisting medicine and good in industrialization prospect.

The utility model belongs to the technical field of blood purification. The dialyzer shell comprises a first barrel, a second barrel, a dialysate connector, reinforcing ribs and a first boss, the first barrel is arranged at the two ends of the second barrel, the dialysate connector and the first boss are arranged on the outer side of the first barrel, the dialysate connector is perpendicular to the axis of the first barrel, the first boss is arranged in the mode that the first barrel protrudes outwards, and the reinforcing ribs are arranged on the first boss. The first boss is located on the side, close to a port of the first barrel, of the dialysate connector, a plurality of reinforcing ribs are arranged between the dialysate connector and the first barrel, one reinforcing rib is connected with the first boss, and the other reinforcing ribs are connected with the outer wall of the first barrel in an arc mode. The first boss is arranged on the outer side of the first barrel, one reinforcing rib is connected with the first boss, the other reinforcing ribs are connected with the outer wall of the first barrel in an arc mode, sharp points can be eliminated, the wall thickness of the root of the dialysate connector is kept uniform, generation of internal stress is reduced, and therefore the strength of the dialysate connector is enhanced.

The dialysate barrel feeding device comprises a first conveyor and a second conveyor which are sequentially arranged in the dialysate barrel conveying direction, the discharging end of the first conveyor is in butt joint with the feeding end of the second conveyor, and the conveying speed of the first conveyor is smaller than that of the second conveyor; the barrel separating and clamping assembly is located in front of the joint of the first conveyor and the second conveyor and comprises a pair of oppositely-arranged clamping pieces, the clamping pieces are located on the two sides of the first conveyor correspondingly, and the distance between the clamping pieces is smaller than the width of a dialysate barrel; friction force between the first conveyor and the dialysate barrel and friction force between the second conveyor and the dialysate barrel can drive the dialysate barrel to leave the clamping piece; the distance between the contact position of the clamping piece and the dialysate barrel and the joint of the first conveyor and the second conveyor is smaller than the length of the dialysate barrel. The dialysate barrel separating and counting device can accurately and effectively separate and count dialysate barrels.

The utility model relates to the technical field of dialyzers, in particular to a glue injection cover of a dialyzer. The glue injection cover of the dialyzer comprises a dialysate tube, a glue injection cover body, a hollow fiber membrane and a groove block, the glue injection cover body is clamped on a dialyzer shell, the dialysate tube is connected and communicated with the dialyzer shell, the hollow fiber membrane located in the dialyzer shell is connected to the glue injection cover body, and the groove block is connected to the hollow fiber membrane. A plurality of grooves are evenly formed in the glue injection cover along the circumference, a plurality of groove blocks are further arranged on the glue injection cover, and the groove blocks and the grooves are distributed at intervals. The polyurethane adhesive flows in from the sintering end surface of the hollow fiber membrane and flows along the fiber direction of the hollow fiber membrane, so that the resistance of the polyurethane adhesive in the flowing process is reduced, and the problem of insufficient filling of the polyurethane adhesive is effectively solved.

The utility model relates to a directional feeding device for a dialyzer end cover, a dialysate flow opening of the end cover is of a circumferential protruding structure, the directional feeding device comprises a straight vibration feeding assembly, a static material channel assembly, an end cover transferring mechanism and an end cover directional mechanism, the static material channel assembly is arranged in the conveying direction of the straight vibration feeding assembly, and the end cover directional mechanism is arranged on the end cover transferring mechanism. The end cover transferring mechanism clamps and moves the end cover, and a stop block and a deflector rod in the end cover orientation mechanism are matched to limit the rotation angle of the dialysate flow opening, so that the dialysate flow opening is forcibly corrected to the preset direction. The end cover feeding device solves the problem that in the prior art, when end covers are fed, the directions of dialysate flow openings of the end covers are inconsistent. The device can greatly improve the production efficiency and reduce the time and cost of manual adjustment.

The utility model provides a stacking device for a dialysate thermal shrinkage packaging robot, which can further improve the safety in the dialysate stacking process and ensure that dialysate thermal shrinkage packaging is not scratched or adsorbed to deform, and comprises a transverse moving component, a pressing component and an L-shaped supporting plate, the top of the vertical end of the L-shaped supporting plate is connected with the transverse moving assembly, the downward pressing assembly is assembled on the transverse moving assembly or a fixed assembly of the mechanical arm, the L-shaped supporting plate comprises a vertical fixed frame, a connecting cylinder and deformable comb teeth, and the top of the vertical fixed frame is connected with the transverse moving assembly; the connecting cylinder is a rectangular pipe body, and the bottom of the vertical fixing frame is connected to the top of the connecting cylinder; a rotating shaft is arranged in the connecting cylinder, a rotating motor is arranged at any end of the connecting cylinder, and the rotating motor is connected with the rotating shaft; a plurality of assembly holes are formed in one side of the connecting cylinder; the end of one deformable comb tooth is connected to the position of one assembly hole, and the smooth wedge-shaped tip end of the deformable comb tooth tilts upwards under the action of the rotating motor.

The application provides a preparation method of selenium-doped Prussian blue nanoparticles modified by a targeting polypeptide, and comprises the following steps: (1) synthesizing Prussian blue nanoparticles by a microwave method; (2) synthesizing selenium-containing Prussian blue by a gas-phase atomic deposition method; and (3) preparing selenium-doped Prussian blue nanoparticles modified by a targeting polypeptide: dissolving a tumor-targeting RGD cyclic peptide in ultrapure water, adding a catalyst N-hydroxysuccinimide and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and then stirring, then performing dialysis, adding the selenium-containing Prussian blue into the dialysate, stirring, centrifuging, resuspending and obtaining the selenium-doped Prussian blue nanoparticles modified by the targeting polypeptide. According to the preparation method, the selenium is naturally deposited on the surface of the Prussian blue by the gas-phase atomic deposition method, monodisperse selenium with controllable doping amount is formed, and the selenium-doped Prussian blue modified by the targeting polypeptide is prepared.

The application discloses a method for separating different size negatively charged metal oxide nanolayers, which comprises the following steps: preparing a negatively charged inorganic metal oxide material; dialyzing the inorganic metal oxide material with deionized water for 24 hours, and replacing the dialysate every 6 hours to obtain a colloidal suspension; dividing the colloidal suspension into n test groups, adding dilute hydrochloric acid to each group, shaking uniformly, and then standing to form an upper dispersion liquid and a lower precipitate; testing the Zeta potential of the upper dispersion liquid and the lower precipitate respectively, and determining the test group with the maximum Zeta potential difference; collecting the upper dispersion liquid and the lower precipitate of the test group with the maximum Zeta potential difference, centrifuging and washing, and then freeze-drying to obtain metal oxide nanolayers with different sizes. The material obtained by the solution method has a thinner thickness and a larger surface area, can expose rich active sites, and has a wide application prospect in the fields of energy and catalysis.

The utility model relates to the technical field of dialysate preparation, and provides a dialysate preparation device which comprises a cabinet, a display screen and a control switch are arranged on the top of the front wall of the cabinet, an installation groove is formed in the front wall of the cabinet, and a partition plate is fixed in the installation groove; the touch screen is arranged at the top of the cabinet through a lifting mechanism; the dialysate preparation instrument is arranged below the partition plate, and a liquid inlet of the dialysate preparation instrument is fixedly communicated with a liquid inlet pipe; by means of the technical scheme, the problems that in the prior art, when a dialysate preparation device supplements dialysate to different dialysate tank bodies, a connecting pipe needs to be taken down and installed on other dialysate tank bodies, operation is tedious, meanwhile, a touch screen of an existing dialysate preparation device is generally directly exposed in the external environment, and operation is inconvenient are solved. When the device is not used, dust accumulation and accidental touch easily cause failure of the touch screen, and the service life of the device is affected.

The present invention relates to a system for jointly producing erythritol and liquid sorbitol by using a corn starch, including a liquefaction tank, a saccharification tank, a filter and a nanofiltration assembly. The liquefaction tank is used to perform liquefaction for the corn starch, the saccharification tank is used to perform saccharification for the liquefied material, the filter is used to filter out impurities in the saccharified material to obtain a glucose liquid, and the nanofiltration assembly is used to perform nanofiltration for the filtered glucose liquid to respectively obtain a dialysate and a concentrate. The system further includes a fermentation and crystallization assembly for performing fermentation and crystallization for the dialysate to prepare crystalline erythritol, and a hydrogenation and evaporation assembly for performing hydrogenation and evaporation for the concentrate to prepare liquid sorbitol. The present invention further provides a method of jointly producing erythritol and liquid sorbitol by using a corn starch. The present invention not only improves the purity of erythritol but also obtains liquid sorbitol, thus improving the utilization value of the corn starch.

The present invention discloses a preparation method and application of Gd / Ho bimetallic doped carbon dots, relating to the field of nanomaterial technology. The method comprises the following steps: 1. Ultrasonication of urea, gallic acid, a Ho-containing compound, and a Gd-containing compound in deionized water to obtain a mixed emulsion; 2. Adding the mixed emulsion obtained in step 1 to a microwave oven for sealed, high-temperature reaction to obtain a reaction solution; and 3. Treating the reaction solution obtained in step 2 with deionized water, centrifuging it, and dialyzing the supernatant in water to obtain a dialysate. The dialysate is freeze-dried to obtain Ho / Gd-doped carbon dots. The carbon dots synthesized by doping Gd and Ho in the present invention simultaneously possess triple-modal imaging capabilities: fluorescence, magnetic resonance imaging, and computed tomography. All three imaging modalities exhibit excellent imaging capabilities, making them advantageous for practical applications in biological imaging.

The invention relates to the field of iron ion detection, and particularly provides a fluorescent probe for detecting iron ions as well as a preparation method and application of the fluorescent probe. The fluorescent probe is a fluorescent nano material and is prepared by taking alkanet as a carbon source. The method comprises the following steps: S1, pretreating alkanet to obtain dry powder; s2, carrying out pyrolysis on the dried powder; s3, performing ultrasonic extraction and centrifugation; s4, carrying out filtration and dialysis; and S5, freeze-drying the obtained dialysate to obtain the fluorescent probe. The powdery fluorescent probe is dissolved in water and mixed with a solution to be detected, the fluorescence emission spectrum of the mixed solution is detected, and iron ions in the solution are detected through the change of fluorescence intensity. Fluorescent carbon dots are prepared based on pyrolysis of alkanet, a conjugated structure is reserved, chemical modification is not needed, the fluorescent carbon dots are green, low in toxicity and uniform in particle size, carboxyl / hydroxyl and other functional groups are contained on the surface, the fluorescent carbon dots can be coordinated with Fe < 3 + >, and high-sensitivity selective detection is achieved.

The invention discloses selenium-enriched spirulina carbon dots as well as a preparation method and application thereof, and belongs to the technical field of medicines. The selenium-rich spirulina powder is obtained by taking selenium-rich spirulina growing to a logarithmic phase as a raw material, centrifuging, collecting and freeze-drying. Uniformly mixing the spirulina platensis with a catalyst and deionized water according to a mass ratio of 1: (0.1-0.8): 20, then putting the mixture into a high-temperature reaction kettle to react at 140-260 DEG C for 1.5-5.5 hours, dialyzing the reaction liquid for 24 hours after the reaction is finished, centrifuging, and freeze-drying the dialysate to obtain the selenium-enriched spirulina platensis carbon dots with the yield of 70-95%. The selenium-enriched spirulina carbon dots provided by the invention not only have the inhibition capability of alpha-amylase, alpha-glucosidase, cholesterol esterase and pancreatic lipase and the cholate binding capability, but also can improve the endogenous antioxidant defense capability of model organisms while removing exogenous oxidizing substances, so that the glycolipid metabolism balance is efficiently regulated and controlled.

The invention discloses a recombinant mussel mucoprotein hyperbaric oxygen modification method which comprises the following steps: S1, optimizing a mussel mucoprotein gene sequence, cloning the optimized mussel mucoprotein gene sequence into an expression vector, and constructing a recombinant plasmid; s2, transforming the recombinant plasmids into competent cells, and culturing to obtain engineering bacteria; s3, culturing and fermenting the engineering bacteria, centrifugally collecting thalli, adding a bacteria breaking solution to break the thalli, purifying and collecting eluent, and dialyzing to obtain dialysate containing non-viscous recombinant mussel mucin; and S4, continuously introducing pure oxygen into the dialysate containing the non-viscous recombinant mussel mucoprotein, and adding a reinforcing agent for reaction to obtain the viscous recombinant mussel mucoprotein. The invention relates to a mussel mucoprotein modification method based on combination of a solid-phase catalyst physical separation technology and high-pressure oxygen, which realizes a green process without exogenous enzymes / chemical additives. The purity of the obtained product is greater than or equal to 98.9%, the protein recovery rate is greater than or equal to 95%, the adhesion strength and the DOPA content are relatively high, and a high-purity and low-cost mass production solution is provided for the fields of medical adhesives and the like.

This invention proposes a method for synthesizing T-2 toxin antigen and preparing and applying monoclonal antibodies, relating to the field of biotoxin detection technology. The method for preparing T-2 toxin antigen includes the following steps: First, the immunogen T-2-BSA is synthesized using the carbodiimide method. 2 mg of T-2 adipic acid is dissolved in 0.5 mL of dimethylformamide, denoted as solution A; 5 mg of bovine serum albumin and 3 mg of EDC are dissolved in a 2-morpholine ethanesulfonic acid buffer solution at pH 5.5, denoted as solution B. Second, solution A is added dropwise to solution B under stirring. The mixture is stirred at 4°C in the dark for 18 hours, then dialyzed with phosphate buffer solution for 3 days, changing the solution daily. The dialysate is centrifuged at 3500 r / min for 10 min, and the precipitate is discarded. The unique step of chemically conjugating adipic acid to T-2 toxin not only enriches the structural characteristics of the hapten, but also results in a complete T-2 toxin antigen that exhibits excellent immunogenicity, efficiently stimulating the body's immune response and demonstrating high specificity and sensitivity.

The invention discloses a preparation method and application of a gleditsia sinensis saponin-silver ion antibacterial chelate, and belongs to the technical field of deep processing of natural products. The method comprises the following steps: (1) extracting gleditsia sinensis saponin by using a deep eutectic solvent, dialyzing an extracting solution, purifying by using macroporous resin, and drying to obtain high-purity gleditsia sinensis saponin; and (2) fully dissolving the prepared gleditsia sinensis saponin as a raw material in distilled water, adding silver nitrate to perform an ultrasonic chelation reaction, dialyzing after chelation is completed, centrifuging dialysate, taking supernatant, and freeze-drying to obtain the gleditsia sinensis saponin-silver ion antibacterial chelate which can effectively inhibit escherichia coli and staphylococcus aureus. The method is easy to operate, the efficiency of chelating the gleditsia sinensis saponin with the silver ions is high, the chelate is good in stability, and the gleditsia sinensis saponin has huge potential in the application aspect of serving as a green, environment-friendly, safe and efficient antibacterial functional surfactant.

The dialyzer assembly line comprises a rack (1), a conveying belt (2) is arranged on the rack (1), limiting clamping jaws (3) which are evenly distributed are arranged on the conveying belt (2), and a weighing mechanism (4), a blood cover assembly mechanism (5), an air tightness detection mechanism (6), a labeling mechanism (7) and a small cover installation mechanism (8) are sequentially arranged on the rack (1) in the conveying direction of the conveying belt (2). The weighing mechanism (4) is used for detecting the quality of the dialyzer and screening the dialyzer; the blood cover assembling mechanism (5) is used for installing blood covers at the two ends of the dialyzer passing through the blood cover assembling mechanism (5). The air tightness detection mechanism (6) performs internal air tightness detection through a blood cover opening and a dialysate opening of the dialyzer; according to the automatic dialyzer assembling machine, dialyzer weighing, blood cover assembling, air tightness detecting, labeling and small cover installing can be automatically carried out, and the dialyzer assembling and machining efficiency is improved. In addition, the assembling device has the advantage of being high in assembling precision.

The application belongs to the technical field of magnetic resonance imaging, and provides a magnetic resonance contrast agent based on active protein targeting, which comprises 3-6 parts of fibroblast activation protein targeting molecules, 6-8 parts of ferritin, 6-15 parts of KGDS tetrapeptide, 28-42 parts of dialysate, and 15-30 parts of paramagnetic metal salt, so that the application can realize long circulation in vivo, enhance targeting, reduce non-specific accumulation, reduce damage to normal tissues, and enhance the contrast effect.

The present invention aims to provide a method for measuring endotoxin concentration of dialysate with higher accuracy using a calibration curve made of water, and a kit for the method. The present invention provides a method for measuring endotoxin as follows: mixing a prescribed amount of a test sample with a dry powder containing a solubilizer reagent to prepare a first reaction solution, then incubating the first reaction solution for a prescribed time, mixing the first reaction solution with a dry powder containing a luciferase bioluminescence reagent under light shielding to prepare a second reaction solution, measuring the amount of luminescence of the second reaction solution, and measuring the endotoxin concentration of the test sample, which is dialysate or water, from the amount of luminescence, the second reaction solution having a sodium ion concentration of 250 to 390 mM, a calcium ion concentration of 0.5 to 10 mM, a chloride ion concentration of 250 to 361.5 mM, and a Tris concentration of 20 to 30 mM.

The utility model discloses a centering adjusting tool of a dialyzer, relates to the technical field of adjusting tools, and aims to solve the problem of low efficiency of manual butt joint of the dialyzer, the centering adjusting tool of the dialyzer comprises a back plate, and a plurality of groups of clamp units used for clamping the dialyzer are arranged on the back plate. Any group of clamp units comprises a first clamp assembly, a clamping assembly and a second clamp assembly which are sequentially arranged from top to bottom along the front surface of the back plate, the clamping assembly is used for clamping a dialyzer, and the first clamp assembly and the second clamp assembly are used for clamping and sealing a blood inlet and a blood outlet of the dialyzer respectively; the second clamp assembly moves in the direction close to or away from the clamping assembly, the first clamp assembly comprises a first connector in butt joint with a dialysate outlet of the dialyzer, the second clamp assembly comprises a second connector in butt joint with a dialysate inlet of the dialyzer, and the first connector and the second connector move in the direction close to or away from the dialyzer.

Apparatus (1) and method for producing a dialysate, the apparatus (1) comprising a forward osmosis (FO) unit (2) including a feed side (2a) and a draw side (2b) separated by a FO membrane (2c), the feed side (2a) being included in a feed liquid path (3) and the draw side (2b) being included in a draw liquid path (4), the FO unit (2) being configured to receive a dialysis concentrate solution at the draw side (2b) and a spent dialysate solution at the feed side (2a), such that an osmotic pressure difference between the draw side (2b) and the feed side (2a) transports water from the spent dialysate solution through the FO membrane (2c) to the dialysis concentrate solution, thereby diluting the dialysis concentrate solution to a dilute dialysis concentrate solution and dehydrating the spent dialysate solution to a dehydrated spent dialysate solution, and providing (S3) a hydrostatic pressure difference between the draw side (2b) and the feed side (2a) using one or more pressure pumps (7, 32). The apparatus (1) is configured to sense one or more characteristics of the diluted dialysis concentrate solution and / or the dehydrated spent dialysate, sense one or more pressures indicative of a hydrostatic pressure difference between the draw side (2b) and the feed side (2a), and control at least one of a flow rate of the spent dialysate to the feed side (2a), a flow rate of the dialysis concentrate solution to the draw side (2b), and the hydrostatic pressure difference based on the one or more characteristics of the diluted dialysis concentrate solution and / or the dehydrated spent dialysate and the sensed one or more pressures indicative of the hydrostatic pressure difference to produce a diluted dialysis concentrate solution.

The utility model discloses equipment for mounting a dustproof cover of a dialysate filter. The equipment comprises a conveying device, a membrane outer interface buckling cover device and a membrane inner interface buckling cover device, wherein the conveying device is mounted on a main frame; the membrane outer interface buckling cover device and the membrane inner interface buckling cover device are arranged on the side surface of the conveying device; the conveying device is used for conveying a filter, and the two membrane external connector cover buckling devices are symmetrically arranged on the two sides of the conveying device correspondingly; the membrane external interface cover buckling device comprises a first positioning mechanism for positioning a filter shell, a clamping mechanism for positioning a membrane external interface and a first cover buckling mechanism for buckling a dustproof cover; the two groups of in-membrane interface cover buckling devices are symmetrically arranged on the two sides of the conveying device respectively; each in-membrane interface cover buckling device comprises a second positioning mechanism used for positioning a filter shell and a second cover buckling mechanism used for buckling a dustproof cover; according to the utility model, automatic installation of the dustproof cover can be realized, and the safety of products and the high efficiency of production are ensured.