The invention relates to cattle and sheep universal feed additive and a preparation method thereof, belonging to the technical field of feeds and aiming at solving various problems of cattle and sheep caused by microelement deficiency in feeds. The additive comprises the raw materials of nickel salts, molybdate, CuSO4, MnSO4, FeSO4, ZnSO4, MgSO4, KI, CoCI2, Na2SeO4, amino acid, vitamin, flavoring agent, NaSO4, CaPHO4 and CaCO3. The additive is prepared from the raw materials by adopting the steps of crushing, mixing, and the like. In the additive, nickel element and molybdenum element are added on the basis of reasonably adapting multiple microelements, therefore, the matching of the microelements is more all-sided. The additive can enhance the immunity of cattle and sleep, coordinate and absorb nutrient substances and discharge toxic substances, eliminate parorexia of cattle and sheep, enhance the digestion and absorption functions and solve the problems of low production performance, easy morbidity, difficult hybridization and low baby animal survival ratio of cattle and sheep.