42 results about "Free agent" patented technology

Formulations or delivery systems are provided for controlled release of therapeutically active agents. The delivery systems are composed of polymer and lipid materials and may be prepared as a gel, paste, solution, film, implant or barrier depending on the intended application. The polymer component of the matrix is the naturally occurring biomaterial, chitosan, or a mixture of chitin and chitosan. The lipid component may include phosphatidylcholine, phosphatidylserine, phosphatidylinositol, phosphatidyl or a mixture thereof. The delivery system may be used for delivery of hydrophilic agents, hydrophobic agents or combinations thereof. The therapeutically active agents may be formulated within the matrix as free agents or incorporated into particles. In a preferred embodiment the agents are incorporated into polymeric particles that are dispersed throughout the matrix.

The invention discloses a wash-free agent. The wash-free agent comprises the following components in parts by weight: 1-4 parts of a fluorocarbon copolymer, 5-11 parts of fatty glyceride, 2-5 parts of dialkyl dimethyl ammonium salt, 7-10 parts of alkyl trimethyl ammonium salt, 10-15 parts of quaternary ammonium salt, 1-3 parts of nanocrystalline cellulose colloid and 80-88 parts of water, wherein nanocrystalline cellulose in the nanocrystalline cellulose colloid is in a rodlike structure. The wash-free agent has the beneficial effects that the nanocrystalline cellulose is rodlike, carries negative charges on the surface, carries plenty of hydroxy and has affinity with water, so the nanocrystalline cellulose colloid shows a homogeneous and stable state in the water phase; the nanocrystalline cellulose has the adsorption function, so the fluorocarbon copolymer is distributed on the surface of the nanocrystalline cellulose and the surface of the nanocrystalline cellulose has lower tension; alkyl trimethyl ammonium salt is like a long chain and carries positive charges which neutralize with the negative charges on the surface of the nanocrystalline cellulose, so the nanocrystalline cellulose bonded with the fluorocarbon copolymer is intertwined and bonded with alkyl trimethyl ammonium salt to form long chain protective substances.

The invention provides an oil-bases stuck freeing agent composition for drilling fluid and a preparation method for the oil-based stuck freeing agent composition. The composition contains span-80 or span-60, span-20 or span-40, alkyl benzene sulfonic acid, petroleum acid, poly acid and mineral oil. The preparation method includes pumping raw material components into a reaction kettle, stirring, heating to 65 DEG C-95 DEG C, heat-preserving, stirring for reacting for 120-180 minutes, cooling to the room temperature and discharging for packaging. A using method of the stuck freeing agent includes determining density of stuck freeing spotting fluid according to safe density of the drilling fluid needed on the spot, stirring water, diesel, kerosene, or other mineral oil and the stuck freeing agent, adding barite and stirring to form stuck freeing spotting fluid emulsion, pumping the formed emulsion into a sticking section for soaking to unfreeze, and continuously pumping into the stuck freeing spotting fluid at a speed of 0.16-0.36M3 / h at the soaking stage until the sticking is released. The oil-based stuck freeing agent composition for the drilling fluid is convenient to use on the spot, small in using amount, convenient to conventionally carry for drilling crew, the maximum using amount is 8.7% of the stuck freeing spotting fluid, fluctuation range of stuck freeing time is narrow, the stuck freeing time of the stuck freeing spotting fluid with a density of 2.28g.cm<-3> ranges from 80 minutes to 160 minutes.