The invention discloses a capillary surface plasmon resonance sensor, which comprises an LED (light emitting diode) light source, a collimating lens, a telescopic system, a polarizing film, a capillary to double as a flow cell, and a CCD (charge coupled device) detector; an anti-reflection film is plated at the outer surface of the capillary, and a metal thin film is plated at the inner surface; and the polarized light obtained by the polarizing film is refracted into the capillary by the anti-reflection film arranged at the outer surface of the capillary, and then reflected into the CCD detector by the metal thin film arranged at the inner surface of the capillary. According to the capillary surface plasmon resonance sensor provided by the invention, the conversion of beam pattern and the excitation of SPR (surface plasma resonance) are achieved by the capillary plated with the metal thin film at the inner surface thereof, the traditional prism coupling mode is replaced, the capillary is synchronously to double as the flow cell, and namely the sensor is integrated with the flow cell; and in this way, the structure of the sensor system is smaller, the cost is lower, and the use is more convenient and more reliable.