The invention provides austenitic stainless steel for low temperature, a casting of austenitic stainless steel and a manufacturing method of the casting. The austenitic stainless steel comprises lower than 0.08% of C, 1.0%-1.6% of Mn, 0.6%-1.2% of Si, 17.0%-20.0% of Cr, 10.0%-13.0% of Ni, 2.0%-3.0% of Mo, 0.04%-0.12% of N and the balance Fe and impurities; in the impurities, P is smaller than or equal to 0.04%, S is smaller than or equal to 0.02%, Sn is smaller than or equal to 0.015%, As is smaller than or equal to 0.01%, Pb is smaller than or equal to 0.01%, Sb is smaller than or equal to 0.01%, and the sum of the Sn, the As, the Pb and the Sb is smaller than or equal to 0.035%. Chemical components are adjusted, the temperature points of Ms and Md (30/50) are controlled, the casting process is reasonably controlled, high-nickel welding rod selection, heat treatment temperature control and the like are achieved, the stability of a cast structure is guaranteed, and the good mechanical performance and size stability are achieved.