A modification method for a titanium-silicon molecular sieve comprises the following steps of mixing the titanium-silicon molecular sieve, a titanium source, a protective agent, an alkali source, a noble metal source, a reducing agent and water according to the proportion of 100:(0.001-1):(0.0001-5):(0.005-5):(0.005-10):(0.005-20):(500-10,000), and carrying out hydro-thermal treatment, wherein the protective agent is selected from one or more of polybenzimidazole, polypropylene, polyethyleneglycol, polystyrene, polyvinyl chloride, polyethylene and derivatives thereof, an anionic surfactant, a cationic surfactant, a non-ionic surfactant, glucose and cyclodextrin; and the reducing agent is selected from one or more of hydrazine, borohydride and sodium citrate. The titanium-silicon molecular sieve prepared by the method has high content of framework titanium and has high oxidation activity and selectivity as well as good stability.