The invention relates to the technical field of open unmanned supermarkets, and discloses a construction method of a self-service unmanned intelligent selling shop, which comprises a selling central control system, system connection and shop installation, the selling central control system adopts a mode of an Android system and a lower computer, and an electronic system is divided into three standard modules: an upper computer, the lower computer and a PLC servo motor. The Android mainboard adopts an ARM framework SOC chip design, onboard 4G full-network communication is achieved, the goods channel control mainboard adopts an STM32 single-chip microcomputer design, and a conveying system is executed by a servo motor controlled by a PLC. According to the construction method of the self-service unmanned intelligent selling shop, an electronic system is divided into three standard modules including the upper computer, the lower computer and the PLC servo motor, the design integration degree is high, adaptation is flexible, the comprehensive research and development manufacturing cost is low, the construction method is suitable for various selling scenes, functional standardized accessories are applied, adaptation is flexible, transportation is convenient, maintenance is easy, and the shop opening time is greatly shortened.