The invention provides healthy white spirit with kudzu vine flavor and anti-hypertension effect and a brewing method thereof. The healthy white spirit comprises the following raw materials in parts by weight: 1 part of fresh kudzu vine particles, 2 parts of purified water and 0.01 part of yeast; the fresh kudzu vine particles are made from timely harvested fresh kudzu vine root blocks selected from a well-bred kudzu vine root planting base; the yeast is a special tailor-made yeast which comprises more than 20 Chinese herbal medicines of ephedra, liquorice, white asarum and the like; and the purified water is alkalescent spring water or deep well water with pH value of 7.0-7.2. The method for brewing the method, provided by the invention, comprises the making steps of timely excavating, shaving, washing, crushing, granulating, steaming, mashing, fermenting and distilling. The product prepared by the method has the advantages of clear and transparent wine quality, good sensory effect, soft and sweet taste, no sharp taste, pure kudzu vine flavor, low degree and no floccus and has the effects of treating headaches, lowering blood pressure, reducing blood fat, expanding blood vessels, regulating blood sugar level, eliminating senile plaques and the like.