The invention provides an
isocyanate derivative as well as a preparation method and application thereof and a lubricating
grease composition. The structure of the
isocyanate derivative disclosed by the invention is shown as a formula (I), wherein an R group is selected from C1-C30 alkylene groups; the R'group is selected from
alkyl of C1 to C30; the A group is selected from a group shown in a formula (II) and a group shown in a formula (III); in the formula (II), R ''groups are selected from
alkyl groups, cycloalkyl groups or
aryl groups of C1 to C30, R'' groups are selected from
alkyl groups, cycloalkyl groups or
aryl groups of C1 to C30, and R ''groups are selected from alkyl groups, cycloalkyl groups or
aryl groups of C1 to C30; in the formula (III), the R ''group is selected from C1-C30 alkyl, cycloalkyl or aryl. The
isocyanate derivative has excellent extreme pressure anti-wear performance and can be used as a
thickening agent of a lubricating
grease composition or an additive of lubricating
grease, the lubricating grease composition prepared by taking the isocyanate derivative as the
thickening agent has excellent extreme pressure anti-wear performance, and the service life of lubricating grease can be prolonged.