The invention discloses a full-automatic cotton packaging machine system, which comprises a microcomputer control system, a movement system, a tightening system, a cutting system and a welding system, wherein the microcomputer control system outputs a signal to the movement system, the output end of the movement system is connected with the input end of the tightening system, the input end of the cutting system is connected with the output end of the tightening system, and the input end of the welding system is connected with the output end of the cutting system. The system has the advantages that the effect on welding by human factors, weather factors and the like is avoided, the labor cost is greatly reduced, the integral packaging speed is increased, the welding effect is improved, the stable and reliable welding is provided, the high-speed packaging line is favorable for accelerated popularization, the integral level of China cotton packaging is improved, and the automatic equipment packaging mode is adopted to reduce the unreasonable package bursting rate.