The invention discloses a high-performance water-cooled microwave ablation antenna, comprising a radiation head, a medium pipe, a semi-rigid coaxial electric cable, a needle rod, and a metal outer guide bush sleeved on the tail part of the medium pipe, wherein the semi-rigid coaxial electric cable penetrates through the axis hole of the metal outer guide bush and then is connected with the radiation head, the front end of the metal outer guide bush is sleeved on the medium pipe, the front end of the needle rod is sleeved on the excircle of the tail part of the outer guide bush, and the outer guide bush is in ohmic contact with the outer conductor of the semi-rigid coaxial electric cable and the needle rod. According to the high-performance water-cooled microwave ablation antenna disclosed by the invention, the needle rod and the medium pipe are connected together through the metal outer guide bush, the outer guide bush is in ohmic contact with the outer conductor of the semi-rigid coaxial electric cable and the needle rod, so that the structure precision of the microwave ablation antenna is improved, the boundary condition of the spatial electromagnetic field source of the antenna is not instable and unknown any more, and therefore, the performance and the main property parameters of the ablation antenna tend to be consistent and have certainty, so that the stability, efficiency and reliability of the ablation antenna are further improved.