The invention discloses a pharmaceutical composition for treating
climacteric syndrome and a preparation method thereof. The pharmaceutical composition is prepared from acanthopanax obouatus hoo, prepared
rehmannia roots, cinnamon, prepared aconite, medlar, prepared
ligustrum lucidum, yam, tuckahoe, prepared dodder, prepared
cistanche salsa, tree peony barks and
alisma orientale. The invention aims to solve the defects of the prior oral
solid pharmaceutical composition for treating
climacteric syndrome and provides a condensed
pill which is smaller and is easy to swallow as well as is easily accepted by patients. The preparation method of the pharmaceutical composition for treating
climacteric syndrome comprises the following steps: respectively crushing the yam, the cinnamon and the treepeony barks into
fine powder, and mixing the
fine powder for later use; adding ten times of water into other nine Chinese medicines comprising the prepared
rehmannia roots and the like to carry out decoction twice, wherein the first decoction time is 2 hours, and the second decoction time is 1 hour; combining decoction liquors, and filtering; under the conditions of the temperature of 65-70 DEG Cand the pressure of -0.08MPa, depressurizing and condensing the filter liquor into clear paste with
relative density of 1.08-1.12 at the temperature of 60-70 DEG C, cooling, adding the same amount ofalcohol, stirring, and standing for one night; filtering supernatant fluid, depressurizing and recovering
alcohol, and condensing the supernatant fluid into clear paste with
relative density of 1.20-1.25 at the temperature of 60-70 DEG C; mixing the clear paste and the fine power, depressurizing and
drying, crashing the dry paste, screening by a
sieve of 100 meshes, adding 10g of carboxyrnethyl
starch sodium and a proper amount of
starch, and mixing.