The invention discloses a high-pressure and constant-pressure two-section rubber membrane sealing air cabinet which is safer and more reliable. The air cabinet comprises a cabinet body, a T-shaped fence, a piston device and sealing rubber membranes, the T-shaped fence can rise and fall along the inner side of the cabinet body, the piston device can rise and fall along the inner side of the T-shaped fence, the sealing rubber membranes seal joints of the piston device and the T-shaped fence and joints of the T-shaped fence and the cabinet body respectively, the T-shaped fence comprises a T-shaped fence upper baffle plate and a T-shaped fence lower baffle plate, the piston device is limited to slide below the T-shaped fence upper baffle plate, and the T-shaped fence lower baffle plate limits the piston device to slide in the T-shaped fence above the T-shaped fence lower baffle plate, namely, the piston device is limited to slide in the area between the two baffle plates of the T-shaped fence. The high-pressure and constant-pressure two-section rubber membrane sealing air cabinet is small in pressure fluctuation, large in use space, stable in running, safe, reliable and simple in construction, and can effectively solve the problems that the pressure of the two-section rubber membrane sealing air cabinet is unstable, the T-shaped fence is fixedly clamped, the space of a one-section rubber membrane sealing air cabinet is wasted and the like.