42 results about "Alpha-glucosidase activity" patented technology

The invention relates to the technical field of medicines, and discloses glabrous sarcandra herb acidic polysaccharide quality product SGP-2. The glabrous sarcandra herb acidic polysaccharide is characterized in that the content of polysaccharide is over 90 percent, and the number-average molar mass is 1,000-2,000KDa; monosaccharide comprises glucose, galactose, mannose, arabinose and galacturonic acid; the bond types of glucosidic bond comprise alpha(1->4)galacturonic acid, alpha(1->4) galacturonic acid methyl ester, alpha(1->4) arabinose, alpha(1->4)mannose, beta(1->6) glucose, beta(1->3)galactose, alpha(1->4)glucose, beta (1->4,6)glucose, alpha(1->3,6)galactose, and alpha(1->4,6)galacturonic acid. The invention provides application of the glabrous sarcandra herb acidic polysaccharide quality product SGP-2 in inhibiting alpha-glucosidase activity and application of glabrous sarcandra herb acidic polysaccharide in preparing a medicament for treating diabetes mellitus, and provides application of the glabrous sarcandra herb acidic polysaccharide quality product SGP-2 in preparing anti-tumor medicaments.

The invention discloses a method for extracting an alpha- glucosidase activity inhibitor from plants, which uses whole plants as raw materials, obtains products without toxic and side effect, has high safety and low cost and is suitable to industrial production. The method comprises the following steps of: putting sheared and ground dry branchy tamarisk stem leaves or karelinia caspica stem leaves or reaumuria soongorica stem leaves in an extractor, adding an alcohol-water or acetone-water solution for soaking, wherein the ratio of the volume of the alcohol-water or acetone-water solution to the mass of the dry branchy tamarisk stem leaves or karelinia caspica stem leaves or reaumuria soongorica stem leaves is 8-30 ml / g of, and heating and extracting by backflow, wherein the extracting temperature reaches boiling temperature, the extracting time is 1-3, and the each extraction lasts 1.0-3.0 h; adding water for extracting for the second time, wherein the ratio of the volume of the water to the mass of the extractives is 8-30 ml / g, the extracting temperature reaches boiling temperature, extraction is carried out 1-3 times, and each extraction lasts1.0-3.0 h; collecting and mixing the cooled extractives, concentrating by pressure reduction at 60 DEG C, and finally freezing and drying to obtain the plant extractives.