47 results about "Conjugated Polyelectrolytes" patented technology

Disclosed are a conjugated polyelectrolyte with ratiometric fluorescence signals, a preparation method and an application thereof. The conjugated polyelectrolyte contains more than two chromophores which satisfy fluorescence resonance energy transfer donor and acceptor relationship. The chromophores are associated with each other through Pi-electronic conjugation. The invention also comprises the preparation method of the conjugated polyelectrolyte with ratiometric fluorescence signals and an application thereof. The conjugated polyelectrolyte with ratiometric fluorescence signals has advantages of ratiometric fluorescence signals and conjugated polyelectrolyte, and has strong anti-interference capability, high sensitivity, good selectivity and wide application range.

A method for separation of an aggregated misfolded protein from an environment including a non-aggregating normal form of the protein includes contacting both the misfolded and normal protein with a conjugated polyelectrolyte (CPE) and separating the CPE / protein complex from the other constituents of the sample.

The invention is applicable for the field of a quantum dot light emitting diode (QLED), and provides an indium tin oxide (ITO)-free QLED and a fabrication method thereof. The ITO-free QLED comprises a substrate carrier, a cathode layer, a first non-conjugated polyelectrolyte layer, an electron injection layer, a quantum dot light emitting layer, a hole transfer layer, a hole injection layer and an anode layer which are sequentially laminated, wherein the material of the anode layer is PEDOT:PSS (PH1,000). According to the fabrication method of the ITO-free QLED, the cathode layer, the first non-conjugated polyelectrolyte layer, the electron injection layer, the quantum dot light emitting layer, the hole transfer layer, the hole injection layer and the anode layer are sequentially fabricated on the substrate carrier.

The invention belongs to the technical field of functional polymer film materials, and relates to preparation and application methods of a flexible composite film with a sterilization function. The flexible composite film is prepared by adopting an electrostatic self-assembly technology. The method comprises the steps of firstly preparing a flexible polydimethylsiloxane film; preparing silver nanoparticles by using silver mirror reaction in the flexible film; and adsorbing a polyelectrolyte layer and a fluorescent conjugated polyelectrolyte for sterilization. The flexible composite film has the beneficial effects that the preparation process is simple and convenient, no complicated equipment is needed, the ability of the fluorescent conjugated polyelectrolyte for generating reactive oxygen species is strengthened by the surface plasma effect of the silver nanoparticles in the film; and the film has very good sterilization ability and has good flexibility, and has a good application prospect in the field of food safety and medical hygiene, etc.

The invention discloses a preparation method of an organic optoelectronic device cathode interface layer based on conjugated polyelectrolyte. The method comprises the following steps of (1) preparing an anionic conjugated polyelectrolyte and cationic conjugated polyelectrolyte solutions, (2) carrying out surface processing on a cleaned conductive substrate to obtain a charged substrate, (3) soaking the charged substrate in a conjugated polyelectrolyte solution with opposite charge electrical property, adsorbing a layer of conjugated polyelectrolyte at the charged substrate, and then carrying out washing and drying, (4) soaking the charged substrate in a conjugated polyelectrolyte solution with opposite electrical property of the conjugated polyelectrolyte solution in the step (3), adsorbing a layer of conjugated polyelectrolyte at the charged substrate, and then carrying out washing and drying, and (5) repeating the steps of (3) and (4) to obtain an organic optoelectronic device cathode interface layer. The invention also discloses the application of the organic optoelectronic device cathode interface layer. The preparation method of the invention has the advantages of simple operation and easy control of experimental condition, and the obtained cathode interface layer has efficient cathode interface modification capability.

The present invention relates to conjugated polyelectrolyte (CPE) or oligoelectrolyte (COE) compounds represented by general structural formulae (I)-(IV), or a salt thereof and methods of using these compounds to detect targets in samples. In particular, the methods include: (1) exposing a sample to a compound of structural formula (I), (II) or (IV) or a salt thereof, allowing the compound to bind to a target and detecting a signal produced by the compound; (2) functionalizing a solid support with a ligand, incubating the sample with a charged CPE or COE and detecting the fluorescence of the solid support and thereby detecting the target or (3) functionalizing a surface of a solid support with a charged ligand, thereby creating a charge on the surface of the solid support; incubating the ligand-functionalized solid support with a sample, whereupon binding of the target, the charge on the surface of the solid support switches; incubating the sample with CPE or COE that has a complementary charge to the charge of the target-bound surface; and detecting the fluorescence of the solid support and thereby detecting the target. The compounds of the present invention possess high photoluminescence quantum yields in biological media, low cytotoxicity, and excellent environmental stability and photostability and can be used in biosensor and bioimaging applications.

The invention relates to a method for adjusting fluorescence performance of a conjugate polyelectrolyte. The method comprises the steps of: adding a cyclodextrin water solution in a 1 micromole-10 millimole polyelectrolyte water solution to enable the concentration of cyclodextrin in a mixed solution to achieve 0.1-20 millimole; and under the condition of room temperature, fully mixing the mixed solution, thereby enabling the fluorescence emission wavelength and emission intensity of the polyelectrolyte to change along with the changes of cyclodextrin concentration. According to the method, the fluorescence performance of the conjugate polyelectrolyte is adjusted based on the interaction of host-guest, and the lowering of sensing detection performance of a polymer caused by the formation of a positive-negative ion complex is avoided. Simultaneously, according to the method disclosed by the invention, the fluorescence performance of the polyelectrolyte is adjusted under a pure water state; and the method has the characteristics of simpleness, feasibility, environmental friendliness, and is applicable to preparation of biosensors and chemical sensors, and capable of detecting the sensing of substances such as metal ions.

The invention discloses a novel polythiophene disperse system as well as a preparation method and application thereof, belonging to the field of chemical materials. The novel polythiophene disperse system consists of the following components in parts by mass: 0.01-1.00 part of 3,4-ethylene dioxythiophene, 0.04-14.00 parts of main chain conjugated polyelectrolyte, 0.03-3.30 parts of an oxidant and 40-400 parts of a solvent, wherein a 3,4-ethylene dioxythiophene monomer is subjected to in situ oxidation polymerization in an aqueous solution of the water-soluble main chain conjugated polyelectrolyte to form a blue-black ink-like disperse system. A compact film is formed through slow volatilization of the solvent, thiophene molecules of the film are arranged in parallel and piled along molecular chains of the polyelectrolyte to form a height-oriented crystalline structure, so that the conductivity and stability of the film are obviously improved. The film has an important application prospect in the field of organic electronic devices including polymer photovoltaic cells, organic light-emitting diodes and super-capacitors.

Facile ways towards the development of linear and brush-type zwitterionic conjugated polyelectrolytes possessing hole or electron blocking abilities are presented using combination of polymerization techniques, such as Suzuki or Stille cross coupling, Grignard Metathesis Polymerization and Atom transfer radical polymerization. These zwitterionic conjugated polyelectrolytes will serve as excellent interface materials in various optoelectronic devices.

This invention relates to a sensor that detects bacteria cells comprising (a) a primary negatively charged, nanoparticulate sensing material; (b) a secondary positively charged, fluorescent sensing material; (c) a housing; and (d) at least one illuminator; wherein said housing contains said primary negatively charged, nanoparticulate sensing material, said secondary positively charged fluorescent sensing material and a sample potentially comprising bacteria in aqueous medium, wherein said illuminator provides light of at least one pre-specified wavelength λi to excite at least said secondary positively charged, fluorescent material, wherein said secondary positively charged, fluorescent material electrostatically attached to bacteria cells provides at least one fluorescent response at a second different wavelength λn wherein both i and n are integers, wherein said negatively charged, nanoparticulate sensing material electrostatically attached to said fluorescent material suppresses fluorescing of said fluorescent material at said second wavelength λn; and wherein said housing permits illumination of the contents of said housing by said illuminator and wherein said housing further permits the detection of a fluorescent response at a second wavelength λn. The negatively charged material includes (dsDNA coated) spherical AuNPs and graphene oxide (GO). The positively charged fluorescent material includes water soluble cationic conjugated polyelectrolytes (COPE) or positively charged peptide / polymer labeled with fluorescence dye. The sensor makes use of the FRET phenomenon between the primary and secondary sensing materials. The sensor allows making a distinction between living and dead bacteria and can measure the total bacteria count. A method for detecting bacteria utilizing the sensor is another part of the invention.

A silver ion bactericide has a broad-spectrum antibacterial effect and avoids drug resistance as well as strain variation of microorganisms. Therefore, silver ions are currently an important research direction of the biomedical technology industry. According to the invention, an in-situ synthesis method is adopted for the first time to prepare a conductive conjugate polyelectrolyte / silver halide nanocomposite; and a long-acting broad-spectrum antibacterial effect is realized by adopting a silver halide nanocomposite taking the conductive conjugate polyelectrolyte as a carrier as a broad-spectrum antibacterial material and controlling the size of the silver halide nanoparticles complexed in the conductive conjugate polyelectrolyte to regulate the release rate of silver ions. In the invention, the application of the conductive conjugate polyelectrolyte in biomedicine and particularly the antibacterial field is exploited, and an antibacterial material which avoids toxic and side effects to a human body and is easy to spray and regulate and convenient to use is provided; and the antibacterial material has a broad application prospect in various conduits (catheters and air ducts), dressings and preparations as well as the long-acting mould and bacteria prevention of precise instruments.

The invention belongs to the field of functional material, and discloses a preparation method of a high-dispersity silk fibroin-chitosan-3-methylimidazole salt hexylthiophene-multiwalled carbon nanotube gel. According to the preparation method, the pi-pi bond effect not covalent bond effect of conjugate polyelectrolyte 3-methylimidazole salt hexylthiophene with acidified carbon nanotube surfaces is taken into utilization, so that the mutual attractive force of the modified carbon nanotube is reduced, the adhesiveness of the modified carbon nanotube is reduce, the dispersity is improved, the prepared material is high in stability and hydrophilic performance in solution, preparation speed is accelerated greatly, preparation cost is reduced, no influence on subsequent experiment steps or theperformance of particles to be prepared is caused, experiment result scientific performance is not influenced, experiment operation is simple, nontoxic, and harmless, and the preparation method is green, and is friendly to the environment.

The invention discloses fluorescent conjugated polyelectrolyte with a plurality of carboxyl functional groups, and a preparation method. Polyphenylene ethynylene is used as a conjugated backbone; each repeating unit comprises fours carboxyl functional groups, and a plurality of carboxyl functional groups carried on the side chain thereof are easily coupled with biological molecules; and the polyelectrolyte has good biological compatibility, and is suitable for various biochemistry analysis experiments. The polycarboxyl fluorescent conjugated polyelectrolyte has the advantages of simple operation method, high water solubility and stable fluorescent characteristic. Compared with the other polyphenylene ethynylene polyelectrolyte, the polycarboxyl fluorescent conjugated polyelectrolyte solves the problem of poor solubility of the polymer, also has the advantages of good fluorescent characteristic, high biocompatibility and the like, is a fluorescent sensing material with high comprehensive performance, can be used for high-sensitivity detection of copper ions, and has high selectivity compared with the other materials. The polycarboxyl fluorescent conjugated polyelectrolyte has a structural formula shown in the specification.

The invention relates to a method for separating aggregated misfolded protein from an environment comprising protein in a non-aggregated normal form, which comprises the following steps: using the conjugated polyelectrolyte (CPE) to contact with the misfolded protein and normal protein and separating a CPE / protein complex from other components of a sample.

The invention discloses a synthesis method of an N-type conjugated polyelectrolyte based on an electron deficiency heterocyclic ring main chain. The method provided by the invention solves the problem that the side chain functional groups (i.e., sulfonyl, quaternary ammonium groups and pyridine groups) of nonionic N-type conjugated polymers of electron main chain structures such as diazosulfide and benzotriazole cannot be completely converted into ion functional groups. The synthesis of the copolymerization conjugated polyelectrolytes based on the electron deficiency main chins such as diazosulfide and benzotriazole is realized. The conjugated polyelectrolyte prepared by the method is of an N type; the photoelectric performance is shown by the negative solvation color change effect.

The invention discloses a method for detecting the concentration of persulfate ions by using conjugated polyelectrolyte-silver. The method comprises the following steps of: (1) dissolving conjugated-polyelectrolyte aqueous solution, nanosilver solution and buffering solution in water, after stirring for reaction, obtaining a homogeneous system and measuring fluorescence intensity F0 of the homogeneous system; (2) adding solution containing persulfate ions to be detected into the homogeneous system obtained in the step (1), and after stirring for reaction, measuring fluorescence intensity F ofthe homogeneous system; (3) calculating Y according to a formula Y=(F0-F) / F0, and then obtaining the concentration of the persulfate ions according to a formula expressing the relation between the persulfate ions and the fluorescence intensity, namely Y=0.526*logC(S2O8<2->)+3.044, R=0.955. The method disclosed by the invention is simple and easy in implementation, accurate and rapid, good in selectivity and high in sensitivity, the lowest detection limit is 9*10<-7>mol / L, and the detection linearity in the range of 1*10<-6> to 9*10<-5>mol / L is good.

The invention discloses fluorescent conjugated polyelectrolyte with a plurality of carboxyl functional groups, and a preparation method. Polyphenylene ethynylene is used as a conjugated backbone; each repeating unit comprises fours carboxyl functional groups, and a plurality of carboxyl functional groups carried on the side chain thereof are easily coupled with biological molecules; and the polyelectrolyte has good biological compatibility, and is suitable for various biochemistry analysis experiments. The polycarboxyl fluorescent conjugated polyelectrolyte has the advantages of simple operation method, high water solubility and stable fluorescent characteristic. Compared with the other polyphenylene ethynylene polyelectrolyte, the polycarboxyl fluorescent conjugated polyelectrolyte solves the problem of poor solubility of the polymer, also has the advantages of good fluorescent characteristic, high biocompatibility and the like, is a fluorescent sensing material with high comprehensive performance, can be used for high-sensitivity detection of copper ions, and has high selectivity compared with the other materials. The polycarboxyl fluorescent conjugated polyelectrolyte has a structural formula shown in the specification.

A method for treatment of a disease caused by aggregation of misfolded proteins including subjecting a body fluid of a patient to a separation of an aggregated misfolded protein which includes contacting both the misfolded and normal protein with a conjugated polyelectrolyte (CPE) and separating the CPE / protein complex from the other constituents of the sample.

The invention discloses a flexible organic semiconductor laser and a manufacturing method thereof. A device structure comprises an elastic substrateinterface modification layerorganic semiconductor laser gain medium, wherein the elastic substrate is highly elastic plastic, such as Polydimethylsiloxane (PDMS), polyurethane acrylate (PUA), polyving akohol (PVA), etc.; the interface modification layer is an organic polymer interface modification layer filmed by a solution, such as cellulose acetate (CA), polyelectrolytes (PEs), conjugated polyelectrolytes (CPEs), etc.; the organic semiconductor laser gain medium is a laser material possessing optical characteristics. The manufacturing method comprises coating the interface modification layerorganic semiconductor laser gain medium on the elastic substrate through a solution method, the solution method comprising spin coating, spray coating, silk-screen printing, ink-jet printing, etc. The laser prepared according to the method has excellent combination properties, including low light amplification spontaneous radiation threshold (ASE), and sound flexibility (the threshold maintains stable when the laser is bended and distorted randomly or even stretched).

The invention discloses a quaternary ammonium salt group containing conjugated polyelectrolyte photoelectric material and applications thereof in OLED (organic light emitting diode) devices. Through introducing the quaternary ammonium salt group containing conjugated polyelectrolyte photoelectric material as a hole injection layer material into an OLED device, the performance of the OLED device is greatly improved.

The invention belongs to the technical field of photoelectrode material preparation and photoelectrocatalysis, and particularly relates to preparation and application of an MXene quantum dot activated one-dimensional TiO2 nano composite photoanode. MXene quantum dots, non-conjugated polyelectrolyte PDDA and a one-dimensional TiO2 nanorod array are combined together in an electrostatic layer-by-layer self-assembly mode to form a multi-layer heterojunction photoanode, and is applied to photoelectrocatalytic water decomposition. According to the preparation method, the MXene quantum dots are used for activating the one-dimensional TiO2 nanostructure coated with the polyelectrolyte for the first time, the prepared photoanode has efficient photoelectrocatalysis capacity, and the loading capacity of the MXene quantum dots can be achieved by regulating and controlling the number of self-assembly layers. The whole preparation process is simple, the design principle is reliable, and sustainable development of the environment and energy is facilitated.

The invention belongs to the field of organic semiconductor photoelectric materials, in particular to a hyperbranched conjugated polyelectrolyte based on tripolyindole and a preparation method and anapplication thereof. The invention solves the technical problems in the prior art that the hole transport material based on tripolyindole and its derivatives has poor film forming property, it is difficult to prepare devices by using orthogonal solvent method solution, and the prepared devices have low efficiency. The hyperbranched conjugated polyelectrolyte material based on tripolyindole provided by the invention is neutral in pH and does not corrode corresponding electrodes and organic materials; the hole transport layer of the organic photoelectric device can be prepared by orthogonal solvent method solution processing. It has the advantages of good light transmittance in visible light region and good thermal stability. The hyperbranched conjugated polyelectrolyte based on tripolyindole prepared by the invention is used as a hole transport layer to prepare the organic photovoltaic device or the organic electroluminescent device, and the organic photovoltaic device or the organic electroluminescent device has higher efficiency.

According to the invention, a fluorenyl ion conjugated polyelectrolyte material is mainly used as an interface material and is used between perovskite and a hole transport layer of a perovskite solar cell with an upright structure; the quality of the modified perovskite layer is obviously improved, the grain boundary is reduced, the surface is uniform and regular, and the stability to water and oxygen is obviously improved; and the prepared perovskite layer solar cell has excellent photoelectric conversion efficiency and stability. The potential and wide application prospect of the material in the field of perovskite solar cells is shown; and in the formula, R is 1-16 alkyl straight chains and branched chains.

The invention belongs to the technical field of photoelectrode material preparation and photoelectric catalysis, in particular to a one-dimensional TiO2 activated by MXene quantum dots 2 Preparation and application of nanocomposite photoanode, through electrostatic layer-by-layer self-assembly, makes MXene quantum dots, non-conjugated polyelectrolyte PDDA and one-dimensional TiO 2 The nanorod arrays are combined to form a multilayer heterojunction photoanode and applied to photocatalytic water splitting. The present invention uses MXene quantum dots to activate polyelectrolyte-coated one-dimensional TiO for the first time 2 Nanostructure, the prepared photoanode has efficient photoelectric catalytic ability, and the loading of MXene quantum dots can be realized by adjusting the number of self-assembled layers. The overall preparation process of the invention is simple, the design principle is reliable, and the sustainable development of environment and energy is favorable.

A method for separation of an aggregated misfolded protein from an environment including a non-aggregating normal form of the protein includes contacting both the misfolded and normal protein with a conjugated polyelectrolyte (CPE) and separating the CPE / protein complex from the other constituents of the sample.

The invention discloses a conjugated polyelectrolyte photoelectric material containing amphoteric side chains and an application thereof in an organic light-emitting diode device. The conjugated polyelectrolyte photoelectric material containing the amphoteric side chains provide more choices for hole-injection layer materials of an organic light-emitting diode device, and can be used as the hole-injection layer material having wide application prospects for the organic light-emitting diode device.

The invention discloses a quaternary ammonium salt group containing conjugated polyelectrolyte photoelectric material and applications thereof in OLED (organic light emitting diode) devices. Through introducing the quaternary ammonium salt group containing conjugated polyelectrolyte photoelectric material as a hole injection layer material into an OLED device, the performance of the OLED device is greatly improved.

The invention discloses a conjugated polyelectrolyte photoelectric material containing amphoteric side chains and an application thereof in an OLED (Organic Light Emitting Diode) device. The conjugated polyelectrolyte photoelectric material containing the amphoteric side chains is taken as a hollow injection layer (HIL) material for producing the OLED device; and compared with the performance of a comparison device, the performance of the OLED device is more substantially increased.