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39 results about "Biological media" patented technology
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Biological media, or bio media, is any inert material that houses beneficial bacteria colonies that break down ammonia. Commercial biological media is available in porous rock or pebble-like material, ceramic cylinders, plastic balls, coarse mesh-like material, or even in slab form.
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PendingUS20260034025A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
A apparatus including: a silicone-based body oriented down a central axis, the silicone-based body comprising: a rigid frame having a top axial surface and a bottom axial surface, an outer surface, and a substantially arcuate inner surface; and a plurality of gas-permeable, flexible film membranes connecting the inner surface about a perimeter of the rigid frame at the top axial surface and the bottom axial surface respectively to define an internal void within the body, wherein the rigid frame has a plurality of corrugations along the top axial surface and the bottom axial surface, and wherein the internal void provides for a medically, biologically, chemically, or pharmaceutically active environment.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PendingUS20260028569A1Bioreactor/fermenter combinationsBiological substance pretreatmentsPharmacy medicinePharmaceutical drug
An apparatus including: a core including an annular body defining an internal void oriented down a central axis having a top axial surface and a bottom axial surface; at least one retainer including an annular body adapted to couple to the top axial surface or the bottom axial surface of the core to form a circumferential engagement cavity defined radially between the at least one retainer and the core; at least one ring seal disposed within the engagement cavity; and at least one flexible film membrane partially disposed within the engagement cavity, where the at least one flexible film membrane at least partially encloses the internal void to provide for a medically, biologically, or pharmaceutically active environment within the internal void of the core.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Buried sewage treatment equipment for clean workshop
ActiveCN223316547UTreatment using aerobic processesWater/sewage treatment by irradiationPtru catalystHazardous substance
The utility model relates to the technical field of sewage treatment equipment, and discloses buried sewage treatment equipment for a clean workshop, which comprises a ground, a filtering tank is fixedly connected to the inner wall of the right side of the ground, the right side of the outer wall of the filtering tank is communicated with a water inlet pipe, and a plurality of brackets are connected to the middle upper part of the inner wall of the filtering tank at equal intervals; the adjacent sides of the multiple supports are each rotationally connected with a paddle fan, a blocking plate is fixedly connected to the middle of the inner wall of the filtering tank, multiple reactors are arranged on the inner wall of the blocking plate in a penetrating mode, and an air inlet is formed in the right end of the top wall of the filtering tank. According to the sewage treatment device, sewage to be treated is introduced into the filtering tank, the paddle fan is used for stirring the sewage, the mixing and stirring effects of the sewage are enhanced, a biological medium and a catalyst in the reactor are used for further decomposing and converting harmful substances in the sewage to ensure that the device can efficiently and stably run, and the expected sewage treatment effect is achieved.
Owner:HUBEI UNITED LIGHT IND DESIGN ENG CO LTD
Application of amorphous alloy in field of biological metal materials
The invention relates to the field of biological metal materials, in particular to application of an amorphous alloy in the field of biological metal materials, which comprises the following steps: preparing Zr, Cu, Al, Ag and Fe raw materials, preparing the raw materials into an alloy ingot with the component of Zr50Cu (34-x) FexAl8Ag8 according to atomic percent, putting the alloy ingot into a vacuum non-consumable arc melting furnace for melting, and then suction casting is carried out to prepare the amorphous alloy bar. The amorphous alloy Zr50Cu (34-x) FexAl8Ag8 is applied to be used as a biological metal material. By the adoption of the technical scheme, compared with Zr-Cu-Al-Ag, better corrosion resistance in a biological medium is obtained, and the content of the harmful element Cu in the alloy is reduced.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
Terpolymer and polymer brushes for use against non-specific adsorption of substances from biological media
A random terpolymer of N-(2-hydroxypropyl) methacrylamide, carboxybetaine methacrylamide and sulfobetaine methacrylamide, and a polymer brush and to a functionalized polymer brush containing this terpolymer are disclosed. The random terpolymer increases the resistance of the substrate surface to non-specific adsorption of substances from biological media and / or to non-specific interaction with biological media components, and is suitable for use in the form of a polymer brush, for example in sensors or membranes.
Owner:FYZIKALNI USTAV AV CR V V I
Media delivery system
ActiveCN115492737BPositive displacement pump componentsFlexible member pumpsMicrofluidicsControl theory
The present invention relates to microfluidic technology, and particularly to a medium delivery system. A medium delivery system includes a driving component and a first flow channel. There is a driving medium and a working medium in the first flow channel. There is driving medium at both ends of the first flow channel, and the working medium is located between the driving media; both ends of the second flow channel are located between the two ends of the first flow channel. An inlet and an outlet communicating with an external pipeline are provided in the second flow channel. The working medium flows in the external pipeline. The working medium in the first flow channel and at least one second flow channel can flow along a first preset direction, so that the working medium flows from the inlet to the outlet. The driving component can drive the working medium in the first flow channel to flow in a direction opposite to the first preset direction through the driving medium to return to the initial position. The advantage is that the driving component indirectly drives the working medium through the driving medium, avoiding the mechanical structure in the driving component from damaging the biological medium.
Owner:HANGZHOU DIZHIJING TECHNOLOGY CO LTD
Schistosomiasis transmission risk dynamic simulation method based on data fusion and AI
The invention discloses a schistosomiasis transmission risk dynamic simulation method based on data fusion and AI, and relates to the technical field of intelligent medical treatment. The method comprises the following steps: firstly, collecting environment, biological media, crowd society and intervention measure multi-source heterogeneous data, and unifying the data to a standard spatio-temporal data cube; then data preprocessing is carried out, and feature variables strongly related to propagation risks are constructed; then the processed data and the characteristic variables are input into a risk simulation engine, the engine adopts a hybrid framework in which a mechanism model and an AI prediction model are deeply fused, a dynamic assimilation algorithm is introduced, and risk level maps of different spatial and temporal scales in the future are output; finally, intervention measure scene simulation is carried out based on the risk level map, the cost-benefit ratio is quantitatively evaluated, and an optimal prevention and control strategy suggestion is generated. According to the method, the hysteresis and static defects of a traditional method are overcome, and real-time sensing, dynamic prediction and intelligent decision support of the schistosomiasis transmission risk are achieved.
Owner:JIANGXI INST OF PARASITIC DISEASE CONTROL
Classifying phenotypes and identifying biological mediators from digital histopathology images using deep learning models
PCT designated stageWO2025179049A1Image enhancementMedical data miningPattern recognitionPathology diagnosis
The present disclosure provides methods of training a deep learning (DL)-based classifier to classify a digital histopathology image with respect to a phenotype, methods of classifying a digital histopathology image with respect to a phenotype, and methods of identifying a biological mediator associated with a pathology, pathophysiology, or other clinical characteristic. The disclosure further provides systems for implementation of these methods.
Owner:THE GENERAL HOSPITAL CORP
Bioreactor and bioreactor vessel
PCT designated stageWO2025252989A1Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringMechanics
Bioreactor and a Bioreactor Vessel A rigid-walled bioreactor vessel is provided for containing a biological medium. The vessel includes one or more heat exchange channels for exchanging heat with contents of the vessel. The or each channel is integrated into the wall of the vessel such that the material of the wall also forms the one or more 5 channels. The or each channel has a respective inlet configured to receive a flow of a heat exchange fluid into the channel, and a respective outlet configured to discharge the flow of the heat exchange fluid from the channel
Owner:SARTORIUS STEDIM BIOTECH GMBH
Bioreactor including probe for electrical or electromagnetic measurements
ActiveUS12624331B2Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringBioreactor
A bioreactor includes a rigid-walled vessel for containing a biological medium, the vessel having a lid. The bioreactor further includes a probe passing through an aperture in the lid and having a sensing end inside the vessel and a remote end outside the vessel. The sensing end has plural electrodes for immersion in the biological medium, and the remote end is configured for coupling to external devices and transmission thereto of electrical or electromagnetic measurements made by the electrodes. One of the lid and the probe has one or more resiliently deformable mechanisms and the other of the lid and the probe has one or more respective complementary surfaces. The resiliently deformable mechanisms and the complementary surfaces are configured such that, on insertion of the probe through the aperture to assemble the probe to the lid, the one or more resiliently deformable mechanisms are first deformed on sliding against the one or more complementary surfaces and then resile when the probe reaches a predetermined insertion position relative to the lid to secure the probe to the lid. One of the lid and the probe carries a sealing element which seals the probe to the lid when the probe is secured at the predetermined position.
Owner:THE AUTOMATION PARTNERSHIP (CAMBRIDGE) LTD
Bioreactor system with gassing installation
PendingUS20260035649A1Bioreactor/fermenter combinationsBiological substance pretreatmentsProcess engineeringMaster controller
A bioreactor system for carrying out a biological process including a vessel for receiving a liquid biological medium, and a gassing installation for controlled supply of different gases from gas sources into the vessel. The gassing installation has a plurality of gas outlet lines which open into gassing devices and / or into an overlay gas outlet in the interior of the vessel. Each gas outlet line is connected to a plurality of gas sources via a respective gas supply line or via a respective branch from a gas supply line. A mass flow controller connected to a controller is arranged in each gas supply line and in each branch. The system may include a controller with a master controller for a controlled variable, at least one sensor associated with the master controller, and one or more slave controllers having actuators, the manipulated variables of which purposefully influence the controlled variable.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PCT designated stageWO2026024819A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
An apparatus including: a core including an annular body defining an internal void oriented down a central axis having a top axial surface and a bottom axial surface; at least one retainer including an annular body adapted to couple to the top axial surface or the bottom axial surface of the core to form a circumferential engagement cavity defined radially between the at least one retainer and the core; at least one ring seal disposed within the engagement cavity; and at least one flexible film membrane partially disposed within the engagement cavity, where the at least one flexible film membrane at least partially encloses the internal void to provide for a medically, biologically, or pharmaceutically active environment within the internal void of the core.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Electrochemical capacitive biofouling resistant biosensors and methods of making and using same
Described herein are electrochemical capacitive biosensors, methods of making same, and methods of using same. The electrochemical capacitive biosensors are especially useful for detecting pathogens, including viruses, bacteria, and allergens, in aerosols and complex biological media.
Owner:WASHINGTON UNIV IN SAINT LOUIS
Method for determining the viscoelastic properties of a biological medium, module and associated device
PendingFR3167053A1Ultrasonic/sonic/infrasonic diagnosticsInfrasonic diagnosticsMechanical engineeringMechanics
The invention relates to a module for determining the viscoelastic properties, referred to as the module, of a moving biological medium of variable thickness, referred to as the medium, at least partially enclosed in an elastic biological environment. The module comprises a processing unit arranged to calculate, from propagation data of at least one shear wave in the medium, a dispersion curve of the at least one shear wave in the medium, and to determine, from the dispersion curve of the at least one shear wave in the medium and a propagation mode of the at least one shear wave in the medium, a thickness of the medium and / or the viscoelastic properties of the medium. Figure for the abstract: FIGURE 3
Owner:UNIV PARIS SACLAY +4
Preparation method of 3D cell culture body based on sacrificial material, 3D cell culture body and application
The invention discloses a preparation method of a 3D cell culture body. The preparation method comprises the following steps: (A) constructing a framework based on a sacrificial material; (B) arranging a first culture cell and a curable biological medium around the skeleton, and then curing the biological medium to form a cured biological medium block; (C) covering the biological medium block with a curable packaging material, then curing the packaging material, and forming a packaging layer on the outer side of the biological medium block; and (D) removing the skeleton so as to form a perfusion structure in the biological medium block, thereby obtaining the 3D cell culture body.
Owner:SUZHOU XIANJUE BIOTECHNOLOGY CO LTD
Fluorescent biosensing analysis device and method
Femtosecond pulse near-infrared Gaussian laser is adopted as a unified light source and is simultaneously used for time-sharing scanning optical tweezers capturing and two-photon fluorescence excitation, and a light path part is sequentially provided with a height adjusting assembly, a galvanometer scanning element, a beam expanding assembly and a telescope assembly. The light is reflected by a dichroscope configured on an inverted microscope platform, strong focusing is realized in a PDMS sample chamber by a high numerical aperture objective lens, bright field illumination is provided by a white light LED lamp, and a two-photon fluorescence signal is collected by a CMOS camera; a high-precision biosensing system based on a CRISPR / Cas12a system is constructed on the surface of a microsphere enriched with a detection signal output unit, quenching-recovery conversion of a fluorescence signal is realized, and two-photon fluorescence imaging is carried out in a multiple optical capture microsphere array formed by time-sharing scanning optical tweezers. The method has the advantages of high detection accuracy and sensitivity, low background signal, good imaging stability, strong anti-interference capability in a complex biological medium and the like.
Owner:WUHAN UNIV OF SCI & TECH
Electrochemical capacitive biofouling resistant biosensors and methods of making and using same
PCT designated stageWO2026090101A3Material capacitanceMaterial electrochemical variablesEngineeringBiofouling
Described herein are electrochemical capacitive biosensors, methods of making same, and methods of using same. The electrochemical capacitive biosensors are especially useful for detecting pathogens, including viruses, bacteria, and allergens, in aerosols and complex biological media.
Owner:WASHINGTON UNIV IN SAINT LOUIS
System and method for cleaning a bioreactor
PCT designated stageWO2026090725A1Sludge treatmentSpecific water treatment objectivesSludgeWastewater
A system, a kit, and a method of cleaning a bioreactor in which wastewater is treated, the bioreactor housing biomedia in suspension in the wastewater. The method includes withdrawing at least some of the wastewater from the bioreactor into a separator. The wastewater includes a mixture of sludge and water. The method further includes processing the withdrawn wastewater to separate at least some of the sludge from water. The method further includes returning at least some of the processed wastewater from the external housing to the bioreactor, the processed wastewater having a lower sludge content than the sludge content in the wastewater of the bioreactor before it was processed.
Owner:TECH BIONEST INC
Biosensor based on graphene bilayer gate tunneling field effect transistor
The application relates to the field of biosensors, and particularly relates to a biosensor based on a graphene double-material gate tunneling field effect transistor, which comprises a graphene channel, a source electrode, a drain electrode, an insulating medium layer, a silicon substrate, a gate medium layer, a first gate electrode, a second gate electrode, a biological medium layer and a biological nanocavity; the silicon substrate, the insulating medium layer, the graphene channel and the gate medium layer are sequentially stacked from bottom to top; the source electrode and the drain electrode are located on the left and right sides of the graphene channel; the biological medium layer and the second gate electrode are respectively stacked on the left and right end portions of the upper surface of the gate medium layer, and the biological medium layer is hollow to form the biological nanocavity; the first gate electrode is stacked on the upper surface of the biological medium layer; the work functions of the metal materials of the first gate electrode and the second gate electrode are different. The application can comprehensively control the energy band of the graphene channel, can realize energy band tunneling between the graphene without doping the graphene, has a relatively simple manufacturing process, and has high sensitivity.
Owner:CHANGZHOU UNIV
Surface processing method for medical metal instruments with anti-adhesion property
This invention discloses a method for surface processing of medical metal instruments with anti-adhesion properties, comprising the following steps: S1, pretreating the substrate surface of the medical metal instrument; S2, using a femtosecond laser to scan and etch the pretreated substrate surface to construct a biomimetic microtexture with micron-level structural features and nanometer-level roughness; S3, immersing the surface treated in step S2 in a stearic acid-ethanol solution for chemical modification to form a hydrophobic molecular layer on the surface of the biomimetic microtexture, thereby obtaining a superhydrophobic anti-adhesion surface. This invention can stably construct biomimetic micro / nanostructures with excellent superhydrophobic properties on the surface of medical metal instruments, thereby significantly reducing the adhesion of biological media such as blood and tissue, improving surgical efficiency and instrument lifespan.
Owner:INST OF LASER & OPTOELECTRONICS INTELLIGENT MFG WENZHOU UNIV
Alternating charges to inhibit adsorption to surfaces exposed to biological materials
A system and / or method is disclosed to suppress adsorption and / or biofouling on a surface in a biological medium by means of an alternating electric field. For example, one or more insulating electrodes may be disposed near the surface. For example, insulation may limit the current between the biological medium and the electrodes, and / or between the surface and the electrodes, and / or between the plurality of electrodes. In some embodiments, the alternating charge near the surface may suppress the accumulation of multiple biofilms and / or adsorption onto the surface. For example, the system may be used to suppress fouling of an implantable medical device (e.g., a catheter).
Owner:RAMBAM MEDTECH LTD +2
Bioprocessing installation
ActiveUS12637654B2Bioreactor/fermenter combinationsBiological substance pretreatmentsLiquid stateControl cell
A bioprocessing installation comprising a reservoir tank, one or more fluid lines, one or more receiving containers and an electronic control unit. The fluid line fluidically connects the reservoir tank to a receiving container. The liquid biological medium can be transferred from the reservoir tank through the fluid line into the at least one receiving container. The bioprocessing installation comprises a sensor arrangement with at least one gas bubble sensor, which sensor arrangement is configured to detect one or more gas bubbles or foam or separated phases in the liquid biological medium by a gas bubble sensor and to generate one or more corresponding sensor signals, and the electronic control unit is configured to monitor the transfer of the liquid biological medium from the reservoir tank in the direction of the at least one receiving container based on the sensor signals generated by the sensor arrangement.
Owner:SARTORIUS STEDIM BIOTECH GMBH
MXene (at) Au photo-thermal nano motor as well as preparation method and application thereof
The invention belongs to the technical field of nano motors, and particularly relates to an MXene (at) Au photo-thermal nano motor and a preparation method and application thereof. The MXene (at) Au composite nano motor provided by the invention comprises a modified single-layer MXene nanosheet and an active component loaded on the surface of the modified single-layer MXene nanosheet, the active component is a gold nano-cluster coated with bovine serum albumin; the modified single-layer MXene nanosheet is obtained by modifying with a cationic surface active agent; the loading is realized through an electrostatic adsorption effect. The MXene (at) Au nano motor provided by the invention generates an asymmetric thermal gradient under illumination to drive the nano motor to realize self-propelling movement in a solution, so that the diffusion efficiency and the A beta targeted enrichment capacity in a complex biological medium can be remarkably enhanced, and further efficient recognition and photo-thermal degradation of A beta protein aggregates are realized.
Owner:JINAN UNIVERSITY
Bioreactor, bioreactor vessel and closure component for a bioreactor vessel
PCT designated stageWO2025252988A1Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringMechanics
Bioreactor, a Bioreactor Vessel and a Closure Component for a Bioreactor Vessel A closure component is provided for closing an upper opening of a rigid-walled bioreactor vessel, in use the vessel containing a biological medium and the upper opening providing access to the interior of the vessel. The component has: a lid having a mounting for fixing to a rim of the upper opening such that the lid closes the upper opening; a shaft which extends downwards from the lid; and one or more impellers mounted to the shaft. The mounting forms a bearing with the rim of the opening when fixed thereto. The lid, the shaft and the one or more impellers are integrally formed such that the component is a one-piece assembly in which the lid, the shaft and the one or more impellers are rotatable together as a single unit to stir the contents of the vessel.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Alternating charge to inhibit sorption to surfaces exposed to biological materials
A system and / or method are disclosed to inhibit sorption to a surface in a biological medium and / or biofouling by means of an alternating electric field. For example, one or more insulated electrodes may be positioned near the surface. For example, insulation may limit electric current flow between the biological medium and the electrode and / or between the surface and the electrode and / or between the electrodes. In some embodiments, the alternating charge in the vicinity of the surface may inhibit the buildup of biological films and / or sorption to the surface. For example, the system may be used to inhibit fouling of an implanted medical device (e.g. a catheter).
Owner:RAMBAM MEDTECH LTD
Sensor positioning system for a bioprocess engineering installation
ActiveUS12478970B2Bioreactor/fermenter combinationsBiological substance pretreatmentsBioprocess engineeringPositioning aids
A sensor positioning system for a bioprocess engineering unit, wherein a container is provided for receiving a biological medium which, when installed, extends in the axial direction from an upper container end to a lower container end, wherein a holder is provided for holding the container when installed, wherein a sensor is provided for fixing to the container. A positioning aid device for positioning the sensor to be fixed is provided on the container, the positioning aid device has a positioning aid that can be applied directly to or near the container on the holder, which can be brought into different vertical positions and / or circumferential positions relative to at least one reference point provided on the container and / or holder, and the positioning aid device has a technical storage medium or analog print medium with an allocation list.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Anti-blocking biological medium separation equipment
ActiveCN224220864USustainable biological treatmentStationary filtering element filtersControl theoryMechanical engineering
Owner:SHENYANG ANYUEXI TECHNOLOGY CO LTD
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PCT designated stageWO2026030573A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
A apparatus including: a silicone-based body oriented down a central axis, the silicone-based body comprising: a rigid frame having a top axial surface and a bottom axial surface, an outer surface, and a substantially arcuate inner surface; and a plurality of gas-permeable, flexible film membranes connecting the inner surface about a perimeter of the rigid frame at the top axial surface and the bottom axial surface respectively to define an internal void within the body, wherein the rigid frame has a plurality of corrugations along the top axial surface and the bottom axial surface, and wherein the internal void provides for a medically, biologically, chemically, or pharmaceutically active environment.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Shortfall quantity liquid container
A small-volume liquid container for dispensing a liquid medium, especially biological medium, into a bioprocessing system, especially into a bioreactor, wherein the liquid container provides an accommodation volume for the liquid medium, wherein the liquid container comprises two dimensionally stable container parts, which are movable relative to one another between an initial position and an end position, and an outlet connection for discharge of the liquid medium. It is proposed that the liquid container comprises a shape-changeable delimitation means which at least sectionally delimits the accommodation volume and which is connected to the dimensionally stable container parts in such a way that a relative movement of the dimensionally stable container parts to one another, causing a change in volume of the accommodation volume, is associated with a change in shape of the delimitation means.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Method for determining viscoelastic properties of a biological medium, associated module and device
PCT designated stageWO2026074124A1Organ movement/changes detectionUltrasonic/sonic/infrasonic dianostic techniquesMechanical engineeringMechanics
The invention relates to a module for determining viscoelastic properties, referred to as the module, of a moving biological medium of variable thickness, referred to as the medium, which is at least partially enclosed in an elastic biological environment. The module comprises a processing unit arranged to calculate a dispersion curve of the at least one shear wave in the medium, based on data relating to the propagation of at least one shear wave in the medium, and to determine a thickness of the medium and / or the viscoelastic properties of the medium, based on the dispersion curve of the at least one shear wave in the medium and a mode of propagation of the at least one shear wave in the medium.
Owner:UNIV PARIS SACLAY +4