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28 results about "Biological media" patented technology
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Biological media, or bio media, is any inert material that houses beneficial bacteria colonies that break down ammonia. Commercial biological media is available in porous rock or pebble-like material, ceramic cylinders, plastic balls, coarse mesh-like material, or even in slab form.
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PendingUS20260034025A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
A apparatus including: a silicone-based body oriented down a central axis, the silicone-based body comprising: a rigid frame having a top axial surface and a bottom axial surface, an outer surface, and a substantially arcuate inner surface; and a plurality of gas-permeable, flexible film membranes connecting the inner surface about a perimeter of the rigid frame at the top axial surface and the bottom axial surface respectively to define an internal void within the body, wherein the rigid frame has a plurality of corrugations along the top axial surface and the bottom axial surface, and wherein the internal void provides for a medically, biologically, chemically, or pharmaceutically active environment.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PendingUS20260028569A1Bioreactor/fermenter combinationsBiological substance pretreatmentsPharmacy medicinePharmaceutical drug
An apparatus including: a core including an annular body defining an internal void oriented down a central axis having a top axial surface and a bottom axial surface; at least one retainer including an annular body adapted to couple to the top axial surface or the bottom axial surface of the core to form a circumferential engagement cavity defined radially between the at least one retainer and the core; at least one ring seal disposed within the engagement cavity; and at least one flexible film membrane partially disposed within the engagement cavity, where the at least one flexible film membrane at least partially encloses the internal void to provide for a medically, biologically, or pharmaceutically active environment within the internal void of the core.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Schistosomiasis transmission risk dynamic simulation method based on data fusion and AI
The invention discloses a schistosomiasis transmission risk dynamic simulation method based on data fusion and AI, and relates to the technical field of intelligent medical treatment. The method comprises the following steps: firstly, collecting environment, biological media, crowd society and intervention measure multi-source heterogeneous data, and unifying the data to a standard spatio-temporal data cube; then data preprocessing is carried out, and feature variables strongly related to propagation risks are constructed; then the processed data and the characteristic variables are input into a risk simulation engine, the engine adopts a hybrid framework in which a mechanism model and an AI prediction model are deeply fused, a dynamic assimilation algorithm is introduced, and risk level maps of different spatial and temporal scales in the future are output; finally, intervention measure scene simulation is carried out based on the risk level map, the cost-benefit ratio is quantitatively evaluated, and an optimal prevention and control strategy suggestion is generated. According to the method, the hysteresis and static defects of a traditional method are overcome, and real-time sensing, dynamic prediction and intelligent decision support of the schistosomiasis transmission risk are achieved.
Owner:JIANGXI INST OF PARASITIC DISEASE CONTROL
Bioreactor and bioreactor vessel
PCT designated stageWO2025252989A1Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringMechanics
Bioreactor and a Bioreactor Vessel A rigid-walled bioreactor vessel is provided for containing a biological medium. The vessel includes one or more heat exchange channels for exchanging heat with contents of the vessel. The or each channel is integrated into the wall of the vessel such that the material of the wall also forms the one or more 5 channels. The or each channel has a respective inlet configured to receive a flow of a heat exchange fluid into the channel, and a respective outlet configured to discharge the flow of the heat exchange fluid from the channel
Owner:SARTORIUS STEDIM BIOTECH GMBH
Bioreactor including probe for electrical or electromagnetic measurements
ActiveUS12624331B2Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringBioreactor
A bioreactor includes a rigid-walled vessel for containing a biological medium, the vessel having a lid. The bioreactor further includes a probe passing through an aperture in the lid and having a sensing end inside the vessel and a remote end outside the vessel. The sensing end has plural electrodes for immersion in the biological medium, and the remote end is configured for coupling to external devices and transmission thereto of electrical or electromagnetic measurements made by the electrodes. One of the lid and the probe has one or more resiliently deformable mechanisms and the other of the lid and the probe has one or more respective complementary surfaces. The resiliently deformable mechanisms and the complementary surfaces are configured such that, on insertion of the probe through the aperture to assemble the probe to the lid, the one or more resiliently deformable mechanisms are first deformed on sliding against the one or more complementary surfaces and then resile when the probe reaches a predetermined insertion position relative to the lid to secure the probe to the lid. One of the lid and the probe carries a sealing element which seals the probe to the lid when the probe is secured at the predetermined position.
Owner:THE AUTOMATION PARTNERSHIP (CAMBRIDGE) LTD
Bioreactor system with gassing installation
PendingUS20260035649A1Bioreactor/fermenter combinationsBiological substance pretreatmentsProcess engineeringMaster controller
A bioreactor system for carrying out a biological process including a vessel for receiving a liquid biological medium, and a gassing installation for controlled supply of different gases from gas sources into the vessel. The gassing installation has a plurality of gas outlet lines which open into gassing devices and / or into an overlay gas outlet in the interior of the vessel. Each gas outlet line is connected to a plurality of gas sources via a respective gas supply line or via a respective branch from a gas supply line. A mass flow controller connected to a controller is arranged in each gas supply line and in each branch. The system may include a controller with a master controller for a controlled variable, at least one sensor associated with the master controller, and one or more slave controllers having actuators, the manipulated variables of which purposefully influence the controlled variable.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PCT designated stageWO2026024819A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
An apparatus including: a core including an annular body defining an internal void oriented down a central axis having a top axial surface and a bottom axial surface; at least one retainer including an annular body adapted to couple to the top axial surface or the bottom axial surface of the core to form a circumferential engagement cavity defined radially between the at least one retainer and the core; at least one ring seal disposed within the engagement cavity; and at least one flexible film membrane partially disposed within the engagement cavity, where the at least one flexible film membrane at least partially encloses the internal void to provide for a medically, biologically, or pharmaceutically active environment within the internal void of the core.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Electrochemical capacitive biofouling resistant biosensors and methods of making and using same
Described herein are electrochemical capacitive biosensors, methods of making same, and methods of using same. The electrochemical capacitive biosensors are especially useful for detecting pathogens, including viruses, bacteria, and allergens, in aerosols and complex biological media.
Owner:WASHINGTON UNIV IN SAINT LOUIS
Method for determining the viscoelastic properties of a biological medium, module and associated device
PendingFR3167053A1Ultrasonic/sonic/infrasonic diagnosticsInfrasonic diagnosticsMechanical engineeringMechanics
The invention relates to a module for determining the viscoelastic properties, referred to as the module, of a moving biological medium of variable thickness, referred to as the medium, at least partially enclosed in an elastic biological environment. The module comprises a processing unit arranged to calculate, from propagation data of at least one shear wave in the medium, a dispersion curve of the at least one shear wave in the medium, and to determine, from the dispersion curve of the at least one shear wave in the medium and a propagation mode of the at least one shear wave in the medium, a thickness of the medium and / or the viscoelastic properties of the medium. Figure for the abstract: FIGURE 3
Owner:UNIV PARIS SACLAY +4
Fluorescent biosensing analysis device and method
Femtosecond pulse near-infrared Gaussian laser is adopted as a unified light source and is simultaneously used for time-sharing scanning optical tweezers capturing and two-photon fluorescence excitation, and a light path part is sequentially provided with a height adjusting assembly, a galvanometer scanning element, a beam expanding assembly and a telescope assembly. The light is reflected by a dichroscope configured on an inverted microscope platform, strong focusing is realized in a PDMS sample chamber by a high numerical aperture objective lens, bright field illumination is provided by a white light LED lamp, and a two-photon fluorescence signal is collected by a CMOS camera; a high-precision biosensing system based on a CRISPR / Cas12a system is constructed on the surface of a microsphere enriched with a detection signal output unit, quenching-recovery conversion of a fluorescence signal is realized, and two-photon fluorescence imaging is carried out in a multiple optical capture microsphere array formed by time-sharing scanning optical tweezers. The method has the advantages of high detection accuracy and sensitivity, low background signal, good imaging stability, strong anti-interference capability in a complex biological medium and the like.
Owner:WUHAN UNIV OF SCI & TECH
Electrochemical capacitive biofouling resistant biosensors and methods of making and using same
PCT designated stageWO2026090101A3Material capacitanceMaterial electrochemical variablesEngineeringBiofouling
Described herein are electrochemical capacitive biosensors, methods of making same, and methods of using same. The electrochemical capacitive biosensors are especially useful for detecting pathogens, including viruses, bacteria, and allergens, in aerosols and complex biological media.
Owner:WASHINGTON UNIV IN SAINT LOUIS
System and method for cleaning a bioreactor
PCT designated stageWO2026090725A1Sludge treatmentSpecific water treatment objectivesSludgeWastewater
A system, a kit, and a method of cleaning a bioreactor in which wastewater is treated, the bioreactor housing biomedia in suspension in the wastewater. The method includes withdrawing at least some of the wastewater from the bioreactor into a separator. The wastewater includes a mixture of sludge and water. The method further includes processing the withdrawn wastewater to separate at least some of the sludge from water. The method further includes returning at least some of the processed wastewater from the external housing to the bioreactor, the processed wastewater having a lower sludge content than the sludge content in the wastewater of the bioreactor before it was processed.
Owner:TECH BIONEST INC
Biosensor based on graphene bilayer gate tunneling field effect transistor
The application relates to the field of biosensors, and particularly relates to a biosensor based on a graphene double-material gate tunneling field effect transistor, which comprises a graphene channel, a source electrode, a drain electrode, an insulating medium layer, a silicon substrate, a gate medium layer, a first gate electrode, a second gate electrode, a biological medium layer and a biological nanocavity; the silicon substrate, the insulating medium layer, the graphene channel and the gate medium layer are sequentially stacked from bottom to top; the source electrode and the drain electrode are located on the left and right sides of the graphene channel; the biological medium layer and the second gate electrode are respectively stacked on the left and right end portions of the upper surface of the gate medium layer, and the biological medium layer is hollow to form the biological nanocavity; the first gate electrode is stacked on the upper surface of the biological medium layer; the work functions of the metal materials of the first gate electrode and the second gate electrode are different. The application can comprehensively control the energy band of the graphene channel, can realize energy band tunneling between the graphene without doping the graphene, has a relatively simple manufacturing process, and has high sensitivity.
Owner:CHANGZHOU UNIV
Surface processing method for medical metal instruments with anti-adhesion property
This invention discloses a method for surface processing of medical metal instruments with anti-adhesion properties, comprising the following steps: S1, pretreating the substrate surface of the medical metal instrument; S2, using a femtosecond laser to scan and etch the pretreated substrate surface to construct a biomimetic microtexture with micron-level structural features and nanometer-level roughness; S3, immersing the surface treated in step S2 in a stearic acid-ethanol solution for chemical modification to form a hydrophobic molecular layer on the surface of the biomimetic microtexture, thereby obtaining a superhydrophobic anti-adhesion surface. This invention can stably construct biomimetic micro / nanostructures with excellent superhydrophobic properties on the surface of medical metal instruments, thereby significantly reducing the adhesion of biological media such as blood and tissue, improving surgical efficiency and instrument lifespan.
Owner:INST OF LASER & OPTOELECTRONICS INTELLIGENT MFG WENZHOU UNIV
Bioprocessing installation
ActiveUS12637654B2Bioreactor/fermenter combinationsBiological substance pretreatmentsLiquid stateControl cell
A bioprocessing installation comprising a reservoir tank, one or more fluid lines, one or more receiving containers and an electronic control unit. The fluid line fluidically connects the reservoir tank to a receiving container. The liquid biological medium can be transferred from the reservoir tank through the fluid line into the at least one receiving container. The bioprocessing installation comprises a sensor arrangement with at least one gas bubble sensor, which sensor arrangement is configured to detect one or more gas bubbles or foam or separated phases in the liquid biological medium by a gas bubble sensor and to generate one or more corresponding sensor signals, and the electronic control unit is configured to monitor the transfer of the liquid biological medium from the reservoir tank in the direction of the at least one receiving container based on the sensor signals generated by the sensor arrangement.
Owner:SARTORIUS STEDIM BIOTECH GMBH
MXene (at) Au photo-thermal nano motor as well as preparation method and application thereof
The invention belongs to the technical field of nano motors, and particularly relates to an MXene (at) Au photo-thermal nano motor and a preparation method and application thereof. The MXene (at) Au composite nano motor provided by the invention comprises a modified single-layer MXene nanosheet and an active component loaded on the surface of the modified single-layer MXene nanosheet, the active component is a gold nano-cluster coated with bovine serum albumin; the modified single-layer MXene nanosheet is obtained by modifying with a cationic surface active agent; the loading is realized through an electrostatic adsorption effect. The MXene (at) Au nano motor provided by the invention generates an asymmetric thermal gradient under illumination to drive the nano motor to realize self-propelling movement in a solution, so that the diffusion efficiency and the A beta targeted enrichment capacity in a complex biological medium can be remarkably enhanced, and further efficient recognition and photo-thermal degradation of A beta protein aggregates are realized.
Owner:JINAN UNIVERSITY
Bioreactor, bioreactor vessel and closure component for a bioreactor vessel
PCT designated stageWO2025252988A1Bioreactor/fermenter combinationsBiological substance pretreatmentsMechanical engineeringMechanics
Bioreactor, a Bioreactor Vessel and a Closure Component for a Bioreactor Vessel A closure component is provided for closing an upper opening of a rigid-walled bioreactor vessel, in use the vessel containing a biological medium and the upper opening providing access to the interior of the vessel. The component has: a lid having a mounting for fixing to a rim of the upper opening such that the lid closes the upper opening; a shaft which extends downwards from the lid; and one or more impellers mounted to the shaft. The mounting forms a bearing with the rim of the opening when fixed thereto. The lid, the shaft and the one or more impellers are integrally formed such that the component is a one-piece assembly in which the lid, the shaft and the one or more impellers are rotatable together as a single unit to stir the contents of the vessel.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Sensor positioning system for a bioprocess engineering installation
ActiveUS12478970B2Bioreactor/fermenter combinationsBiological substance pretreatmentsBioprocess engineeringPositioning aids
A sensor positioning system for a bioprocess engineering unit, wherein a container is provided for receiving a biological medium which, when installed, extends in the axial direction from an upper container end to a lower container end, wherein a holder is provided for holding the container when installed, wherein a sensor is provided for fixing to the container. A positioning aid device for positioning the sensor to be fixed is provided on the container, the positioning aid device has a positioning aid that can be applied directly to or near the container on the holder, which can be brought into different vertical positions and / or circumferential positions relative to at least one reference point provided on the container and / or holder, and the positioning aid device has a technical storage medium or analog print medium with an allocation list.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Anti-blocking biological medium separation equipment
ActiveCN224220864USustainable biological treatmentStationary filtering element filtersControl theoryMechanical engineering
Owner:SHENYANG ANYUEXI TECHNOLOGY CO LTD
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
PCT designated stageWO2026030573A1Pharmaceutical containersMedical packagingPharmacy medicinePharmaceutical drug
A apparatus including: a silicone-based body oriented down a central axis, the silicone-based body comprising: a rigid frame having a top axial surface and a bottom axial surface, an outer surface, and a substantially arcuate inner surface; and a plurality of gas-permeable, flexible film membranes connecting the inner surface about a perimeter of the rigid frame at the top axial surface and the bottom axial surface respectively to define an internal void within the body, wherein the rigid frame has a plurality of corrugations along the top axial surface and the bottom axial surface, and wherein the internal void provides for a medically, biologically, chemically, or pharmaceutically active environment.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Shortfall quantity liquid container
A small-volume liquid container for dispensing a liquid medium, especially biological medium, into a bioprocessing system, especially into a bioreactor, wherein the liquid container provides an accommodation volume for the liquid medium, wherein the liquid container comprises two dimensionally stable container parts, which are movable relative to one another between an initial position and an end position, and an outlet connection for discharge of the liquid medium. It is proposed that the liquid container comprises a shape-changeable delimitation means which at least sectionally delimits the accommodation volume and which is connected to the dimensionally stable container parts in such a way that a relative movement of the dimensionally stable container parts to one another, causing a change in volume of the accommodation volume, is associated with a change in shape of the delimitation means.
Owner:SARTORIUS STEDIM BIOTECH GMBH
Method for determining viscoelastic properties of a biological medium, associated module and device
PCT designated stageWO2026074124A1Organ movement/changes detectionUltrasonic/sonic/infrasonic dianostic techniquesMechanical engineeringMechanics
The invention relates to a module for determining viscoelastic properties, referred to as the module, of a moving biological medium of variable thickness, referred to as the medium, which is at least partially enclosed in an elastic biological environment. The module comprises a processing unit arranged to calculate a dispersion curve of the at least one shear wave in the medium, based on data relating to the propagation of at least one shear wave in the medium, and to determine a thickness of the medium and / or the viscoelastic properties of the medium, based on the dispersion curve of the at least one shear wave in the medium and a mode of propagation of the at least one shear wave in the medium.
Owner:UNIV PARIS SACLAY +4
Heat preservation system for sewage treatment facility in high-cold and high-altitude highway service area
ActiveCN224160474UCesspoolsFatty/oily/floating substances removal devicesThermodynamicsHeat conservation
The utility model relates to the field of sewage treatment in service areas, in particular to a heat preservation system for sewage treatment facilities in high-cold and high-altitude highway service areas, which comprises a heat preservation layer: a strake is wound on the surface of the heat preservation layer, two ends of the strake are fixedly connected with a frame box body and a rack respectively, and the bottom of the frame box body is fixedly connected with a rectangular box through bolts; the inner wall of the frame box body is rotationally connected with a rotating rod, and the frame box body and the rack are tensioned through meshing of the rack and the gear, so that the heat preservation layer is tightly hooped on the surface of the biological medium filter tank through the hooping strip; the heat preservation layer can be arranged on the surface of the sewage treatment pool in the highway service area in the high-cold and high-altitude area, and heat exchange between the pool body and the outside is isolated through the heat preservation layer, so that the influence of the outside low temperature on the temperature in the sewage treatment pool is reduced, and the purposes of improving the economical efficiency and the treatment effect of the biological medium sewage treatment pool are achieved.
Owner:CHINA ACAD OF TRANSPORTATION SCI +1
Apparatus, system, and method for storing medical, pharmaceutical, or biological media
An apparatus including: a core including an annular body defining an internal void oriented down a central axis having a top axial surface and a bottom axial surface; at least one retainer including a body adapted to couple to the top axial surface or the bottom axial surface of the core; and at least one flexible film membrane bonded to the at least one retainer, where the at least one flexible film membrane at least partially encloses the internal void to provide for a medically, biologically, or pharmaceutically active environment within the internal void of the core, where the at least one retainer includes a rigid inner portion including a plurality of through holes, where the at least one retainer is adapted to hold the at least one flexible film membrane in a substantially static axial position.
Owner:SAINT GOBAIN PERFORMANCE PLASTICS CORP
Method for preparing 3D cell culture construct on basis of sacrificial material, and 3D cell culture construct and use thereof
Disclosed in the present invention is a method for preparing a 3D cell culture construct on the basis of a sacrificial material, which method comprises the following steps: (A) constructing a scaffold on the basis of a sacrificial material; (B) configuring a first culture cell and a curable biological medium around the scaffold, and then curing the biological medium to form a cured biological medium block; (C) covering the biological medium block with a curable encapsulating material, and then curing the encapsulating material to form an encapsulating layer on the outer side of the biological medium block; and (D) removing the scaffold, thereby forming a perfusion structure inside the biological medium block to obtain the 3D cell culture body.
Owner:SUZHOU XIANJUE BIOTECHNOLOGY CO LTD
Photo-acid-driven single-hole colloid motor and preparation method thereof
The invention discloses a photo-acid-driven single-hole colloid motor and a preparation method thereof, and belongs to the field of colloid motors. The colloid motor takes a polyelectrolyte single-hole microcapsule loaded with photoacid as a core, and a capsule-like vesicle film is assembled on the surface of the polyelectrolyte single-hole microcapsule. The method comprises the following steps: extracting the thylakoid vesicles embedded with the biomolecular motor FlFo-ATP synthase by virtue of methods of homogenizing and homogenizing, gradient centrifugation and extrusion; 2, preparing a single-hole microcapsule by a heterogeneous nucleation, self-expansion and selective etching method; 3, carrying out layer-by-layer self-assembly by taking the single-hole microcapsule as a template to prepare a polyelectrolyte single-hole microcapsule; and 4, assembling the capsule-like vesicles on the surface of the polyelectrolyte single-hole microcapsule. By utilizing a unique single-hole channel structure, precise regulation and control on light-operated proton release and transmembrane transportation are realized, and the proton driving efficiency is remarkably improved, so that rotation of FlFo-ATP synthase is efficiently activated to synthesize ATP, a light response motion behavior is realized, and directional motion and energy metabolism regulation and control in a complex biological medium can be realized.
Owner:HARBIN INST OF TECH
An MBBR unit allowing homogeneous water distribution and high-performance BIO-media movement
The invention relates to an MBBR (Moving Bed Biofilm Reactor) unit (1) that reduces the amount of total nitrogen (TAN, NH3N), which yields fatal consequences for living organisms in living systems; requires no downtime for system maintenance; and maximizes the efficiency of the nitrification process by activating Nitrobacter and Nitrosomonas type bacteria. More specifically, the present invention relates to an MBBR unit (1) that allows for homogeneous water distribution and high-performance bio-media movement, which improves the performance values of the nitrification process vital for living systems, provides longevity, and increases efficiency while reducing water consumption.
Owner:MAT FILTRASYON TEKNOLOJILERI ANONIM SIRKETI
Bio-ink of photo-curable Matrigel matrigel, preparation method and application of bio-ink in volume bio-printing
PendingCN121944242ABreaking through the technical bottleneck of non-photocurable technologyFill application gapsAdditive manufacturing apparatusProsthesisMatrigelBiocompatibility
The invention belongs to the technical field of bio-printing, and particularly discloses bio-ink of light-curable Matrigel matrigel, a preparation method and application in volume bio-printing.The bio-ink is prepared by mixing hydrogel and Matrigel matrigel and then adding a photoinitiator, controllable curing can be achieved under irradiation of a light source, and the bio-ink has the advantages that the bio-ink can be applied to volume bio-printing; the problem that in the prior art, due to the fact that Matrigel matrigel lacks photosensitive groups, photo-crosslinking reaction cannot be carried out is solved, the bio-ink is further mixed with a biological medium, the composite bio-ink is obtained and perfectly compatible with the GLVBP technology, a printed and formed structure has high precision, high cell viability and good biocompatibility, and the composite bio-ink can be used for preparing the light-sensitive matrix gel. The method has a wide application prospect in the biomedical fields of organoid culture, tissue engineering and the like.
Owner:GUANGZHOU MEDICAL UNIV