29 results about "Simulated microgravity" patented technology

The invention provides a water floating 3D printing device and method for space additive manufacturing simulation verification, and relates to the field of space additive manufacturing. The water floating 3D printing device comprises a controller, a main mechanical arm, a 3D printing head, a microgravity printing environment simulation device, a micro mechanical arm and a sensor assembly. The microgravity printing environment simulation device comprises a water tank and a dynamic floating substrate unit. The dynamic floating substrate unit floats in the water tank to simulate a microgravity environment; the micro mechanical arm is used for regulating and controlling the nozzle position of the 3D printing head and ensuring that the nozzle is aligned with the floating substrate; and the main mechanical arm is used for moving the 3D printing head according to a preset printing path and assisting in regulating the position of the nozzle. According to the device, through a water floating method, the space microgravity environment can be effectively simulated, the micro mechanical arm and the mechanical arm of the main machine work cooperatively, and accurate and rapid printing can be achieved. According to the invention, a space-imitated environment is provided for fused deposition modeling printing, and the experiment of additive manufacturing of the space-imitated environment can be carried out on the ground.

The application provides a device and method for simulating microgravity fluid on the ground by using motion method, and belongs to the field of ground microgravity simulation. The application comprises a microcomputer control system, a fluid carrier U-shaped pipe, a gas source power equipment and a sensor detection system. The pipe opening of the U-shaped pipe is upward and is fixed on the ground near by a support. The two ends of the pneumatic pipeline in the gas source power equipment are connected with the two vertical sections of the U-shaped pipe through rubber hoses. The sensor detection system is used for detecting and collecting the motion parameters of the liquid fluid in the U-shaped pipe. The sensor detection system is connected with the microcomputer control system, and the microcomputer control system is used for controlling the gas source power equipment. The application adopts the motion method to make the liquid fluid move in the U-shaped pipe in a set rule. The acceleration of the liquid fluid in the motion process is consistent with the gravity field by the microcomputer control system, so as to eliminate the gravity influence between the micro elements of the liquid fluid and achieve the weightlessness.

The application discloses a laser coaxial fuse additive equipment and method for simulating a microgravity environment, which comprises a laser coaxial fuse additive equipment body, a negative pressure suction method device is installed on a laser coaxial fuse wire feeding nozzle part, a plurality of liquid nitrogen flow pipes are arranged on the top outer side of the negative pressure suction method device and are externally connected with cooling substances through the liquid nitrogen flow pipes, airflow pipes are installed on both sides of the negative pressure suction method device, and cooling housings are fixedly connected with the top of the airflow pipes through the airflow pipes, the whole process creates an annular negative pressure suction field in the vertical direction according to the Bernoulli principle, and the gravity is balanced in real time, so that the laser fuse additive under the microgravity environment can be simulated for a long time, continuously, at low cost and truly, the liquid nitrogen cooling and protective airflow device are integrated, the influence of thermal expansion caused by high temperature generated by laser heating on airflow disturbance and deformation of the negative pressure suction method device can be offset, and meanwhile, the side-blowing protective gas device can be replaced, so that oxidation in the additive printing process is prevented.

The application discloses a microgravity simulation device and method, and relates to the technical field of ground microgravity simulation, and aims to solve the problems of high cost and short experiment duration in the prior art. The microgravity simulation device comprises a rotating driving mechanism, at least one floater and at least one container for containing a liquid medium. The rotating driving mechanism has at least one power output shaft, each floater is arranged on a corresponding power output shaft, the floater floats on the liquid medium, the center of mass of the floater is located above the liquid medium, and the distance between the geometric center of the floater and the center of mass of the floater is greater than 0. The method of the microgravity simulation device is used for simulating microgravity. The microgravity simulation device and method provided by the application are used in microgravity simulation.

The invention discloses a 3D printing cabin for simulating an extraterrestrial environment, and belongs to the field of 3D printing, and the 3D printing cabin comprises a control cabinet, and a main vacuum cabin, a printing execution system, a vacuumizing system, a control cabinet, a monitoring system, an environment simulation system and a self-cleaning system which are electrically connected with the control cabinet. The full-closed-loop ground verification system integrating multi-field coupling environment simulation, high-precision in-situ additive manufacturing, whole-process monitoring and equipment self-maintenance is provided. The environment simulation system can synchronously reproduce space extreme high-low temperature alternating and ultraviolet radiation environment through the cooperation of an infrared heating array and an ultraviolet radiation array; the printing execution system is integrated with a sealed filler cabin and a quick-release sealing mechanism, and supports high-precision printing under the simulated microgravity mechanics condition; the self-cleaning system achieves automatic cleaning in the experiment rear cabin, and it is ensured that no cross contamination exists between experiments.

The invention provides a ground test device for simulating a detection instrument under combined conditions of microgravity, high and low temperature and vacuum. The ground test device comprises high and low temperature vacuum environment test equipment; the detector inclination angle simulation assembly is of a plate-shaped structure and simulates the bottom of the detector; the slow release device electric simulation assembly is fixed in the middle of the detector inclination angle simulation assembly; one end of the electric simulation assembly slow release rope is fixedly connected with the slow release device electric simulation assembly; the detection instrument is hung below the electric simulation assembly of the slow release device through an electric simulation assembly slow release rope; one end of the umbilical cable is fixedly connected with the detection instrument, and the other end is fixedly connected with the detector inclination angle simulation assembly; the detector inclination angle adjusting assembly adjusts the included angle between the detector inclination angle simulation assembly and the horizontal plane; and the planet surface gradient simulation assembly is used for simulating a planet surface environment. The device has the advantages that under the condition that the temperature and the vacuum environment of the device are not affected, adjustment is carried out among multiple test modes and multiple test device states.

The utility model relates to the technical field of anode material processing equipment, and discloses microgravity granulation equipment for anode material synthesis, which comprises a tower body, and a channel falling along the gravity direction is arranged in the tower body; the atomizing nozzle is arranged at the top of the tower body; the heat radiation heating device is arranged on the side wall of the tower body; and the vacuum system is connected with the tower body and is used for maintaining the vacuum degree in the tower body. According to the equipment, a high-vacuum-degree environment is constructed, a specific falling stroke is combined, and the surface tension spontaneous shrinkage effect of liquid drops in a simulated microgravity state is utilized, so that positive electrode material precursor particles with high sphericity, high stacking density and a compact internal structure can be prepared.

Disclosed herein are systems and methods for testing effects of simulated microgravity on muscle structures. The system includes a clinostat and an adapter that is receivable into the clinostat. The adapter includes a housing that defines at least one receptacle. The system further includes an assembly having a substrate and a plurality of fibrils deposited on the substrate. The plurality of fibrils comprise collagen and extend along an axis. The assembly is receivable into a first receptacle of the at least one receptacle. The plurality of fibrils can have myoblasts thereon. Operation of the clinostat simulates microgravity. Test substances can screened using the muscle structures to determine effects on myogenesis.

This invention provides a ground-based experimental method for the rotational unlocking and separation of satellites between layers. The method includes placing satellites on a tooling and placing an air cushion at the bottom of the tooling, so that the satellites and tooling are suspended, simulating a microgravity scenario. An unlocking device is used to lock and unlock the satellite layers. A nozzle structure is placed on either side of the tooling bottom to enable rotation between satellites in the same layer. Simultaneously, a cushioning rubber releases the compression force to separate the two satellites, ensuring collision-free rotation. This experimental method facilitates ground-based simulation experiments for the unlocking and separation of satellites between layers, and the simulation results are accurate and reliable, providing a reference for solving the problem of stacked satellite separation.

The present invention relates to: a cell culture platform in which cell culture is enabled in a state capable of simulating microgravity by mixing a density control solution into a cell culture medium to adjust density of the cell culture medium to a density range of cells; and a cell culture comprising cells prepared therefrom. Since the cell culture platform of the present invention can overcome limitations of existing microgravity platforms simulated on the ground, including excessive cost and side effects caused by application of additional external force, the cell culture platform is expected to be usefully applicable in the aspects of regenerative medicine, immunology, and pharmacology as well as in those of space biology and space medicine.

Microgravity simulation systems and methods of simulating microgravity are disclosed. This disclosure relates to a microgravity simulation system having multiple platforms, where each platform may include an outer rotating element, an inner rotating element, a sample station coupled to the inner rotating element. The microgravity simulation system may include where multiple rotating elements of each of the plurality of platforms are rotated either independently or synchronously. Furthermore, each platform of the microgravity simulation system may include a lighting element, or in particular a multi-spectral lighting element.

The application provides a test device suitable for two-dimensional impact test of particle flow under simulated microgravity conditions, which comprises a test box, a balancing system, a power and control system and a measuring system, wherein the test box comprises a box body and a test table, the test table is supported in the box body; the balancing system is used for adjusting the horizontal degree of the test box and the test table and the gravity acceleration value of the plane where the test table is located; the power and control system is used for providing power and driving control for the equipment in the device; and the measuring system is used for monitoring the whole process from the initial flow to the impact and to the final stability. The application can obtain the movement law of the particle flow in the microgravity environment under a relatively easy-to-control and low-cost environment, lays a certain test foundation for three-dimensional microgravity tests such as drop tower test and space station test, thereby promotes the understanding of engineering problems and geological problems under the extraterrestrial microgravity environment, and has important engineering application prospect and scientific value.

The present disclosure provides methods for improving the differentiation potency using simulated microgravity. The improvement in differentiation is relative to stem cells that are cultured at 1 g (i.e., at Earth's gravity). In various examples, the improvement is at least 2x better than cultures relative to stem cells that are cultured at 1 g. Also disclosed are methods of differentiating cells cultured by the methods described herein.

This utility model discloses a backpack-type space-assisted training robotic arm, specifically relating to the field of robotic arm technology. It includes a carrying strap, an upper robotic arm, a front robotic arm body, and a hand end effector device. The carrying strap is connected to the upper robotic arm, and the upper robotic arm is connected to the front robotic arm body. The front robotic arm body also preferably has a hand end effector device at its front end. These four parts are interconnected via various telescopic shafts, and wiring is provided according to the connections of each part. This utility model employs an optimized backpack-type space-assisted training robotic arm to simulate the motion states of different masses and the interaction forces between the astronaut and the spacecraft in a simulated space operation environment on the ground. This achieves virtual operation training and a sense of presence for astronauts in a simulated microgravity environment, helping them learn how to operate objects of different masses and avoiding collisions due to operational errors.

The application discloses a kind of magnetic compensation method simulation microgravity heat pipe comprehensive testing device and testing method, testing device includes each other associated magnetic field generating system, magnetic field calibration system, force measurement system, heat pipe performance testing device and visual observation system;Magnetic field generating system includes rectangular coupling coil, cooling circulation system, power control cabinet;Magnetic field calibration system includes high-precision hall probe, three-dimensional stepping platform, control acquisition system;Force measurement system includes support bracket and force sensor;Heat pipe performance testing device includes heat pipe to be measured, electric heating system, heat insulation device and data acquisition system;Testing method includes electric control magnetic field generation stage, field parameter determination stage, heat pipe start-up operation and acquisition analysis stage in order of precedence.This application can provide large size microgravity environment suitable for heat pipe performance comprehensive test, can carry out reliability verification of space heat pipe for space reactor on ground, meet the demand of heat pipe deep research and development.

The invention discloses a laser coaxial fuse wire additive material device and method for simulating a microgravity environment, and the device comprises a laser coaxial fuse wire additive material device body, and a laser coaxial fuse wire feeding nozzle part is provided with a negative pressure suction method device. A plurality of liquid nitrogen circulation pipes are arranged on the outer side of the top of the negative pressure suction method device and externally connected with a cooling substance through the liquid nitrogen circulation pipes, airflow pipes are installed on the two sides of the negative pressure suction method device, a cooling shell is fixedly connected to the top of the negative pressure suction method device through the airflow pipes, and an annular negative pressure suction field is built in the vertical direction according to the Bernoulli principle in the whole process; according to the device, the gravity is balanced in real time, the laser fuse wire additive material in the microgravity environment can be simulated continuously and truly for a long time at low cost, the liquid nitrogen cooling and air flow protection device is integrated, the influence of thermal expansion caused by high temperature generated by laser heating on air flow disturbance and negative pressure suction method device deformation can be counteracted, and the laser fuse wire additive material is obtained. And meanwhile, a side-blowing protective gas device can be replaced, and oxidation in the additive printing process is prevented.

The application discloses a method for improving electricity generation, electrochemically active microorganism abundance and biomass of a microbial fuel cell under simulated microgravity. The microbial fuel cell is a novel electrochemical device for generating electricity by using electrochemically active microorganisms, and has a good application prospect in the space field. However, the feasibility of the microbial fuel cell applied to the space field has not been reported. A key scientific problem is how the unique microgravity condition in the space field affects the microbial fuel cell and the electrochemically active microorganism, which is not clear. In order to solve the problem, the application discloses a method for improving electricity generation, electrochemically active microorganism abundance and biomass of a microbial fuel cell under simulated microgravity. Under the simulated microgravity condition, the total biomass of the microbial fuel cell is increased, and the abundance of the electrochemically active microorganism is improved, so that the biomass of the electrochemically active microorganism is increased, and the electricity generation of the microbial fuel cell is increased. The application provides a theoretical basis for the feasibility of the microbial fuel cell applied to the space field.

The invention discloses an air floating type gravity unloading platform ground experiment system and method for a satellite prototype, and the system comprises an air floating motion platform which is used for simulating a microgravity environment; at least two modularized spacecrafts, each modularized spacecraft is carried on the corresponding air flotation motion platform, and a controlled connection release mechanism is arranged between the modularized spacecrafts and is used for realizing physical connection and separation between the modularized spacecrafts in the experiment process; the cooperative control and evaluation system is used for calculating a multi-dimensional index for quantitatively evaluating the task efficiency based on the acquired pose and action data in the task execution process or after the task execution is finished; according to the invention, the space environment is simulated by building each subsystem, the building of the modular satellite ground semi-physical simulation verification environment is realized, and the application research of a modular satellite prototype can be effectively supported.

Embodiments of the present disclosure disclose a mixed reality-based simulation of microgravity environment hand-object grasping method and device. A specific embodiment of the method includes: detecting the posture information of the hand in real time to obtain the hand posture information; detecting the collision between the hand and the object in real time to obtain the hand-object collision condition; and performing a hand-object interaction action according to the hand posture information and the hand-object collision condition. This embodiment provides a highly efficient and practical ground grasping simulation training tool for astronauts, enabling them to better prepare for space missions and ensuring that they can safely and accurately perform grasping operations in a real space environment.

This invention discloses a ground-based experimental system and method for an air-floating gravity unloading platform for satellite prototypes, comprising: an air-floating motion platform for simulating a microgravity environment; at least two modular spacecraft, each of which is mounted on a corresponding air-floating motion platform, and the modular spacecraft are provided with a controllable connection and release mechanism for realizing physical connection and separation between the modular spacecraft during the experiment; and a collaborative control and evaluation system for calculating multi-dimensional indicators for quantitatively evaluating mission effectiveness based on collected pose and motion data during or after mission execution. This invention, by building various subsystems to simulate the space environment, realizes the construction of a ground-based semi-physical simulation verification environment for modular satellites, which can effectively support the application research of modular satellite prototypes.

The present invention relates to a biodegradable polymer, a preparation method and a sustained-release microneedle patch, and belongs to the field of biomaterial technology. The polymer is polyethylene glycol-polysulfadimethoxine carbonate carbamate, and the polymer has good biocompatibility and biosafety. Through a series of simple synthesis methods, including acrylic acid reaction, Michael addition reaction, ring-opening reaction, and addition polymerization reaction, a PEG-PSCU polymer is finally obtained, which can be used to prepare a new sustained-release microneedle. Compared with traditional biodegradable microneedles, this new microneedle can not only efficiently load protein vaccines, but also further prolong the release time of these vaccines in different environments, including normal ground environment and simulated microgravity environment, and further enhance the mechanical strength of the microneedle itself.

The present invention relates to: a cell culture platform in which cell culture is enabled in a state capable of simulating microgravity by mixing a density control solution into a cell culture medium to adjust density of the cell culture medium to a density range of cells; and a cell culture comprising cells prepared therefrom. Since the cell culture platform of the present invention can overcome limitations of existing microgravity platforms simulated on the ground, including excessive cost and side effects caused by application of additional external force, the cell culture platform is expected to be usefully applicable in the aspects of regenerative medicine, immunology, and pharmacology as well as in those of space biology and space medicine.

The invention belongs to the technical field of cell biology, and particularly relates to an anti-aging mesenchymal stromal cell as well as a construction method and application thereof. The construction method of the anti-aging mesenchymal stromal cells comprises the following steps: S1, culturing in vitro and carrying out passage on the mesenchymal stromal cells to P5 to P10 generations; s2, placing the mesenchymal stromal cells in a microgravity environment for rotary culture; and S3, digesting the cultured cells to obtain the anti-aging mesenchymal stromal cells. Compared with the prior art of simulating microgravity to explore phenotypes such as morphology, proliferation, immunity and the like of the mesenchymal stromal cells, a new breakthrough is made, and a new strategy and thought are provided for delaying stromal cell senescence, researching mechanisms of space weightlessness related diseases and increasing clinical application of stromal cells.

The application provides a device for simulating a microgravity environment by using ultrasonic waves and a test method thereof, and belongs to the field of microgravity environment simulation devices. The device solves the problem that in the existing acoustic levitation device, ultrasonic transducers are distributed on the bottom, and untrapped particles fall onto the surface of the ultrasonic transducers to cause pollution. The reflecting cover is fixedly arranged above the support; the ultrasonic transducer array is arranged below the reflecting cover, and a suspension space is formed between the ultrasonic transducer array and the reflecting cover; an avoiding space is arranged at the middle position of the ultrasonic transducer array, and the avoiding space is in communication with the suspension space; a single-chip microcomputer, a power amplifier, a matching circuit and the ultrasonic transducer array are sequentially electrically connected; and the particle input pipeline is fixedly arranged on the support, and the outlet of the particle input pipeline is in communication with the suspension space. Untrapped particles can leave the suspension space through the avoiding space, and the ultrasonic transducers are not polluted.

The invention discloses a 3D biological membrane culture device for simulating microgravity and variable gravity effects. The 3D biological membrane culture device comprises a double-shaft rotating mechanism, an oxygen-permeable annular culture module and a biological membrane culture plate, wherein the oxygen-permeable annular culture module is integrally processed and formed and is positioned on the biological membrane culture plate; and the biological membrane culture plate is mounted on the double-shaft rotary module. According to the 3D biological membrane culture device for simulating the microgravity and variable gravity effects, the integrated oxygen-permeable annular culture module is designed, simulation culture of a 3D biological membrane of a space-like pipeline structure can be carried out in the device, and the biological membrane forming process under different space environments (microgravity and variable gravity) is simulated.

This invention discloses a device and method for free exploration in different spatial dimensions based on rich information, including: a one-dimensional ring-shaped unidirectional free exploration device, a two-dimensional open field free exploration device, and a three-dimensional behavior box free exploration device. Using the free exploration devices in different spatial dimensions can not only explore the spatial information representation of rat hippocampal position cells in different spatial dimensions, but also explore whether there is a certain time-varying law in the dynamic changes of rat spatial information encoding ability under long-term simulated microgravity. This creates conditions for further exploring the internal neural mechanisms of the influence of simulated microgravity factors on spatial memory and other aspects.

A cultivation method for simulated microgravity-induced reprogramming of primary cancer cells and related culture media and reagents are in the field of biotechnology. A multi-directional G-force generator is used to simulate a 10−3 g microgravity environment, inducing reprogramming of cancer / cancer-adjacent tissue cells derived from patients, maintaining stemness of primary cell populations, and achieving rapid, long-term, high-fidelity cultivation of tissue cells from patients. Using this cultivation method, 106 cells can be obtained within 7 days from a 1 mm3 tissue block acquired during surgery for drug screening. Specially formulated culture media, washing solutions, and digestion solutions are also provided, effectively solving problems of contamination susceptibility and difficult digestion of clinical samples. The established cancer cell models maintain highly similar genetic characteristics to the original tissue and can reflect differences in drug sensitivity between different patients, providing a powerful tool for precision cancer treatment.

A cultivation method for simulated microgravity-induced reprogramming of primary cancer cells and related culture media and reagents are in the field of biotechnology. A multi-directional G-force generator is used to simulate a 10−3 g microgravity environment, inducing reprogramming of cancer / cancer-adjacent tissue cells derived from patients, maintaining stemness of primary cell populations, and achieving rapid, long-term, high-fidelity cultivation of tissue cells from patients. Using this cultivation method, 106 cells can be obtained within 7 days from a 1 mm3 tissue block acquired during surgery for drug screening. Specially formulated culture media, washing solutions, and digestion solutions are also provided, effectively solving problems of contamination susceptibility and difficult digestion of clinical samples. The established cancer cell models maintain highly similar genetic characteristics to the original tissue and can reflect differences in drug sensitivity between different patients, providing a powerful tool for precision cancer treatment.

The application provides a device for simulating the ground test of a detection instrument under the combined conditions of microgravity, high and low temperature and vacuum, comprising: a high and low temperature vacuum environment test equipment; a plate-shaped detection device tilt angle simulation assembly simulating the bottom of the detection device; a slow-release device electric simulation assembly fixed in the middle of the detection device tilt angle simulation assembly; an electric simulation assembly slow-release rope fixedly connected to one end of the slow-release device electric simulation assembly; a detection instrument hung below the slow-release device electric simulation assembly by the electric simulation assembly slow-release rope; an umbilical cable fixedly connected to one end of the detection instrument and the other end of the detection instrument; a detection device tilt angle adjustment assembly adjusting the included angle between the detection device tilt angle simulation assembly and the horizontal plane; and a planet surface inclination simulation assembly simulating the surface environment of a planet. The application has the advantages that the temperature and vacuum environment of the device are not affected, and the state of various test modes and various test devices can be adjusted.