47 results about "Skull surface" patented technology

The invention discloses a three-dimensional craniofacial reconstruction method based on the overall facial structure shape data of Chinese people, comprising the following steps of: (1) acquiring a thickness distribution model of a facial soft tissue based on the statistic analysis of a large amount of human head CT (Computed Tomography) data; (2) unfolding the soft tissue layer and the skull surface layer of a human head through a cylinder, and projecting the soft tissue layer and the skull surface layer to a two-dimensional flat surface, representing the soft tissue shape and the skull shape by using a two-dimensional depth map, and training a radial basis function network to realize the change between the skull to be reconstructed and the common soft tissue thickness distribution form; (3) constructing a shape subspace of local organs of the reconstructed face based on the craniofacial facial structure shape classification of human species, and learning the mapping between the craniofacial local shape and the local shape of the reconstructed face; (4) correcting the reconstructed face model by combining the integral soft tissue distribution and the local characteristic shape deformation, i.e. completing three-dimensional craniofacial reconstruction and correctness of the input skull by adding the two-dimensional depth maps of the soft tissue shape and the shape of the skull to be reconstructed; and (5) synthesizing a complete texture graph of the face through facial texture mapping by using orthogonal pictures, and rendering the skin color and the hair style of the reconstructed human picture to enhance the reality sense of the human picture. By applying the method, the problems of missing reconstruction details and lack of individual characteristics are solved, the manufacturing cost of other anthropology researches and reconstruction technologies is saved, and the working efficiency is improved. The invention has high automation degree and simple operation.

The present invention relates to an “structure improvement of the pillow”, which comprises a central main pillow and two lateral sub-pillows, wherein, said central main pillow is trapezoid in dimension with height of pillow top and central length such that the height of pillow top approximately equals the distance between the outer hind skull surface to the outer surface of the normal arched cervical vertebra when people lies on one's back while the height of central length approximately equals the distance between the outer side surface of two ears of human head with slight clearance for tolerance; said lateral sub-pillow is trapezoid in dimension with height of pillow top and the height of pillow top approximately equals the distance between the outer side skull surface to the outer side surface of the shoulder when people lies on one's side; The characterized is that a pair of symmetrical skew-angled arrangement for said central main pillow and each of said two lateral sub-pillows is formed in disposal so that the user head can be exactly placed on and closely supported by one of the two lateral sub-pillows completely when the user lies on one's side sleeping posture; Besides, a sunken dent space is created on the central top of the lateral sub-pillow so that the user ear will be not pressed without uncomfortable feeling.

A system and method are provided for using a computer system to assist in planning a trajectory (960A, 960B) for a surgical insertion into a skull. The method comprises providing the computer system with a three-dimensional representation of the skull and of critical objects located within the skull, wherein the critical objects comprise anatomical features to be avoided during the surgical insertion. The method further comprises providing the computer system with a target location (770, 970) for the insertion within the skull. The method further comprises generating by the computer system a first set comprising a plurality of entry points, each entry point (760) representing a surface location on the skull, and each entry point (760) being associated (2D) with a trajectory (960A, 960B) from the entry point (760) to the target location (770, 970). The method further comprises discarding by the computer system entry points from the first set to form a second, reduced set comprising a plurality of entry points, wherein an entry point (760) is discarded from the first set of entry points if the entry point (760) has an entry angle which fails a condition for being substantially perpendicular to the skull surface. For each entry point (760) in the second set, the computer system assess the entry point (760) against a set of one or more criteria, wherein the set of one or more criteria includes a risk factor based on the separation between the critical objects and the trajectory (960A, 960B) which is associated with said entry point (760)). This risk factor may be calculated by integrating f(x) along the trajectory (960A, 960B) associated (2D) with the entry point (760), where x represents distance along the trajectory (960A, 960B) to a sample point, and f(x) is a function based on distance from the sample point at distance x to a critical object which is nearest to said sample point.

A system and method are provided for using a computer system to assist in planning a trajectory (960A, 960B) for a surgical insertion into a skull. The method comprises providing the computer system with a three-dimensional representation of the skull and of critical objects located within the skull, wherein the critical objects comprise anatomical features to be avoided during the surgical insertion. The method further comprises providing the computer system with a target location (770, 970) for the insertion within the skull. The method further comprises generating by the computer system a first set comprising a plurality of entry points, each entry point (760) representing a surface location on the skull, and each entry point (760) being associated (2D) with a trajectory (960A, 960B) from the entry point (760) to the target location (770, 970). The method further comprises discarding by the computer system entry points from the first set to form a second, reduced set comprising a plurality of entry points, wherein an entry point (760) is discarded from the first set of entry points if the entry point (760) has an entry angle which fails a condition for being substantially perpendicular to the skull surface. For each entry point (760) in the second set, the computer system assess the entry point (760) against a set of one or more criteria, wherein the set of one or more criteria includes a risk factor based on the separation between the critical objects and the trajectory (960A, 960B) which is associated with said entry point (760)). This risk factor may be calculated by integrating f(x) along the trajectory (960A, 960B) associated (2D) with the entry point (760), where x represents distance along the trajectory (960A, 960B) to a sample point, and f(x) is a function based on distance from the sample point at distance x to a critical object which is nearest to said sample point.

The invention is particularly suitable to restitution of complex deformity of skull surface. Based on computer image processing and CAD, emulation of 3D segmentation and reconstruction is carried out for structure of skull surface matched to real body. Qualitative even accurate quantitative analyses are carried out for shape and structure of injured skull (including eye socket). The invention discloses layered osteotomy method of splitting off skull socket and surface along natural curvature in middle. The method includes following steps: in operation, fixing moved position promptly; embedding bone tractor to move position gradually; reconstructing skull surface such as inverted valve with vessel pedicle behind the ear. The invention reconstructs fine figure of face to recover normal function.

The invention discloses a temporomandibular joint deformity correction system and a method for making a personalized deformity correction device. The method comprises 1, analyzing an occlusal function through an occlusion analysis system to determine an occlusion position, 2, preparing original upper and lower jaw models according to the occlusion analysis system and re-positioning an occlusion plate through patient wearing with the original upper and lower jaw models, 3, carrying out re-examination on the patient each month, 4, after re-examination, determining whether the occlusion position is correct and carrying out deformity correction, 5, stabilizing the occlusion position and carrying out a tooth arrangement test, and 6, producing the personalized deformity correction device according to the tooth arrangement model after the tooth arrangement test. Compared with the prior art, the system realizes personalized tooth arrangement through combination of an adjustable frame, function analysis and projective measurement analysis according to the patient's skull surface type, utilizes a covering material to precisely control the position of the occlusion position, prevents occlusion position change, evaluates the tooth movement amount in a visual state through 3D data scanning before and after tooth arrangement and provides good deformity correction treatment guidance for later treatment.

The invention discloses a skull side surface image analysis method based on a neural network and a random forest, and a system. After imaging equipment (commonly oral and maxillofacial tomography equipment, CBCT in short) finishes patient skull side surface exposure and picture combination, an imaging result is input into a skull side surface dissecting characteristic marking module. Through a series of computer automatic identification and marking processes, marking operation of important dissecting structures on the image is finished, and high-precision positions of characteristic points are output. Afterwards a skull side surface report generating module receives the position of each dissecting characteristic point after artificial verification and adjustment by the skull side surface dissecting characteristic marking module and finishes skull surface medical analysis, wherein a final skull side surface analysis report is used as a subsequent diagnosis basis of the doctor. The method and the system have advantages of settling a problem of performing quick automatic analysis on the skull side surface image, greatly reducing physical labor of a doctor in a skull side surface imaging analysis process, shortening a diagnosis period, improving system predicting stability and preventing abnormal results.

The invention discloses a carp electrode transforation implantation brain stereo positioning method, which belongs to the technical field of brain stereo positioning. The invention mainly solves the problem of accurate positioning in electrode implantation into brain without craniotomy. The method comprises the following steps: drawing a straight line centrally from the carp mouth to the intersection point between the head and the first scale of the trunk, and drawing a straight line parallel to the central line based on the upper edges of two orbits respectively; drawing a connection line along the front edges of the two orbits; drawing a connection line along the rear edges of the two orbits; drawing a connection line between the joint moving joint points of the operculum bones on the two sides and the orbit bones; and drawing a line through the joint between the head and the first scale of the trunk and vertical to the central line. The skull surface is divided into 6 areas by the 7 lines, each area representing a coordinate system. The mouth, dorsal fin and operculum on the two sides clamp 4 points for fixing; in the positioning of a brain stereotaxic instrument, an electrode is implanted into the brain along a skull hole, and magnetic resonance imaging equipment navigates and corrects deviation so as to realize three-dimensional accurate positioning without craniotomy. The invention is applicable to the collection of brain wave of aquatic animals or control on biological behavior by conduction of electrical signals.

The invention discloses a carp brain electrode implantation method by means of magnetic resonance positioning and navigation. Taking the first fish scale (the junction of the head and the trunk) as the origin, reference scratches are made on the surface of the skull based on the characteristics of the carp skull to establish Space coordinate system; with the help of the T2WI fast spin echo scanning sequence of the magnetic resonance equipment, the brain is scanned and imaged, the two-dimensional coordinates of the electrode stimulation site are converted into three-dimensional space coordinates, and the spatial coordinates of the brain stimulation electrode implantation site are determined The coordinate value of the system; according to the coordinate value, the brain stimulation electrode is implanted for positioning and navigation. The invention can not only locate and navigate for the implantation of the carp aquatic animal robot brain stimulation electrodes, but also provide new positioning and navigation means for the implantation of various animal robot brain stimulation electrodes.

A fixation device including a base structure such as a faceplate having an inferior surface capable of contacting a surface of a skull of a patient, having a superior surface, and defining at least two securement features. Each securement feature can be engaged by a cranial fastener to attach the faceplate to the skull. The device further includes a fixation structure such as an alignment plate or a flexible fixation member carried by the base structure and positionable at least one of (i) over an opening in the skull and (ii) within an opening in the skull. At least one surface of the fixation structure defines at least one channel in which an intracranial device is capable of being placed, and further defines at least one fixation feature to enable the intracranial device to be secured to the fixation device.

The invention discloses a magnetic adsorption type decontamination robot comprising a triangular vehicle body shell, an electromagnet sucking disc and plate-shaped lithium battery connecting component, a lithium battery and signal receiver module connecting component and decontamination brush discs. A vehicle body frame is fixedly mounted on the bottom of the triangular vehicle body shell, and driving motors and the lithium battery and signal receiver module connecting component are arranged in a spatial area formed by the portion above the triangular vehicle body shell and the triangular vehicle body shell. The other end of a connecting rod is hinged with a hydraulic rod, and a rotatable camera is mounted on the connecting side surfaces between the support rod and the hydraulic rod. According to the magnetic adsorption type decontamination robot, during operation, electromagnet sucking discs at the bottom of the vehicle body are energized; the decontamination robot is adsorbed on thesurface of the steel hull; and the driving motors work to drive crawler belts, so that the decontamination robot starts to advance. In addition, rotating motors drive the decontamination brushing discs to rotate so as to remove the attachments on the skull surface.

The present invention discloses a beam assisted positioning method for craniotomy and a positioning system of the beam assisted positioning method for craniotomy. The system comprises a preoperative planning system, a beam positioning device and a binocular vision camera with a three-dimensional coordinate system registration function; and the positioning method comprises: 1) based on CT images, conducting three-dimensional view reconstruction of skull surface and scalp of patients; 2) marking a head patch of the patients in three-dimensional views and planning a skull windowing path and a scalp incision path; 3) using the binocular vision camera to detect heads the patients the patch at a beam emitting device to obtain a transformation relationship between a three-dimensional view coordinate system and a beam coordinate system through spatial registration, so as to accurately drive beam emitted by the beam emitting device to be consistent with the planned surgical path; and 4) finallyusing a beam movement method to confirm the scalp incision path and skull windowing path by doctors. The positioning method and system avoid excessive dependence on human experience, reduce preoperative preparation time, relieve medical staff fatigue, and improve safety and rationality of the craniotomy.

The invention discloses a manufacturing method of an individualized brain space 125I seed implantation auxiliary localizer, comprising the following steps: S1, obtaining head CT scanning data, determining an operation surface and three auxiliary localization surfaces on the brain CT image data; S2, determining the operation surface and three auxiliary localization surfaces on the head CT image data; S2, determining the coverage area of the positioner on the operation surface and the three auxiliary positioning surfaces; S3, spatial repositioning of the positioner; S4, designing the structure of each surface of the positioner; S5, using 3D printer, the designed brain tumor 125I seeds are implanted into the positioner to print the integrally formed skull surface component. The invention utilizes the individualized brain space stereotaxic positioning technology, CT image data, 3D printing technology and 125I seed TPS treatment planning system are used to make 3D printing brain tumor 125Iseed implantation localizer, which can assist the planed implantation of 125I seed into malignant intracranial brain tumor, minimally invasive diagnosis and interventional treatment of brain tumor.

The invention discloses a skull surface fixing cap, wherein the skull surface fixing cap comprises a brimless round cap part, a jaw fastening strap and a convex part which extends to eyebrows, wherein two sides of the brimless round cap part are connected to two ends of the jaw fastening strap; the convex part is integrally connected to one side of the outer edge of the brimless round cap part, and the convex part is located between two ends of the jaw fastening strap; a first convex device is arranged at the convex part and the first convex device is aligned with the eyebrows of a human body; and a second convex part is arranged at the lower side of the jaw fastening strap and the second convex device is aligned to chin of the human body or the front side of a trachea. According to the skull surface fixing cap provided by the invention, a steel ball serves as a reference substance, and the steel ball, which is sutured in the fixing cap, is kept fixedly; and in addition, the fixing cap is recyclable.

The invention relates to the field of biology materials, in particular to a method for treating an externally-autoplastic autogenous skull sheet, which includes: 1 freezing fresh skull flap for 24 hours at temperature of -10 DEG C, rewarming for 48 hours in natural environment (about 20 DEG C) so as to break integrity of cells and lead the cells to be self-dissolved fully; 2 removing soft tissue on the surface of skull manually; 3 drilling holes on the skull in mesh mode and leading areas among holes to be 1cm*1cm; 4 soaking distilled water and trypsin for 48 hours at the temperature of 37 DEG C, changing the distilled water every 24 hours so as to fully precipitine an autogenous solution; and 5 soaking for 72 hours in medical hydrogen dioxide, changing the hydrogen dioxide every 24 hours to fully remove proteins in diploe; and soaking for 12 hours in the distilled water and then draining when no adverse reactions including infection, effusion and the like appear. Aiming at the problem that ankle joints are movable so that needle heads on the foot portion can move easily, the method combines special structure of the foot portion for fixing the foot portion so as to prevent liquid medicine from permeating into subcutaneous tissues.

The invention discloses a cryopreservation method of an autologous skull. The method is used for solving the problem that autologous skulls are polluted easily by a preservation medium in the prior art and can be used to improve bone growth activity. Preservation is carried out by sequentially adopting the following steps: performing pretreatment, performing washing, performing pre-freezing, preparing a gel, performing radiation sterilization, performing freezing storage and performing post-treatment. A preparation process of the gel is combined with preservation of an autologous skull, then the gel with growth activity is embedded in gaps on the surface of the skull, and growth of bones is promoted after replantation. According to the invention, a preparation process of polyvinyl alcohol(PVA) hydrogel carrying nano-hydroxyapatite (n-HA) is combined with preservation of the autologous bone, the PVA hydrogel in a liquid state is in full contact with bone tissues, and the PVA hydrogel forms a gel when the skull is taken out, so that adhesive force of the gel on bones is improved, exogenous pollution is avoided, and bone growth after replantation can be promoted.

The invention provides a bendable pulse generator and an implantable nerve electrical stimulation system. The bendable pulse generator comprises a main body part and a top cover part, a first part component is installed on the main body part, a second part component is installed on the top cover part, and the second part component and the first part part component can be connected through a circuit; and a soft coating layer partially or completely coats the main body part and the top cover part, and a soft connecting part is formed between the main body part and the top cover part. The invention discloses the bendable pulse generator, the main body part and the top cover part can be relatively bent for a certain angle through the flexible connecting part; when the bendable pulse generatoris implanted into the head of a human body, only the main body part needs to be installed in the skull groove, and the top cover part is bent by a certain angle relative to the main body part and thenattached to the surface of the skull, so that the formed skull groove is small and shallow, the operation difficulty can be reduced, the postoperative effect is good, and the pain of a patient is small.

The invention concerns an arrangement and a procedure for the spatial directed capturing of the electro encephalogram from selected brain areas with electrodes that are attached on the skull surface of an examined person. According to the invention, several electrodes are arranged on the skull surface in such a way, that a part of the electrodes capture the electrical activity generated from the targeted brain area. Another part of the electrodes captures the electrical activity from the targeted area and the disturbing electrical activity generated by the adjacent areas. This is considerably reduced with the help of an electronic circuit and methods of signal processing.

The invention provides a craniotomy device and method for brain surgery, comprising: a positioning sleeve, the positioning sleeve is provided with an adjusting hoop that is threadedly matched with the adjusting hoop, and a There is a scale, and a sliding sleeve with a clearance fit is provided outside the adjusting hoop, and a righting limit sleeve that is rotationally connected is provided at the lower part of the sliding sleeve, and a drill pipe is arranged inside the righting limit sleeve, and a universal leveling joint is provided at the lower end of the drill pipe in turn And the casing drill, the casing drill is provided with a suction seat. In the present invention, the contact surface between the strip-shaped annular teeth and the skull is small, and the fit with the skull surface is good, so that all the annular teeth are in uniform contact with the skull surface, and the vibration force is extremely small during drilling, which can smoothly The skull hole is drilled through, and the phenomenon of drill sticking will not occur, and the drilling process is relatively simple and smooth; at the same time, the righting limit sleeve drill will not invade the meninges, the difficulty of drilling on the skull is extremely low, and the drilling process is simpler easy to operate.

The invention discloses a modeling method of a mouse hypertensive cerebral hemorrhage model, which comprises the following steps of: puncturing and taking blood from the left ventricle of a mouse, exposing a skull surgery field by wiping and cleaning soft tissues covering the skull, drilling after determining a needle insertion point on the surface of the skull, injecting autologous blood at the drilling position through a brain stereotaxic instrument, and then injecting the autologous blood into the mouse hypertensive cerebral hemorrhage model; and after injection is completed, sealing the drilled hole with bone wax, disinfecting the incision, and suturing the skin. According to the method, arterial blood is taken through left ventricle puncture, the survival rate of a mouse is not reduced on the premise that sufficient arterial blood is extracted, autologous arterial blood is accurately injected back into the tail shell core of the basal segment in the brain through a mouse brain locator, and stable hematoma is formed. The method provides guarantee for subsequent experiments, is beneficial to experimental contrast research, is very similar to clinical pathological changes and disease outcome of hypertension patients, and has important significance on disease outcome and treatment schemes after cerebral hemorrhage.

The invention discloses an individualized brain space stereo positioning technology, by introducing a face into the outer surface of the head, Concept of Axis and Angle, Repartition Name. The three-dimensional stereoscopic structure of four faces, five axes and two angles, which is composed of the operation face, three auxiliary locating faces, five axes and two angles, is acquired. Then the imagedata of the skull surface is obtained from the head CT, and the three-dimensional stereoscopic structure of four faces, five axes and two angles of the skull is printed into an integral skull surfacecomponent by using 3D printer. The three-dimensional stereoscopic structure of four faces, five axes and two angles of the skull is obtained. Complete reduction of the head surface component and theskull surface, so that the points on the operative surface and the points on the skull surface component completely coincide, assisting minimally invasive diagnosis, interventional treatment of braindiseases. The invention can realize multi-needle track, different angles and multi-point stereoscopic positioning of brain space from extracranial to intracranial brain pathological changes at the same time.

The invention discloses a skull optical clearing reagent and a reversible skull tissue optical clearing method, belonging to the technical field of bioimaging. The optical clearing reagent comprises a first solution and a second solution, wherein the first solution is an alcohol solution having the mass concentration being 25-30 % and composed of an amide organic compound and a derivative of the amide organic compound; the second solution comprises a water solution of an anionic surfactant, and a water-soluble penetration enhancer, the mass concentration of the water solution of the anionic surfactant is 15-20 %, and the use amount of the water-soluble penetration enhancer is 5-10 % of the total volume of the second solution. By dropwise adding the first solution and the second solution on the surface of the skull sequentially, the optical transparency of the skull tissue is realized, and the reagent can be used in an optical microscopic imaging system for imaging. With the reagent and the method, the nondestructive and non-invasive transparent skull window is established, the high-resolution imaging of a cortex microvessel system is realized, the operation is simple, the imaging quality is high, and the repeated imaging for a plurality of times can be realized.

The invention relates to a skull surface exact orientation device, belonging to a medical appliance for exactly orientating the encephalic focus. The skull surface exact orientation device comprises left, right plate for sticking to the two sides of the skull, earplug levers respectively fixed on the inner sides of the left, right plate and for inserting into the porus acusticus externus and playing a role of positioning, lines symmetrically disposed on the left and right plate and for CT scanning and positioning, wherein the two orientation base lines are disposed in 45 degree, horizontal scanning base line is normal to the orientation base line, and the extension lines of the three lines are crosses at the middle point of the superior border of the earplug lever and the two verification base lines with the given and same length are disposed in 22.5 degree with the horizontal scanning base line; two observation windows are set at the scanning base lines on the left and right plate and a orientation window is set at the middle point of the tie line of the inferior extremity of the two verification base lines. The skull surface exact orientation device has features of no wound, convenient operation, accurate orientation, low cost, being extensively used in clinical treatment.

The invention relates to the technical field of biomedical engineering, in particular to a skull prosthesis and a manufacturing method of the skull prosthesis , the skull prosthesis comprises a first prosthesis sheet, a second prosthesis sheet and a covering edge, and the first prosthesis sheet is laid on the surface of a skull and blocks a to-be-restored opening; the second prosthesis sheet is arranged in a to-be-restored opening of the skull, and the first prosthesis sheet and the second prosthesis sheet are connected through a plurality of supporting pieces; the covering edge is annularly arranged on the peripheral surfaces of the first prosthesis sheet and the second prosthesis sheet. According to the skull prosthesis body, a double-layer structure is adopted, growth and healing of to-be-restoredsoft tissue at a wound are facilitated, and the first prosthesis sheet and the second prosthesis sheet are annularly provided with the covering edges, so that the edge of the prosthesis body is soft, and wound healing is facilitated.

The invention discloses a registration method of a framed stereotactic system, which comprises the following steps of: 1) extracting head information from a CT (Computed Tomography) or MRI (Magnetic Resonance Imaging) image sequence to form a full data set H; (2) the head is rigidly fixed to a base ring of the stereotactic system with the frame; (3) fixing a collector on an object carrier, and collecting a three-dimensional data set of the skin surface contour or the skull surface contour; and (4) registering the three-dimensional data set in the step (3) and the full data set H in the step (1) so as to obtain a coordinate conversion relation from the CT or MRI image space to the operation space and finish registration. According to the method, the defects that in the stereotactic orientation of the frame, the frame must be firstly installed and then positioned and scanned or the installation position of the frame cannot be readjusted after the positioned and scanned are overcome, the traditional operation process is optimized, the clinical convenience and the operation safety are greatly improved, and the effectiveness of the classical technology is well preserved.

The invention provides a skull photon transparentizing treatment method and application thereof. The treatment method comprises the following steps that a compact bone substance loosening agent is added to the skull surface for treatment, and the compact bone substance loosening agent is selected from collagenase, trypsin and disodium edetate dehydrate; the skull surface treated with the compact bone substance loosening agent is cleaned; a high-refraction-index water-soluble reagent is added to the cleaned skull surface for treatment, and the skull with the relatively uniform refraction index is obtained. The skull structure treated through the method becomes transparent, and can be used for living body two-photon microimaging, and high-resolution imaging of cortex nerves and microvascular structures is achieved.

The invention discloses a skull dura separation device, comprising an arc sheath and an inner core, the inner core is movably connected inside the arc sheath, one end of the inner core is provided with a tip head, and the outer surface of the inner core is close to the tip One side of the head is provided with a spreading bag, the other end of the inner core is fixedly connected with an injection head, and one side of the pointed head is tilted upward at an angle of 15 degrees. The skull dura mater separation device, when the craniotomy is drilled, the device is inserted under the skull and on the dura, and the direction is changed to be parallel to the skull surface through the radian sheath, and the dura is separated from the skull by pushing the inner core. It is convenient to separate the dura mater. During the insertion process, the medical staff can know the depth of the insertion of the two through the nicks on the surface of the inner core and the curved sheath and the evaluation sheet, and the staff can use the injection tube to inflate through the injection head, The expansion bag is inflated and separated by the force of its expansion.

The invention provides a laser locator for brain stereotaxic positioning, relates to the technical field of test tools, and solves the problems that in the prior art, when a brain stereotaxic instrument is used, positioning is inaccurate and infection is possibly caused when a marker pen is used for marking the position on the surface of a skull. The laser positioner comprises a base connector, a position adjusting mechanism and a laser generator, the laser generator is connected with the base connector through the position adjusting mechanism, the base connector is connected with the brain stereotaxic apparatus, and the spatial position of the laser generator can be adjusted through the position adjusting mechanism. When the laser locator is used, the laser locator is firstly fixed on a brain stereotaxic instrument base through a base connector; then a target point is found on the surface of the skull through the datum point by utilizing a brain stereotaxic instrument, and when the needle point is close to the surface of the skull, the position adjusting mechanism is adjusted, so that a laser point emitted by the laser generator is accurately positioned on the skull below the needle point of the microsyringe, and whole-course real-time marking can be realized in the subsequent polishing process.