47 results about "Skull surface" patented technology

A system and method are provided for using a computer system to assist in planning a trajectory (960A, 960B) for a surgical insertion into a skull. The method comprises providing the computer system with a three-dimensional representation of the skull and of critical objects located within the skull, wherein the critical objects comprise anatomical features to be avoided during the surgical insertion. The method further comprises providing the computer system with a target location (770, 970) for the insertion within the skull. The method further comprises generating by the computer system a first set comprising a plurality of entry points, each entry point (760) representing a surface location on the skull, and each entry point (760) being associated (2D) with a trajectory (960A, 960B) from the entry point (760) to the target location (770, 970). The method further comprises discarding by the computer system entry points from the first set to form a second, reduced set comprising a plurality of entry points, wherein an entry point (760) is discarded from the first set of entry points if the entry point (760) has an entry angle which fails a condition for being substantially perpendicular to the skull surface. For each entry point (760) in the second set, the computer system assess the entry point (760) against a set of one or more criteria, wherein the set of one or more criteria includes a risk factor based on the separation between the critical objects and the trajectory (960A, 960B) which is associated with said entry point (760)). This risk factor may be calculated by integrating f(x) along the trajectory (960A, 960B) associated (2D) with the entry point (760), where x represents distance along the trajectory (960A, 960B) to a sample point, and f(x) is a function based on distance from the sample point at distance x to a critical object which is nearest to said sample point.

The invention provides a craniotomy device and method for brain surgery, comprising: a positioning sleeve, the positioning sleeve is provided with an adjusting hoop that is threadedly matched with the adjusting hoop, and a There is a scale, and a sliding sleeve with a clearance fit is provided outside the adjusting hoop, and a righting limit sleeve that is rotationally connected is provided at the lower part of the sliding sleeve, and a drill pipe is arranged inside the righting limit sleeve, and a universal leveling joint is provided at the lower end of the drill pipe in turn And the casing drill, the casing drill is provided with a suction seat. In the present invention, the contact surface between the strip-shaped annular teeth and the skull is small, and the fit with the skull surface is good, so that all the annular teeth are in uniform contact with the skull surface, and the vibration force is extremely small during drilling, which can smoothly The skull hole is drilled through, and the phenomenon of drill sticking will not occur, and the drilling process is relatively simple and smooth; at the same time, the righting limit sleeve drill will not invade the meninges, the difficulty of drilling on the skull is extremely low, and the drilling process is simpler easy to operate.

The invention discloses a skull optical clearing reagent and a reversible skull tissue optical clearing method, belonging to the technical field of bioimaging. The optical clearing reagent comprises a first solution and a second solution, wherein the first solution is an alcohol solution having the mass concentration being 25-30 % and composed of an amide organic compound and a derivative of the amide organic compound; the second solution comprises a water solution of an anionic surfactant, and a water-soluble penetration enhancer, the mass concentration of the water solution of the anionic surfactant is 15-20 %, and the use amount of the water-soluble penetration enhancer is 5-10 % of the total volume of the second solution. By dropwise adding the first solution and the second solution on the surface of the skull sequentially, the optical transparency of the skull tissue is realized, and the reagent can be used in an optical microscopic imaging system for imaging. With the reagent and the method, the nondestructive and non-invasive transparent skull window is established, the high-resolution imaging of a cortex microvessel system is realized, the operation is simple, the imaging quality is high, and the repeated imaging for a plurality of times can be realized.

The invention relates to a manufacturing method for a multilayer-uneven-structure brain hematoma model, and belongs to the technical field of biomedicine. The manufacturing method includes the following steps that S1, human-body brain data is scanned through nuclear magnetic resonance to obtain three-dimensional structure data of the skull surface, three-dimensional structure data of the grey matter surface and three-dimensional structure data of the white matter surface; S2, the three-dimensional data of the skull, the three-dimensional data of the grey matter and the three-dimensional data of the white matter are led into 3dsmax to be merged, subjected to model detail reducing and shell adding treating; S3, the model is manufactured according to the data obtained in the S2; S4, cavities corresponding to tissue are filled with corresponding simulation materials, namely, materials with the dielectric constant and the electric conductivity equal to corresponding tissue, and manufacturing of the model is completed; S5, a small rubber bag is arranged in the model, an injector is connected with the small rubber bag arranged in the brain model through a plastic conduit, and the volume of blood in the rubber bag is adjusted to simulate variation of hematoma. According to the manufacturing method, manufacturing is convenient, the result of electromagnetic waves passing through the multilayer-uneven-structure brain can be really responded, the actual condition of brain hematoma can be really simulated, and the manufacturing method can be used in the brain hematoma monitoring technology based on electromagnetism.

The invention provides a skull photon transparentizing treatment method and application thereof. The treatment method comprises the following steps that a compact bone substance loosening agent is added to the skull surface for treatment, and the compact bone substance loosening agent is selected from collagenase, trypsin and disodium edetate dehydrate; the skull surface treated with the compact bone substance loosening agent is cleaned; a high-refraction-index water-soluble reagent is added to the cleaned skull surface for treatment, and the skull with the relatively uniform refraction index is obtained. The skull structure treated through the method becomes transparent, and can be used for living body two-photon microimaging, and high-resolution imaging of cortex nerves and microvascular structures is achieved.

The invention discloses a skull dura separation device, comprising an arc sheath and an inner core, the inner core is movably connected inside the arc sheath, one end of the inner core is provided with a tip head, and the outer surface of the inner core is close to the tip One side of the head is provided with a spreading bag, the other end of the inner core is fixedly connected with an injection head, and one side of the pointed head is tilted upward at an angle of 15 degrees. The skull dura mater separation device, when the craniotomy is drilled, the device is inserted under the skull and on the dura, and the direction is changed to be parallel to the skull surface through the radian sheath, and the dura is separated from the skull by pushing the inner core. It is convenient to separate the dura mater. During the insertion process, the medical staff can know the depth of the insertion of the two through the nicks on the surface of the inner core and the curved sheath and the evaluation sheet, and the staff can use the injection tube to inflate through the injection head, The expansion bag is inflated and separated by the force of its expansion.