49 results about "Tocophersolan" patented technology

An emulsion of α-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans via various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated α-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of α-tocopherol.

The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of α-tocopheryl acetate; α-tocopheryl acetate and about 0.5% aqueous component; or α-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.

The invention provides a less-harmful nontoxic rubber vehicle sealing strip which has excellent processability and physical properties and belongs to an environment friendly sulfidizing system. Main raw materials are as follows: 200 plus or minus 10 portions of ethylene propylene diene methylene, and 150 plus or minus 10portions of carbon black; 20 plus or minus 2 portions of light super fine calcium carbonate and 30 plus or minus 3 portions of talc as fillers; 20 plus or minus 2 portions of high-flash paraffin oil or styrene / Alpha-methyl styrene / vinyl toluene terpolymer as a softener; 10 plus or minus 1 portions of aluminum hydroxide as a flame retardant; 5 plus or minus 0.5 portions of zinc oxide and 2 plus or minus 0.2 portions of stearic acid as active agents together; 4 plus or minus0.4 portions of polyethylene glycol of a hydroxyl polar group as an additive; 5 plus or minus 0.5 portions of calcium oxide as a neutralizer; 4 plus or minus 0.4 portions of nitrogen-free sulfidationmaterial which is mainly sulphur; and 0.3 plus or minus 0.03 portion of Alpha-tocopherol as an inhibitor. The less harmful nontoxic rubber vehicle sealing strip can not only reduce environmental pollution, but also maintain reasonable cost.

Water-soluble compositions comprising a lipophilic compound and a solubilizing agent of the general formula:{X—OOC—[(CH2)n—COO]m}p—Y  (I)wherein:X is a residue of a hydrophobic moiety,Y is a residue of a hydrophilic moiety,p is 1 or 2,m is 0 or 1, andn is an integer greater than or equal to 0are disclosed. The lipophilic compound is preferably selected from the group consisting of water-insoluble ubiquinones, ubiquinols, vitamins, provitamins, polyene macrolide antibiotics, and mixtures thereof. The hydrophobic moiety is preferably a sterol or a tocopherol and the hydrophilic moiety is preferably a polyalkylene glycol. In some embodiments, the sterol is cholesterol or sitosterol, the tocopherol is α-(+)-tocopherol, the polyalkylene glycol is a polyethylene glycol or its methyl monoether having an average molecular weight between 400 and 1000, p is equal to 1 or 2, m is equal to 0 or 1 and n is an integer between 2 and 18.

The present invention relates to a deterioration preventive for a flavor component, which is an oil-in-water and / or -polyhydric alcohol type emulsion, comprising an extracted tocopherol, wherein d-δ-tocopherol is contained in an amount of 45% by weight or more of a total tocopherol, ferulic acid and / or a derivative thereof, and a polyglycerol fatty acid ester; a deterioration preventive for a flavor component, which is an oil-in-water and / or -polyhydric alcohol type emulsion, comprising (A) the above-mentioned extracted tocopherol, (B) ferulic acid and / or a derivative thereof, and (C) an emulsifying agent having an HLB of 9 or more; a flavor for foodstuff, comprising the above-mentioned deterioration preventive; an emulsion flavor for foodstuff, comprising the above-mentioned extracted tocopherol, a catechin; and a polyglycerol fatty acid ester; and foodstuff comprising the above-mentioned deterioration preventive for a flavor component, the above-mentioned flavor for foodstuff, or the above-mentioned emulsion flavor for foodstuff.