The invention belongs to the technical field of pet bath products, and particularly relates to a pet body wash and a preparation process thereof. The pet body wash takes radix sophorae flavescentis, neem tree roots, macleaya cordata, radix angelicae, radix stemonae, realgar, cactus, indigo, cortex phellodendri, rhubarb and rosemary as medicinal materials and has reasonable compatibility; the prepared body wash has higher detergency, is easy to clean and rinse and has no irritation to the skin, cleaned skin hair is smooth and soft, cool and refreshing, elastic and fragrant. The pet body wash also has the effects of anti-itch, anti-inflammatory, and promotes skin renewal and has particularly remarkable skin cleaning and nursing effects. At the same time, the pet body wash can significantly reduce the number of colonies on the surface of the skin, has a good sterilization effect, has effects of astringing wounds and nourishing the skin, and can make the skin dry and clean and the hair shiny by long-term use.