The invention relates to an isopropanolamine production method and mainly solves problems of high device investment, large floor space, high dewatering energy consumption, large quantity of byproductsand the like in use of a long tube reactor with water serving as a catalyst in the prior art. The isopropanolamine production method is characterized in that a tubular fixed-bed reactor and a heat insulating tube reactor are adopted to guarantee complete conversion of epoxypropane; anhydrous liquid ammonia and epoxypropane are used as reaction raw materials in the tubular fixed-bed reactor, and high-concentration ammonium hydroxide and epoxypropane are used as raw materials in the heat insulating tube reactor; in the tubular fixed-bed reactor, by circulating hot water heat removal, heat removal hot water is used for preheating raw materials and pressure-reduced reaction products to realize reaction heat recovery, the reaction products sequentially passes through an ammonia recovery towerand a dewatering tower to recover ammonia and water, and overhead gas of the dewatering tower is used for preheating pressure-reduced reaction raw materials to reduce energy consumption. The method islow in byproduct quantity, equipment investment and device energy consumption can be reduced, and the method can be applied to industrial production of isopropanolamine.