A titanium alloy plate welding method capable of improving welding performance comprises the following steps that S1, a Ti6Al4V titanium alloy plate with the thickness ranging from 2 mm to 4 mm is taken, a V-shaped welding groove is formed in the position to be welded, a butt joint is formed, the groove angle of the welding groove ranges from 18 degrees to 22 degrees, the width of an upper opening of the groove ranges from 0.8 mm to 1.2 mm, the groove gap ranges from 0 mm to 1 mm, and the truncated edge of the groove ranges from 0.1 mm to 0.5 mm; s2, metal particles are weighed according to the mass percent of 6wt% of Al, 4wt% of V, 0.1-0.7 wt% of Ce and the balance Ti, an alloy ingot is prepared through vacuum induction melting, and then the alloy ingot is machined into a transition layer matched with the welding groove; s3, the transition layer is placed in a welding groove of the Ti6Al4V titanium alloy plate butt joint, and a to-be-welded welding joint is formed; s4, pulse laser welding is conducted on the to-be-welded welding joint; according to the welding process parameters, the pulse frequency ranges from 20 Hz to 30 Hz, the pulse width ranges from 23 ms to 27 ms, the welding speed ranges from 22 mm/s to 28 mm/s, the laser base value power ranges from 2800 W to 3200 W, the laser peak power ranges from 3800 W to 4200 W, and the protective argon flow ranges from 12 L/min to 20 L/min. The welding method is low in cost, high in efficiency and good in joint quality, and the obtained welding seam is excellent in performance.