The invention relates to a health-care traditional Chinese medicine preparation having the effects of invigorating brain, refreshing, invigorating spleen-stomach and replenishing qi and a preparation method thereof. The traditional Chinese medicine preparation is prepared from, by weight, 5-10 parts of codonopsis pilosula, 10-20 parts of radix astragali, 10-20 parts of Chinese wolfberry fruits, 10-20 parts of Chinese yam, 10-20 parts of radix angelica sinensis, 10-20 parts of white paeony root, 10-20 parts of platycodon grandiflorum, 10-20 parts of radix adenophorae, 20-30 parts of radix ophiopogonis, 20-30 parts of fleece-flower root, 20-30 parts of rehmannia glutinosa, 5-10 parts of radix scrophulariae, 10-20 parts of longan pulp, 20-30 parts of red jujubes, 10-20 parts of black dates, 10-20 parts of radix morindae officinalis, 10-20 parts of eucommia bark, 20-30 parts of achyranthes bidentata, 10-20 parts of radix dipsaci, 10-20 parts of acorus calamus, 10-20 parts of polygala tenuifolia and other traditional Chinese medicine raw materials. The health-care traditional Chinese medicine preparation having the effects of invigorating brain, refreshing, invigorating spleen-stomach and replenishing qi and also has the advantages of tonifying heart, invigorating the kidney, strengthening Yang, delaying senescence and the like.