The invention discloses a preparation method of 
gastrodia elata 
wine. The method comprises the following steps: crushing 
gastrodia elata, adding active dry 
yeast of glucose and 
distilled water, fermenting, filtering and distilling filtrate at reduced pressure to obtain distillate B; filtering residual 
mother liquor by an 
ultrafiltration membrane to obtain filtrate C; taking 10-12 parts by volume of 
white spirit, 0.5-1 part by volume of distillate and 1-1.5 parts by volume of filtrate; evenly mixing, placing at 
room temperature for 24 hours; and filtering by the 
ultrafiltration membrane to obtain the filtrate, namely the 
gastrodia elata 
wine. Compared with the prior art, the method has the advantages that 
gastrodia elata wine mash is prepared by adopting a biological enzymatic transformation method; and a little 
gastrodia elata wine mash and the 
white spirit are blended, so as to obtain the transparent 
gastrodia elata wine with good taste, mellow 
flavor and certain health-care function. An experiment proves that the gastrodia elata wine has significant effects of easing pain and calming mind, and can effectively promote sleeping quality. Furthermore, the gastrodia elata wine disclosed by the invention is reasonable in preparation method, simple to operate, and low in production cost; the content of 
chemical ingredients of the gastrodia elata in the blended wine is low, so that the administration 
dose is not limited; and the gastrodia elata wine can be taken everyday.