The invention relates to a pure Chinese herbal medicine detoxification agents with tranquilization and body-building function, comprising a first prescription for removing the drug addiction and a second prescription for removing the heart addiction; wherein, the weight account of the two prescription are as follows: the first prescription: astragalus 70 to 110, lanceolata 70 to 110, angelica sinensis 40 to 80, Duzhong 70 to 110, Rhizoma Gastrodiae 20 to 40, rhizoma corydalis 70 to 110, Baishu 40 to 80, Fushen 70 to 110, dried ginger 40 to 80, senna leaf 22 to 55, hawthorn 70 to 110, Tiandong 35 to 65, liriope 25 to 55, Shudi 30 to 70, nut grass 30 to 70, cassia 30 to 70, centipede 15 to 35; the total weight account is 750 to 1360; the second prescription: astragalus 70 to 110, lanceolata 70 to 110, angelica sinensis 40 to 80, Duzhong 70 to 110, Rhizoma Gastrodiae 20 to 40, rhizoma corydalis 70 to 110, Baishu 40 to 80, dried ginger 40 to 80, hawthorn 70 to 110, Tiandong 35 to 65, Shudi 30 to 70, nut grass 30 to 70, cassia 30 to 70; the total weight account is 615 to 1105. The pure Chinese herbal medicine detoxification agent has the advantages of effective drug addiction removal, without side effect, without drug dependence, and blood nourishment and tranquilization as well as health improvement and body-building.