1 results about "Chlorin e6" patented technology

The application belongs to the technical field of biological medicine, and particularly relates to a neutrophil biomimetic vesicle nano preparation for targeting colorectal cancer and a preparation method and application thereof. The application provides a neutrophil biomimetic vesicle nano preparation for targeting colorectal cancer, wherein the neutrophil biomimetic vesicle nano preparation comprises neutrophil biomimetic vesicles, tumor-targeting peptides and photosensitizers; the tumor-targeting peptides are modified on the surface of the neutrophil biomimetic vesicles; the photosensitizers are loaded in the neutrophil biomimetic vesicles; and the photosensitizers comprise chlorin e6. The neutrophil biomimetic vesicle nano preparation has a stable core-shell structure, can effectively protect the activity of the photosensitizers, prevent leakage and aggregation quenching of the photosensitizers, and specifically enriches the photosensitizers (Ce6) in tumor cells, so that targeted delivery of the drug is realized. The problems of poor targeting of the existing photosensitizers, large toxic and side effects, short circulation time of the synthetic nano carriers, poor biocompatibility and the like are solved.