A composite factor synthetic transdermal absorption mask and its production method. The invention utilizes the composite factor to accelerate the proliferation and division speed of human cells, replace aging dead cells, and increase the number of newborn cells, so as to achieve the mechanism of keeping the skin young. By selecting sterilized milk, Quail egg extract, grape seed extract, collagen polypeptide extract, snail secretion, hyaluronic acid, tomato juice seven substances, a self-made compound factor; then add propolis, lemon juice, angelica, ginseng, pearl powder, almonds , rice water, egg white, silver nanoparticles, seaweed particles, natural mineral water, aloe vera, glycerin to synthesize a high-efficiency transdermal absorption mask with antibacterial, anti-wrinkle, whitening, and moisturizing properties. At the same time, environmentally friendly materials are selected as the mask carrier. The invention has the characteristics of skin penetration, easy absorption, moisturizing, safety and environmental protection.