43 results about "Oncology patients" patented technology

The invention belongs to preparation of biological cell formulations, and in particular relates to a preparation method of dendritic cell (DC) vaccine loaded with autologous tumor associated holoantigen. The preparation method comprises the following steps: preparing the autologous tumor associated holoantigen, collecting and separately culturing DCs, impacting the DCs by the autologous tumor associated holoantigen, maturing the DCs and preparing autologous tumor antigen specific DC vaccine. The invention solves the problems in the prior art that the immunogenicity of tumor antigen is not strong enough, the antigen target spots are incomplete, the tumor antigens of most tumor patients are difficult to acquire, and the like. The DC vaccine provided by the invention has the advantages of effectively inducing tumor antigen specific cytotoxic T lymphocyte (CTL) in vitro and in vivo, efficiently generating specific cytotoxicity on tumors, having high overall effective rate and no obvious toxic side effects in clinical application, and the like.

The invention provides an oncology department nursing device. The oncology department nursing device comprises a nursing bed body, wherein supporting legs are arranged at the bottom of the nursing bedbody; universal wheels are arranged at the bottoms of the corresponding supporting legs; a translation track is formed in the outer edge side of the nursing bed body; a driving device is arranged onthe translation track; an isolation device is mounted on the translation track through the driving device; a control device is arranged at the top of the isolation device; the control device comprisescontrol buttons; a display screen is arranged on one side of the control device; an air purifier is further arranged in the isolation device; and the display screen and the air purifier are electrically connected with the control device. The oncology department nursing device is novel in design, good in nursing effect and beneficial to rehabilitation of tumor patients.

The invention relates to hericium erinaceus complex polysaccharide composition as well as a preparation method and application thereof. The hericium erinaceus complex polysaccharide composition is prepared from the following components in parts by weight: 0.5 to 5 parts of hericium erinaceus extract, 0.5 to 5 parts of agaricus blazei murill extract, 0.5 to 5 parts of poria cocos extract, and 0 to 5 parts of neutral radix notoginseng polysaccharides extract. The hericium erinaceus complex polysaccharide composition is helpful for improving the immunity of the patients with low immunity and tumor, improves the symptoms of mental malaise, body weakness, loss of appetite, nausea and vomiting, loose stool and diarrhea, dry stool, irritability and insomnia, and the like, effectively reduces the harm of radiotherapy and chemotherapy and surgery on cancer patients to extend the survival of cancer patients.

The invention relates to application of tamoxifen combined with rapamycin and ginsenoside Rg3 in preparing medicaments for treating liver cancer. When the tamoxifen is combined with the rapamycin and the ginsenoside Rg3 to treat the liver cancer, sensibility of liver cancer cells on chemotherapy can be improved. The tamoxifen inhibits activeness of an Akt to induce apoptosis of mammary epithelialcells. When an Akt access is activated, breast cancer cells are induced to generate drug resistance to the tamoxifen. The tamoxifen, the rapamycin and the ginsenoside can be used jointly to induce the apoptosis of tumor cells in a cooperation mode. Besides, the ginsenoside Rg3 can inhibit expression of vascular endothelial growth factors (VEGF) of the tumor cells to inhibit the formation of tumorvessels, further can inhibit expression of matrix metalloproteinases and interfere interaction of endothelial cells and extracellular matrixes to block infiltration and metastasis of tumors, improve thoroughness of operation treatment and reduce the rate of recrudescence and metastasis after an operation, and can improve self immunity of a tumor patient, inhibit tumor metastasis and reduce toxic and side effects of the tumor patient after the chemoradiotherapy.

A health-care food suitable for the patients of tumor, AIDS, rheumatoid arthritis, intestinal ulcer, etc to improve their immunity is prepared from chitosan (7.5-9 Wt portions), wall-broken ganoderma spore powder (0.5-1.5) and cordyceps (0.5-1).

The invention discloses a traditional Chinese medicine preparation for a patient suffering from pancreatic cancer to take after an operation. The traditional Chinese medicine preparation is prepared from raw materials in parts by weight as follows: 8-13 parts of spreading hedyotis herbs, 3-7 parts of water chestnuts, 6-12 parts of roots of symplocos sumuntia, 9-13 parts of roots of redfruit actionodaphne, 7-14 parts of flowers of fleshfingered citron, 5-10 parts of fructus livistonae, 8-12 parts of garden burnet roots, 6-13 parts of giant knotweed rhizomes, 4-9 parts of Japanese st. john's wort herbs, 3-6 parts of roots of Hongkong caper, 7-12 parts of herbs of smallflower beggarticks, 5-11 parts of leaves or roots of littlefruit uvaria, 8-14 parts of roots of evans begonia, 6-11 parts of dragonhead herbs and 4-12 parts of herbs of corymb woodsorrel. The traditional Chinese medicine preparation has the excellent effects as follows: a prepared medicine has remarkable advantages in promotion of postoperative rehabilitation of the patient suffering from pancreatic cancer, reduction of operative complications, improvement of immunity, prolonging of lifetime and the like; the medicine is scientifically matched, has a good treatment effect and is free of side effects, and the burden of the patient can be effectively reduced due to low treatment expenses.

The invention belongs to preparation of biological cell formulations, and in particular relates to a preparation method of dendritic cell (DC) vaccine loaded with autologous tumor associated holoantigen. The preparation method comprises the following steps: preparing the autologous tumor associated holoantigen, collecting and separately culturing DCs, impacting the DCs by the autologous tumor associated holoantigen, maturing the DCs and preparing autologous tumor antigen specific DC vaccine. The invention solves the problems in the prior art that the immunogenicity of tumor antigen is not strong enough, the antigen target spots are incomplete, the tumor antigens of most tumor patients are difficult to acquire, and the like. The DC vaccine provided by the invention has the advantages of effectively inducing tumor antigen specific cytotoxic T lymphocyte (CTL) in vitro and in vivo, efficiently generating specific cytotoxicity on tumors, having high overall effective rate and no obvious toxic side effects in clinical application, and the like.

The invention belongs to the field of traditional Chinese medicines, and relates to a composition for improving or treating acute radioactive oropharyngeal mucositis and a preparation method and application thereof. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of improving or treating discomfortable symptoms of acute stage reaction of the oropharyngeal mucositis such as dryness and pain of oropharynx, red and swelling, erosion, ulcer and the like caused by radiation chemotherapy. The composition for improving or treating the acute radioactive oropharyngeal mucositis is characterized by being prepared from the following crude drugs by weight proportion: 12-18 parts of rhizoma phragmitis, 8-12 parts of flos lonicerae, 12 to 18 parts of fructus momordicae, 7 to 12 parts of herba menthae, 1 to 3 parts of endothelium corneum gigeriae galli, and 3 to 8 parts of auricularia polytricha or white fungus. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of nourishing Yin and generating body fluid, diminishing inflammation, reducing phlegm, increasing appetite, greatly improving the discomfortable symptoms of the acute stage reaction of the oropharyngeal mucositis such as the dryness and pain of oropharynx, the red and swelling and the like, and being suitable for patients with head and neck cancer in the period of radiotherapy and chemotherapy to drink. In particular, the composition for improving or treating the acute radioactive oropharyngeal mucositis is prepared as a solid beverage of the traditional Chinese medicine, and has the advantages of being convenient to brew, good in taste and simple in production process.

The present invention relates to a nutritional composition comprising dietary fibre for stimulating natural killer cell activity, in particular in patients infected with HIV, oncology patients and elderly.

The invention discloses an immunity enhancing reagent comprising AAVs carrying molecule encoding genes of antibodies at immunodetection points, wherein the immunodetection points are one or several from PD-1, PD-L1 and CTLA-4. The AAVs carrying the molecule encoding genes of the antibodies at different immunodetection points are combined with each other, T cells, natural killer cells, cytotoxic T lymphocytes or cell factor induced killer cells and other immune cells are infected in vitro, and the antibodies at the immunodetection points are expressed and secreted after the infected immune cells are fed back to bodies of patients suffering from tumors, so that the combination of receptors at the immunodetection points and ligands of the receptors is blocked, the transfer of an immunosuppression signal is effectively blocked, the immune tumor suppression microenviroment is destroyed, the immune cell killing capacity is improved, and furthermore the curative effect of adoptive immune therapy is improved.

The invention discloses a nursing medicament for relieving cancer patient chemotherapy side reactions. The medicament is prepared from, by weight, 8-14 parts of centella, 6-9 parts of tremmella, 9-15 parts of rehmannia glutinosa, 5-10 parts of polygonum multiflorum, 4-11 parts of hawthorn fruits, 7-13 parts of saussurea involucrate, 6-15 parts of lotus seeds, 6-9 parts of medical stone, 1-5 parts of corn and 1-9 parts of bunge cherry seeds. According to the medicament, the channel affinity medicine with the high spicy passing effect is selected, the medicine directly acts on an effected part, main and collateral channels are transferred, the effects of improving immunity, enhancing appetite and relieving pain are achieved, and the medicament can be used for relieving cancer patient chemotherapy side reactions such as diarrhea, alopecia and fatigue.

The invention discloses a chemotherapy nursing device for gynecological tumor patients, which comprises a telescopic rod 1 and a telescopic rod 2, a connection plate is fixed between the telescopic rod 1 and the telescopic rod 2, and a fixing assembly is arranged at the lower ends of the telescopic rod 1 and the telescopic rod 2, There is a support plate between the upper ends of the telescopic rod 1 and the telescopic rod 2. The two sides of the support plate are respectively provided with chute 1 and chute 2. The upper end of the telescopic rod 1 is provided with a groove 1 on the side wall, and a motor is fixed inside the groove 1. 1. The output shaft of the motor 1 is fixed with a box slidingly arranged in the chute 1. The side wall of the telescopic rod 2 is provided with a groove 2. The motor 2 is fixed in the groove 2. The output shaft of the motor 2 is fixed with a gear 1. , a rack meshing with gear one is fixed inside the second chute, a protective cover is provided on one side of the support plate, sliding groove one and sliding groove two are opened on the support plate, and inserting block one and inserting block two are fixed on the protective cover, Insert block 1 and insert block 2 are slidably arranged in slide groove 1 and slide groove 2 respectively, which have the advantages of fixing the patient's hand and preventing external injuries.