251 results about "Sphingomonas elodea" patented technology

A novel dosage form. The dosage form is presented in particulate form and before oral ingestion the particulate material is subjected to an aqueous medium, whereby it is converted to a semi-solid form by swelling or gelling of one or more of the components, especially of a gellan gum, of the particulate matter. The invention also relates to a vehicle for oral administration of one or more active substances, the vehicle comprising a gellan gum arranged in a configuration allowing optimal water diffusion so that upon addition of a predetermined amount of an aqueous medium, without the necessity of applying shear forces or other mixing forces, within a time period of 5 minutes or less swells and/or gels and the texture of the swelled vehicle being similar to that of a soft pudding and having a viscosity of at least about 10,000 cps as measured by a Brookfield Viscometer with a #4 LV spindle at 6 rpm and at 20-25° C. In one embodiment of the invention, the particulate matter can be moulded into a desired shape or pressed onto a dispensing unit such as a spoon.

A low calcium sensitive (calcium stable) high acyl gellan gum is prepared for enhanced colloidal stability in beverages. The low calcium sensitive high acyl gellan gum has superior suspension performance for colloidal stability compared to other high acyl gellan gums. The low calcium sensitive high acyl gellan gum is prepared by adjusting the pH of a gellan fermentation broth (polymer solution) prior to pasteurization and reducing the pasteurization hold time compared to conventional pH levels and hold times.

The invention relates to high performance gellan gum compositions having a 0.1% curdmeter gel strength of at least about 117 g/cm², i.e. from about 117 g/cm² to about 400 g/cm². The high performance gellan gums have a low acyl content but an increased molecular weight. One embodiment of the invention also relates to processes for producing high performance gellan gums having high clarity. The invention further relates to food and non-food industrial products comprising high performance gellan gums.

DNA constructs and genetically engineered microbial strains constructed using these DNA constructs, which produce a nuclease enzyme with specificity for DNA and/or RNA, are provided. These strains secrete nuclease into the periplasm or growth medium in an amount effective to enhance productivity and/or recovery of polymer, and are particularly suited for use in high cell density fermentation processes. These constructs are useful for modifying microbial strains to improve production and recovery processes for polymers such as intracellular proteins, such as enzymes, growth factors, and cytokines; for producing polyhydroxyalkanoates; and for producing extracellular polysaccharides, such as xanthan gum, alginates, gellan gum, zooglan, hyaluronic acid and microbial cellulose.

Provided is a pharmaceutical composition for oral administration containing a 5-HT.₃ receptor antagonist, which is suitable for self-medication because of good preservation stability, low synthesis, good uniformity and good external appearance, and good smoothness in throat, and easiness to be taken. Concretely, it is a jellied pharmaceutical composition for oral administration containing a 5-HT.₃ receptor antagonist, a gelatinizing agent, and water; and having a pH of 7 or less. In particular, there is provided the pharmaceutical composition, where the gelatinizing agent is carrageenan, pectin, agar, alginic acid, sodium alginate, gelatin, manna, Kodak, konjakmannan, glucomannan, chitosan, xanthan gum, tamarind seed polysaccharide, gellan gum, karaya gum, or cassia gum, or preferably the pharmaceutical composition further containing a thickener.

The use of gellan gum in combination with carboxymethyl cellulose (cellulose gum) in acidified protein beverages is described. Acifidied protein beverages comprising a combination of cellulose gum and gellan gum and methods to prepare these beverages are also described.

Mutational inactivation of proteins involved in para-cresol production in certain milk products results in improved taste and odor. The undesirable para-cresol forms over time as a result of enzymes produced by the bacterium that produces gellan gum. Since the gellan is typically used in a relatively unpurified form, the enzymes are added to the milk along with the gellan. Inactivation of the enzymes is a genetic means of eliminating the enzymes without requiring any additional purification or processing.

The invention relates to a method for extracting low-acyl gellan gum suitable for a tissue culture medium, which comprises the following steps of: acyl removal treatment and enzyme treatment of a gellan gum fermenting fluid, flocculation of the gellan gum in a low-acyl state by bivalent or multivalent metal cation, clarification treatment of a gellan gum solution, dehydration treatment of the gellan gum solution, decoloring and ion exchange treatment, addition of a chelator /acid system to chelate bivalent cation possibly added during using the gellan gum and relative stability keeping of pH value, drying, and pulverization. The invention also provides the low-acyl gellan gum prepared by the method; the low-acyl gellan gum has the characteristics of good product appearance, good transmittance and high gelatinization strength which include the following properties: the chrominance is more than 83 percent; the transmittance is over 90 percent; and simultaneously, the gelatinization strength is between 400 and 650 g/cm.

The invention discloses a gellan gum gel-based ceramic gel injection molding method, which belongs to the technical field of inorganic non-metal ceramic. The method comprises the following steps of: mixing ceramic powder, a dispersant and water to prepare ceramic slurry; defoaming under vacuum and then preserving heat in a water bath of 50-70 DEG C for 10-20 minutes; meanwhile, heating mixture of gellan gum and water to 70-80 DEG C to prepare uniform and stable aqueous solution with mass fraction of 1-5 percent; and adding the gellan gum aqueous solution and the aqueous solution containing calcium ions or magnesium ions with mass fraction of 1-10 percent into the prepared ceramic slurry and stirring for 5-10 minutes; finally preparing a ceramic blank in an imperforated mold; and sintering the ceramic blank to obtain a compact ceramic sintered body. The method provided by the invention has the advantages of economy, environmental friendliness, easiness in operation and convenience in industrial production, and the prepared compact ceramic sintered body has superior performance and wide application.

The invention discloses a sphingomonas paucimobilis strain and an application thereof. The sphingomonas paucimobilis strain is named as sphingomonas paucimobilis QHZJUJW, with the preservation number: CGMCC No.7783. The stain is endophyte derived and screened from seeds of wild microporous grass in Qinghai-Tibet Plateau, can be used for industrialized production of gellan gum and provides a new way for the industrialized production of the endophyte and gellan gum.

The invention relates to a preparation method of microbe polysaccharide Gellan gum belonging to the microbe fermentation production field. The method comprises steps of preparing the slope strains, preparing the seed liquid, inoculating the seed liquid into the fermentation culture medium to ferment. The invention solves the problems of high production cost, low product yield (the density of the Gellan gum coarse polysaccharide is 1.3g/100ml) exiting in known technology. The invention employs starch as the carbon source for the second level expanding culture medium and fermentation culture medium, and has advantages of low cost, high yield. The density of the Gellan gum coarse polysaccharide is 1.5-1.6g/100ml when the fermentation is finished.

The invention relates to a posterior extraction method of Gellan gum belonging to the microbe fermentation production field. The method comprises steps of pretreatment of the fermentation liquor, deacylation, filtration, extraction of the flocculate, solid-liquid separation, drying and pulverization. The invention overcomes the shortcomings of high manufacturing cost, single variety existing in known technology. By the deacylation treatment with different added hypochlorite, Gellan gum with different acyl content can be obtained without destruction of the Gellan gum molecular structure to meet different need. The flocculant employs alkali metal or alkaline earth chloride to substitute for partial organic solvent to improve the production safe reliability.

The invention relates to a new type jointing cold glue, productive technology and usage. This invention possesses low organic solvent residual quantity (such as alcohol residual quantity is not more than 200ppm) and high gel strength, which is fit for many sites.

This invention relates to microorganism fermentation domain. It provides a post extraction method of acyl gellan. It consists of these steps: pretreatment of the fermentation solution, flocculent deposition; solid and liquid separation, dry, crush and so on. The invention resolves the problem of high acyl gellan gum, because it has been product by CPkeclo company of America, and its price is very high, characterized in that its cost is very low because of process is very simple, energy cost is low, material cost is low, and the quality reaches the FccIv standard of America.

The invention pertains to a liquid composition for preventing and/or treating memory decline and/or cognitive dysfunction, Alzheimer's, Parkinson's and/or dementia, said composition comprising: (i) at least 50 mg nucleoside and/or nucleotide per 100 ml; (ii) between 0.2 and 10 grams protein per 100 ml; (iii) between 0.05 and 3 wt. % of 5 thickener, based on total weight of the composition. The thickener is preferably selected from the group consisting of cellulose, xanthan gum, gellan gum, alginate, guar gum, locust bean gum, gum karaya, gum tragacanth, carrageenan, and mixtures thereof. The composition preferably has a loss factor tan δ between 0.1 and 100, as measured at any strain in the range of 1 100% at 0.1 Hz and 20° C. It is particularly found that a thickener selected from the group consisting of gellan gum, xanthan gum and cellulose greatly reduces sedimentation.

The present invention relates to a fermented beverage, and provides a multi-bacteria fermented Chinese yam beverage and a preparation method thereof against the present situation that the existing fermented yam beverage has long production cycle and poor stability and taste. The beverage is made from the following ingredients: Chinese yam, skim milk powder, white sugar, citric acid, sodium citrate, carboxymethylcellulose sodium, pectin, xanthan gum, gellan gum, 2,3-Dihydroxypropyl octadecanoate, sucrose ester, sodium tripolyphosphate, nisin, ethyl maltol, beer yeast and lactobacillus plantarum. The beverage has a unique flavor and a high nutritional value.

The invention discloses a gellan gum composition, which is mainly prepared from a gellan gum with a high acetylation degree and/or a gellan gum with a low acetylation degree or a derivative thereof. The invention also provides a preparation method of the composition and a use method of the composition. The composition has a large amount of application serving as an injection device and/or implanted device and a medicament releasing system. The composition has the advantages that: by controlling the gelling temperature and gel elasticity of the composition, the composition can be injected in asolution state when injected to beatify so as to reduce the injection pushing resistance, and then is changed into a cohesive gel to play the corresponding role; and when prepared into a water-solublemedicinal gel, the composition can be easily and uniformly mixed by stirring in a solution state to form a gel, thereby reducing the difficulty of uniformly mixing the gel.

The present invention relates to a protein silk preparation method and applications of protein silk as a cosmetic additive in the field of cosmetics. According to the present invention, natural polymer materials are adopted as a carrier and a film forming material to wrap natural silk protein hydrolysate-silk peptide to prepare a silk-like product, and the silk-like product is added to various transparent cosmetics so as to increase beautifying effects, wherein the natural polymer materials adopted as the carrier and the film forming material are sodium alginate, gellan gum, carrageenan and locust bean gum, the transparent cosmetics comprise two classes, one class is an essence and gel system adopted carbomer as a suspending agent, the essence and gel system comprises an essence liquid, an essence original liquid, a massage cream, a jelly mask and the like, the other class is a surfactant system adopted SF-1 as a suspending agent, and the surfactant system comprises a transparent facial cleanser, a transparent shower gel, a transparent shampoo and the like.

The invention discloses a curcumin microemulsion ion sensitive in situ gel preparation for intranasal administration, which uses curcumin as a raw medicine and adopts a surfactant, a cosurfactant, an oil phase and a gellan gum solution. According to the portions by weight, the preparation comprises 0.5-8 portions of curcumin, 4-25.6 portions of oil phase, 17-46.4 portions of surfactant, 17-46.4 portions of cosurfactant and 20-50 portions of gellan gum solution, wherein the mass concentration of the gellan gum solution is 0.1%-1.0%. The preparation method comprises the following steps of: firstly, uniformly mixing the oil phase, the surfactant and the cosurfactant in a mode of electromagnetic stirring, vortex oscillation or ultrasound; secondly, adding the curcumin, and fully stirring the mixture to be dissolved; thirdly, dropwise adding the gellan gum solution; and finally, continuously stirring the mixture to obtain the curcumin microemulsion ion sensitive in situ gel preparation for intranasal administration. After intranasal administration of the microemulsion ion sensitive in situ gel preparation disclosed by the invention, the medicine can reach brain targeted sites through a direct nose-brain path and a systemic circulation path, so that the curcumin has a treatment effect on brain tissues.

The invention relates to a plant protein empty capsule and a preparation method thereof. The plant protein empty capsule is prepared from the following raw materials in percentage by mass: 73.7% of hydroxypropyl methyl cellulose (HPMC), 8% of pharmaceutical-grade polyvinylpyrrolidone (PVP), 1% of pharmaceutical-grade 1788 polyvinyl alcohol (PVA), 2.5% of glycerol, 2.5% of polyethylene glycol (PEG), 3% of titanium dioxide, 0.3% of water soluble pigment, 6% of gellan gum, 2% of calcium chloride and 1% of a surfactant which is lauryl sodium sulfate. The preparation method of the plant protein empty capsule comprises the following steps: forming a layer of hard shell blending polymer on an axial needle, demoulding and trimming to prepare a capsule shell.