The invention discloses an intelligent indoor cleaning device with air purification and disinfection functions. The device comprises a device body, a cleaning system, a mopping system, a fumigation system, a diffusion system, an intelligent controller and a charging battery. The device body is provided with a roller on the bottom surface and an ultrasonic sensor in the front portion. The cleaningsystem includes side brushes, a cleaning brush, a dust suction opening, a dust collector and a dust box. The mopping system includes a mopping rod and a mopping mechanism. The fumigation system includes a medicine liquid cartridge for accommodating a sterilizing liquid, an atomizer, and an atomizing nozzle. The diffusion system includes a fan, ventilation openings and ventilation pipes. The intelligent controller includes a control terminal and a motor connected to the control terminal, the control terminal is connected to the ultrasonic sensor, and the motor drives the motions of the roller,a brush rod, the cleaning brush, the dust collector, the mopping rod, a guide roller, a rotating shaft, the atomizer and the fan respectively. The charging battery provides power for the intelligent controller. The device achieves an integrated set of ground cleaning and sterilization, not only meets the family's cleaning requirements, but also achieves the purpose of purifying air, and ensures the health and safety of a family's living environment.