The invention discloses an automatic production line of freeze-dried products. The automatic production line comprises a control system, a sterile isolator, a conveying mesh belt, a bottle washing system, a filling system, a freeze-drying system and a capping system, wherein the bottle washing system, the filling system, the freeze-drying system and the capping system are sequentially arranged inthe conveying direction of the conveying mesh belt, the conveying mesh belt, the filling system, the freeze-drying system and the capping system are all arranged in the sterile isolator, the conveyingmesh belt comprises a feeding transportation assembly and a discharging transportation assembly, the freeze-drying system comprises a freeze-drying cabinet, a feed front push device and a discharge rear push device, and the control system is correspondingly connected with the sterile isolator, the bottle washing system, the filling system, the freeze-drying system, the capping system and the conveying mesh belt. According to the automatic production line of the freeze-dried products, the aseptic requirement is met, automatic feeding and discharging of the freeze-drying cabinet can be realizedcontinuously and stably, feeding and discharging of the freeze-dried products are independent, discharging can be carried out while feeding is carried out, the structure is simple, and use is convenient.