The invention relates to the technical field of coatings, in particular to an energy-storage luminous negative-ion water-based interior wall coating. The coating comprises the following components: negative ion powder, luminous powder, a film forming agent, deionized water, a dispersing agent, a thickening agent, a defoaming agent, a preservative, an antifreezing agent, titanium dioxide, calcium carbonate, talcum powder and bentonite. The preparation method comprises the following steps: firstly, adding the film forming agent, deionized water and the dispersing agent into a stirring kettle, and carrying out stirring; then, adding the thickening agent, and carrying out stirring; when the thickening agent is completely dissolved, sequentially adding the negative ion powder, the luminescent powder, titanium dioxide, calcium carbonate, talcum powder and bentonite, and carrying out stirring at a high speed; and finally, adding the defoaming agent, the preservative and the antifreezing agent, carrying out stirring at a high speed, and then carrying out stirring at a low speed to complete preparation of the coating. According to the energy-storage luminous negative-ion water-based interior wall coating and the preparation method thereof, the coating has the functions of energy storage luminescence and negative ion release, and can achieve composite effects of illumination, energy conservation and air purification.