The invention discloses reliving cream which comprises the following components in percentage by weight: 3.1-16% of effective components, 1.6-5% of an emulsifier, 9-20% of grease, 3-10% of a silk extract, 0.5-3% of Carbomer, 0.5-3% of triethanolamine, 1-5% of propylene glycol, 3-5% of 1,2-pentanediol and the balance of deionized water, wherein the effective components comprise a centella asiaticaextract, lactoferrin, a saccharomyces lysate extract and ceramide-3. The invention further discloses a preparation method of the reliving cream. The reliving cream is prepared from the silk extract which is compounded with the centella asiatica extract, the lactoferrin, the saccharomyces lysate extract and the ceramide-3, under coactions of the emulsifier, a moistening agent, a thickening agent, the grease, a pH value adjusting agent and a preservative, synergetic effects of the raw materials are taken into play, high external quality of the made cream can be maintained, remarkable relieving and itching quenching functions can be achieved, the sensitization rate can be reduced, and the relieving cream has the advantages of being gentle and non-irritant, high in moistening degree, good in skin feeling, easy to absorb, safe and free of toxic or side effect, and the like.