To provide a topical pharmaceutical composition containing
diclofenac in which
crystal precipitation is suppressed. [Solution] A topical pharmaceutical composition comprising (A) one or more selected from the group consisting of
loxoprofen, its salts and hydrates thereof, (B) one or more selected from the group consisting of
diclofenac, its salts and hydrates thereof, and (C) a lower
alcohol, wherein the content of the lower
alcohol of (C) is 35% by
mass or more and 60% by
mass or less based on the total
mass of the topical pharmaceutical composition, and the pH of the topical pharmaceutical composition is 5.0 to 7.5.