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22 results about "Lost appetite" patented technology

Pure traditional Chinese medicine preparation for treating depression and preparation method thereof

The invention belongs to the field of traditional Chinese medicine preparations, and provides a pure traditional Chinese medicine preparation for treating depression and a preparation method of the pure traditional Chinese medicine preparation. The preparation method comprises the following steps: S1, weighing raw materials according to a formula, putting the raw materials into a clean container, adding water which is 8-12 times of the total weight of the raw materials, and soaking at room temperature for 1-2 hours; s2, transferring the soaked raw materials and liquid medicine into a decoction container, boiling with strong fire, then turning into slow fire, and decocting for 1.5-2.5 hours in a slightly boiling state; according to the pure traditional Chinese medicine preparation disclosed by the invention, through reasonable compatibility of various traditional Chinese medicinal materials, all the components have a synergistic effect, and the effects of soothing liver and regulating qi, strengthening spleen and harmonizing stomach, nourishing heart and tranquilizing mind, promoting blood circulation to remove blood stasis, reducing phlegm and clearing damp are jointly achieved; the pure traditional Chinese medicine preparation can effectively improve the symptoms of low mood, restless mood, insomnia and dreaminess, inappetence and hypodynamia of depression patients, and clinical practice verifies that the pure traditional Chinese medicine preparation prepared by the invention has a remarkable effect in the aspect of treating depression compared with existing conventional anti-depression western medicines.
Owner:袁高峰

Fatty acid analogs and their use in treatment of cognitive impairment, behavioral conditions and chronic pain

PendingJP2025172099ANervous disorderMetabolism disorderConvulsionOpiate addiction
To provide compositions and methods for treating and preventing cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, and addiction.SOLUTION: Also provided are methods for the diagnosis and monitoring of cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, addiction, and other conditions such as convulsion or seizure. These compositions comprise fatty acid compounds and salts thereof which may be administered either alone, in combination with other medicaments, or as part of various treatment regimens. The provided compositions are effective for modulating markers, including, but not limited to, behavior associated with cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, opiate addiction, and other related conditions. Methods for administering the compositions are also provided.SELECTED DRAWING: Figure 1
Owner:EPITRACKER INC

A traditional Chinese medicine composition for treating anorexia in children and application thereof

The present application relates to a kind of traditional Chinese medicine composition for treating pediatric anorexia, the traditional Chinese medicine composition is made of the following weight parts of raw medicinal materials: 7-11 parts of Taizishen, 7-11 parts of Cangzhu, 7-11 parts of Fuling, 7-11 parts of Huoxiang, 7-11 parts of Gegen, 7-11 parts of Qingpi, 6-13 parts of Laiqiezi, 4-8 parts of Lianqiao, 7-11 parts of Sanleng, 7-11 parts of Shanzha.The present application also provides the use of traditional Chinese medicine composition for pediatric anorexia.The present application uses several drugs together, which is integrated with invigorating spleen, transporting spleen and activating spleen, so that the spleen is healthy, the spleen and stomach qi movement is appropriate, and the human body qi movement is adjusted, so that the whole body qi movement is operated, the qi movement is operated, the five internal organs are harmonious, and the whole prescription plays the effect of invigorating spleen and transporting.The total effective rate and the improvement of TCM syndrome score of the traditional Chinese medicine composition of the present application are better than those of the control group, especially in improving the symptoms of anorexia, reduced food intake and other symptoms such as salivation, belching, hiccups, nausea and other symptoms.
Owner:SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition for treating diarrhea and application thereof

The application provides a traditional Chinese medicine composition for treating diarrhea, and relates to the technical field of traditional Chinese medicine pharmacy. The application provides a traditional Chinese medicine composition for treating chronic diarrhea, which is prepared from madder, yuyulang, camphor tree bark, white peony root, jujube, licorice, lily, trichosanthes root and heron herb. The drugs are used together to have the functions of tonifying the spleen and stomach, astringing the lung to stop diarrhea and warming the middle and promoting qi. The traditional Chinese medicine composition can effectively relieve and improve the clinical symptoms of patients with chronic diarrhea, such as diarrhea, loss of appetite, lassitude and fatigue, and has a remarkable curative effect, so it is worthy of further clinical promotion and application.
Owner:HENAN RUNHONG HERBAL PHARMA

Spleen-tonifying and kidney-tonifying herbal tea formula and use method thereof

The invention relates to the technical field of health-care herbal tea, in particular to a formula and a using method of spleen-tonifying and kidney-tonifying herbal tea. The traditional Chinese medicine is prepared from the following raw materials by weight: 6-11g of radix pseudostellariae, 6-11g of rhizoma atractylodis macrocephalae, 6-11g of poria cocos, 3-6g of liquorice, 6-10g of ginger processed pinellia, 6-11g of pericarpium citri reticulatae, 9-13g of angelica sinensis, 6-10g of rehmannia, 6-11g of polygala tenuifolia, 6-13g of fructus alpiniae oxyphyllae, 11-16g of tortoise plastron, 6-13g of rhizoma drynariae, 9-14g of vinegar turtle shell, 10-16g of rhizoma cibotii, 9-13g of dipsacus root, 6-13g of dendrobe, 9-16g of sanguisorba officinalis and 6-11g of rhizoma cimicifugae. Liujunzi decoction is matched with radix angelicae sinensis and radix rehmanniae to construct a qi-blood tonifying basis, and cooperates with tortoise plastron, vinegar turtle shell and rhizoma drynariae to fill kidney essence and strengthen tendons and bones, meanwhile, the rhizoma cimicifugae is combined to enhance the qi lifting effect of ginseng, and symptoms of inappetence, abdominal distension and sticky stool caused by spleen deficiency and dampness stagnation and soreness and weakness of waist and knees and weakness of limbs caused by kidney deficiency and bone weakness are synchronously improved.
Owner:王韶焓

Depression relieving and liver soothing pill and preparation method thereof

The invention discloses a depression-relieving and liver-soothing pill and a preparation method thereof, and belongs to the technical field of Chinese patent medicines. The depression-relieving and liver-soothing pill comprises the following active ingredients: vinegar-processed rhizoma cyperi, grape seeds, bran-fried rhizoma atractylodis macrocephalae, poria cocos, hawthorn, pericarpium citri reticulatae, ginger-fried fructus gardeniae, vinegar-processed rhizoma corydalis, fructus aurantii, betel nuts, liquorice, medicated leaven, pericarpium citri reticulatae viride, radix aucklandiae, fructus amomi and radix linderae. According to the invention, the alcohol extract of the grape seeds is added into the traditional depression-relieving and liver-soothing pill, so that the depression-relieving and liver-soothing pill is obviously improved in the effect of enhancing the activity of pepsin and pancreatin, and a better instant curative effect can be obtained when the depression-relieving and liver-soothing pill is used for treating chest and hypochondrium fullness, inappetence and other symptoms.
Owner:CIXI MATERNAL & CHILD HEALTH HOSPITAL

Traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and irritable bowel syndrome

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and IBS (irritable bowel syndrome). The composition comprises radix pseudostellariae, poria cocos, raw coix seeds, fingered citron, polygala tenuifolia, roasted rhizoma atractylodis macrocephalae, lotus seed pulp, mint, roses, lilies, raw fructus gardeniae, fermented soybeans and raw hawthorn fruits. Liver soothing, depression relieving, spleen strengthening and heart nourishing are taken as core treatment rules, heat clearing, restlessness relieving, digestion promoting and stagnation removing are also taken, and the complex pathogenesis that the two are causal to each other is formed for gastrointestinal dysfunction caused by emotional discomfort. The formula is characterized in that the three internal organs of the heart, the liver and the spleen are treated at the same time, the four methods of tonifying, dredging, clearing and eliminating are used at the same time, balance is achieved between qi regulating and healthy qi supporting, and the formula is suitable for patients suffering from complex heart and body diseases with low mood, anxiety, dysphoria, insomnia, amnesia, abdominal fullness, inappetence, loose stool or loose stagnation.
Owner:FIRST AFFILIATED HOSPITAL OF LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE

ghrelin secretion promoters

ActiveCN115918726BMilk preparationBacteriaSide effectLost appetite
The present invention aims to provide a novel ghrelin secretion enhancer that is easily accessible and easy to consume, can stimulate the secretion of ghrelin present in the human body, and is safe and has no side effects. By ingesting specific lactic acid bacteria themselves or fermented milk produced using them as a ghrelin secretion enhancer, poor appetite can be significantly alleviated in an easily accessible, easy, and safe manner.
Owner:MEIJI CO LTD

Construction method and application of zebra fish inappetence model

The invention discloses a construction method and application of a zebra fish inappetence model, and belongs to the field of medicine and health food evaluation. According to the method, a zebra fish inappetence model is constructed, the water temperature, the light-dark alternating rhythm, the conductivity and the illumination intensity are adjusted, the appetite and normal growth and development of zebra fish are synergistically inhibited, the scheme is easy to operate, other interference factors are few, the result is more accurate, and the requirement for appetite promotion efficacy evaluation in the fields of food, health care products, medicines and the like can be met.
Owner:NANJING AURORA BOREALIS QUALITY INSPECTION TECH SERVICE CO LTD

Health-care anthelmintic traditional Chinese medicine composition and preparation method thereof

PendingCN122643395ACnidium monnieriOfficinal
This invention discloses a traditional Chinese medicine composition for health maintenance and deworming, and its preparation method, comprising the following raw materials in parts by weight: 12-18 parts of Artemisia annua, 8-15 parts of Rhizoma Scutellariae, 10-18 parts of Fructus Cnidii, 12-18 parts of Folium Platycladi, 8-15 parts of Radix Stemonae, 15-25 parts of Radix Smilax, 6-12 parts of Radix Sophorae Flavescentis, 10-15 parts of Cortex Dictamni, and 5-15 parts of pharmaceutical excipients, wherein the pharmaceutical excipients include soluble starch or dextrin. This invention relates to traditional Chinese medicine compositions. In the field of compound technology, this invention uses Artemisia annua as the principal drug to kill parasites and clear heat; Stemona japonica, Cnidium monnieri, and Sophora flavescens as assistant drugs to dry dampness, kill parasites, and relieve itching; Rhizoma Scutellariae, Fructus Platycladi, and Cortex Dictamni as adjuvant drugs to clear heat, detoxify, and have antibacterial and anti-inflammatory effects; and Smilax china to promote blood circulation, remove blood stasis, and have anti-inflammatory effects. The components work together to directly kill or inhibit internal and external parasites, while clearing away damp-heat toxins caused by parasite metabolism and improving accompanying symptoms such as skin itching, fatigue, and loss of appetite.
Owner:QINGDAO ZESHENG MEDICAL MANAGEMENT CO LTD

Traditional Chinese medicine composition with kidney tonifying and bowel relaxing functions as well as preparation method, preparation and application of traditional Chinese medicine composition

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with kidney tonifying and bowel relaxing functions and a preparation method, a preparation and application thereof. The traditional Chinese medicine composition comprises the following components: wine-processed cistanche, angelica sinensis, cooked rhubarb, semen cassiae, achyranthes bidentata, radix paeoniae alba, pericarpium citri reticulatae, rhizoma alismatis, fructus aurantii and rhizoma cimicifugae. The traditional Chinese medicine composition provided by the invention is mainly used for warming the kidney, boosting essence and relaxing bowel. The traditional Chinese medicine is used for treating dry stool, constipation due to intestinal dryness, clear and long urine, soreness and weakness of waist and knees, general weakness, stomachache, abdominal distension, blood deficiency and sallow yellowness, insomnia, headache and dizziness, spontaneous perspiration and inappetence caused by kidney deficiency and body fluid deficiency; the traditional Chinese medicine is used for treating irritable bowel syndrome and menstrual disorder.
Owner:CHANGCHUN SIXTH HOSPITAL (CHANGCHUN MENTAL HOSPITAL CHANGCHUN MENTAL HEALTH INSTITUTE CHANGCHUN NURSING HOSPITAL)

A mosla herb composition for removing dampness, invigorating spleen, refreshing brain and tranquilizing mind, a preparation method and application thereof

PendingCN122139947ANervous disorderDigestive systemLost appetiteFood technology
The application provides a patchouli composition for removing dampness, invigorating the spleen, refreshing the brain and calming the nerves and a preparation method and application thereof, and belongs to the technical field of functional food. The composition comprises the following raw materials: patchouli, 10-20 parts; tuckahoe, 8-18 parts; bergamot, 5-15 parts; dried tangerine or orange peel, 3-10 parts; and fried licorice, 2-6 parts. The application takes five kinds of food-medicine homologous materials, namely, patchouli, tuckahoe, bergamot, dried tangerine or orange peel and fried licorice, as core effective components, realizes the synergistic effects of removing dampness and turbidity, invigorating the spleen and stomach, soothing the liver and regulating qi, refreshing the brain and calming the nerves through scientific proportioning, and can be prepared into various edible dosage forms such as granules, oral liquid and ointment, and is especially suitable for modern sub-healthy people with heavy dampness, weak spleen and stomach, emotional irritability, dizziness, poor appetite and heavy limbs, is mild and safe, has no side effects, is suitable for long-term conditioning, and belongs to the technical field of functional conditioning food with food-medicine homology.
Owner:XINGYUAN TIMES (GUANGZHOU) BIOTECHNOLOGY CO LTD

Methods of preventing and / or treating side effects associated with anti-cancer agents using non-naturally occurring melanocortin analogs and anti-GDF-15 antibodies

Provided herein are compositions comprising a non-naturally occurring melanocortin analogue in combination with a spiro compound and / or an antibody or antigen-binding fragment thereof. The composition may further include an anti-cancer agent (e.g., a chemotherapeutic agent). Also provided herein are pharmaceutical compositions incorporating the compositions; methods of using the compositions to modulate weight, including but not limited to increasing appetite, preventing inappetence, promoting weight gain, preventing weight loss, and / or treating, preventing, or otherwise reducing cachexia and / or anorexia in a subject in need thereof.
Owner:ENDWIKA BIOTECH LTD

A medicinal ointment for treating qi deficiency and blood stasis syndrome and its preparation method

This invention discloses a medicinal ointment for treating Qi deficiency and blood stasis syndrome and its preparation method. The raw materials of the medicinal ointment include: ginseng, atractylodes macrocephala, astragalus membranaceus, rehmannia glutinosa, dandelion, chuanxiong rhizome, costus root, turmeric, salvia miltiorrhiza, peucedanum praeruptorum, apricot kernel, sparganium rhizome, scutellaria barbata, oldenlandia diffusa, licorice, and gelatinous medicinal materials. The preparation method involves decocting the medicinal formula and then adding gelatinous materials to form the ointment. This invention improves the loss of appetite and fatigue in mice with non-small cell lung cancer syndrome caused by Qi deficiency and blood stasis syndrome by modifying the traditional Chinese medicine formula and preparing it as an ointment. It reduces whole blood and plasma viscosity by tonifying Qi, activating blood circulation, and removing blood stasis, thus promoting blood flow without damaging hepatocytes and reducing the toxic side effects of the formula on the liver. Furthermore, the ointment preparation makes it convenient for patients to carry and take.
Owner:RUIKANG HOSPITAL OF GUANGXI UNIV OF TRADITIONAL CHINESE MEDICINE (GUANGXI INTEGRATED HOSPITAL OF TRADITIONAL CHINESE & WESTERN MEDICINE)

Pharmaceutical composition for ameliorating, preventing, and treating anorexia and weight loss comprising bupleuri radix extract

PCT designated stageWO2026134901A1Organic active ingredientsDigestive systemSerotoninAnorectic
The present invention relates to a pharmaceutical composition for preventing, ameliorating, or treating anorexia and weight loss, comprising a Bupleuri Radix extract. Specifically, the present invention provides a pharmaceutical composition having effects in preventing, ameliorating, or treating anorexia and weight loss, wherein a Bupleuri Radix extract increases ghrilin, which is a hormone that stimulates appetite, and decreases TPH1(I), which is a serotonin synthase. In addition, a health functional food for preventing or ameliorating anorexia and weight loss, comprising a Bupleuri Radix extract, can be developed, and the extract can be effectively used for the treatment and the development of therapeutic agents for anorexia induced by chemotherapy in the future.
Owner:UNIVERSITY INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY

Food bowl kit

The present disclosure relates to a kit comprising: (i) a first part comprising a food bowl assembly including a first bowl having side walls and a base; a second feeding bowl disposed within the first bowl, the second feeding bowl having side walls and a solid base, the inner surface of said side walls and solid base being a closed surface; a separating module adapted to hold an olfactive product, the separating module being arranged to fit between the solid base of the second feeding bowl and the first bowl, and a vent arranged to allow odours from the separating module to exit the food bowl assembly between the first bowl and the side walls of the second feeding bowl so that odours do not pass through the second feeding bowl; and (ii) a second part comprising of a container comprising at least one olfactive product. A second aspect of the present disclosure relates to a kit as defined above for use in a method for to treat olfaction dysfunction, appetite loss or food aversion due to a disease or for treating and / or preventing a disease or disorder in an animal.
Owner:MARS INC

Blood replenishing composition for promoting utilization of iron agent

The invention discloses a blood-enriching composition for promoting utilization of an iron agent, which belongs to the technical field of health-care food, and is prepared from the following raw materials in parts by weight: 0.5-3 parts of black ginseng, 9-15 parts of astragalus membranaceus, 0.2-1 part of donkey-hide gelatin, 6-12 parts of hawthorn, 4-9 parts of jujube, 0.5-3 parts of double-petal red rose and a nutrient supplement. The nutrition enhancer at least comprises 0.05-0.5 part of an iron agent. According to the blood replenishing composition for promoting utilization of the iron agent provided by the invention, the black ginseng not only can alleviate the warm property of the astragalus membranaceus and enhance the qi tonifying ability of the astragalus membranaceus, but also can cooperate with the colla corii asini and the Chinese dates to nourish blood to carry qi, so that the situation that blood is not replenished due to deficiency of blood caused by independent blood replenishing is avoided. The black ginseng, the hawthorn and the double-petal red rose can promote blood circulation to remove blood stasis, promote transportation and transformation of the spleen and the stomach, prevent the donkey-hide gelatin and the Chinese dates from being greasy and obstructing the stomach, and are suitable for people with deficiency of qi and blood such as pale complexion, dizziness, weakness, palpitation, shortness of breath and inappetence caused by deficiency of qi and blood.
Owner:SHANDONG HONGJITANG TRADITIONAL CHINESE MEDICINE RESEARCH INSTITUTE CO LTD +1

A traditional Chinese medicine composition for preventing and / or treating porcine reproductive and respiratory syndrome, a preparation method thereof, and a traditional Chinese medicine preparation

This invention relates to the field of veterinary preventive and therapeutic drugs. The invention provides a traditional Chinese medicine composition for the prevention and / or treatment of porcine reproductive and respiratory syndrome (PRRS) and its preparation method, comprising the following components: Indigo naturalis, Forsythia suspensa, Arctium lappa, Dryopteris crassirhizoma, Lithospermum erythrorhizon, Taraxacum mongolicum, Rheum palmatum, Scutellaria barbata, Glycyrrhiza uralensis, Hordeum vulgare, Bupleurum chinense, and Terminalia chebula. The invention also provides a traditional Chinese medicine preparation comprising the aforementioned composition. Using the above-mentioned components in combination with the technical solution of this invention can effectively enhance the inhibitory effect on pathogenic microorganisms and the anti-PRRSV virus effect, improve immunity, and enhance the disease resistance of pigs; alleviate symptoms such as depression and loss of appetite caused by PRRSV, and regulate the gastrointestinal health of animals; at the same time, it has few toxic side effects and is less likely to induce drug resistance.
Owner:YUNNAN AGRICULTURAL UNIVERSITY

Processing method and application of digestion-aiding tea bag

InactiveCN120660776ATea substituesDigestionGastric pepsin
The invention belongs to the technical field of health-care food, and particularly relates to a processing method and application of a digestion-aiding tea bag. The digestion-aiding tea bag is prepared from the following raw materials in parts by weight: 25 to 35 parts of fructus crataegi, 15 to 25 parts of pericarpium citri reticulatae, 10 to 20 parts of poria cocos, 5 to 15 parts of liquorice root, 10 to 20 parts of medicated leaven and 10 to 20 parts of fructus hordei germinatus. The prepared tea bag can significantly improve pepsin activity, shorten gastric emptying time and improve symptoms such as postprandial abdominal distension and inappetence, and is especially suitable for high-fat diet people and functional dyspepsia patients.
Owner:GUANGZHOU RUNZHIYUAN HEALTH IND CO LTD

A tumor auxiliary nutritional preparation based on five grain worm oil and a preparation method and application thereof

This invention discloses a tumor adjuvant nutritional preparation based on *Pterocarya stenoptera* oil, its preparation method, and its application. The active ingredients of this preparation are composed of *Pterocarya stenoptera* oil, ω-3 fatty acids, and arginine in a mass ratio of (1-3):(1-2):(1-2), preferably 2:1:1. The preparation method includes mixing the above components evenly, followed by high-pressure homogenization and aseptic emulsification to produce an oral liquid, enteral nutrition emulsion, or powder. This preparation can effectively improve chemotherapy-induced bone marrow suppression, significantly increase white blood cell, red blood cell, and hemoglobin levels, enhance serum superoxide dismutase activity, reduce oxidative stress damage, and significantly alleviate gastrointestinal adverse reactions such as nausea, vomiting, and loss of appetite in cancer patients undergoing radiotherapy and chemotherapy, improving patients' nutritional status and quality of life, and exhibiting good safety.
Owner:JINHUA HERUI LIFE HEALTH TECHNOLOGY CO LTD

Rhizoma coptidis, radix bupleuri and radix scutellariae soluble powder for preventing and treating chicken wind-heat affecting lung syndrome and application thereof

The invention discloses a coptis chinensis-radix scutellariae soluble powder for preventing and treating a chicken wind-heat affecting lung syndrome and application thereof. According to the technical scheme, the lianhua-radix scutellariae soluble powder is administrated to sick chickens in a drinking water administration mode, 1-4 g, preferably 2 g, of the lianhua-radix scutellariae soluble powder is added to each liter of drinking water, and the lianhua-radix scutellariae soluble powder is continuously administrated for 5 days and is administrated once a day. The medicine is used for treating the chicken wind-heat invading lung syndrome caused by infectious bronchitis virus infection, and clinical symptoms comprise depressed spirit, body temperature rise exceeding 41.5 DEG C, cough and sneezing, runny nose and tracheal rale, inappetence and drinking water increase and the like. The Maxingshigan granule has the beneficial effects that when 2g of the Maxingshigan granule is added into each liter of drinking water, the total effective rate reaches 90.00% and the cure rate is 66.67% after the Maxingshigan granule is treated for 5 days, and the Maxingshigan granule is obviously superior to the 76.67% total effective rate and the 43.33% cure rate of the existing Maxingshigan granule; by increasing the content of CD3 +, CD3 + CD4 + and CD3 + CD8 + T lymphocytes in peripheral blood of the sick chicken, the immune function of the body is enhanced; the drug administration is convenient, and the method is suitable for large-scale breeding application.
Owner:XUZHOU TIANYI ANIMAL PHARMA

Traditional Chinese medicine composition for treating gastroesophageal reflux

InactiveCN120884667ADigestive systemPlant ingredientsWolfiporia cocosHeartburn
The invention discloses a traditional Chinese medicine composition for treating gastroesophageal reflux. The invention belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from rhizoma bletillae, bulbus fritillariae thunbergii, cuttlebone, calcined concha arcae, fructus amomi and the like. The traditional Chinese medicine composition has the effects of relieving hyperacidity and pain, and regulating qi and harmonizing stomach. The traditional Chinese medicine composition disclosed by the invention has an excellent clinical effect in treating the gastroesophageal reflux disease, is mild in medicine property of the whole formula, is suitable for various syndromes of the gastroesophageal reflux disease, and is particularly suitable for patients with heartburn, sour regurgitation and belching, chest distress, inappetence, vomiting, throat discomfort, light red tongue, white fur and slippery pulse caused by phlegm-heat and qi stagnation.
Owner:WANGJING HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI