The invention discloses an automatic-batching mixing granulation system. The automatic-batching mixing granulation system comprises a vacuum loading machine, a buffer storage bin, a metering unit, a metering bin, a mixing granulator and a controller. According to the automatic-batching mixing granulation system, the loading, metering, mixing and granulation operations are organically integrated, so that the seamless joint of all procedures is realized, the operation procedure is simplified, the dust pollution is avoided, and the labor intensity of operators is reduced; and furthermore, the operators do not need to specifically meter the materials, and the mixing granulation and the loading are synchronously carried out, so that the granulation period is shortened, and the production efficiency is improved.