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59results about How to "Embedding" patented technology

Manufacturing method for thin coreless substrate

The invention discloses a manufacturing method for a thin coreless substrate. The method comprises the steps of a, sequentially stacking first copper foil, first prepreg and second copper foil for conducting pressing fit for the first time to obtain a first substrate, and manufacturing a second circuit on the second copper foil, wherein the second circuit comprises a first bonding pad, and the first bonding pad extends towards the periphery to form an electroplating frame; b, on the premise that the electroplating frame is exposed, sequentially stacking second prepreg and third copper foil on the second copper foil for conducting pressing fit for the second time to obtain a second substrate, and manufacturing a first circuit and a third circuit respectively so as to obtain a substrate workblank; c, conducting pressing fit for the third time; d, forming a first blind hole and a second blind hole, and filling the first blind hole and the second blind hole by the adoption of the electroplating hole filling technology respectively to obtain a substrate model. The thin coreless substrate is manufactured through the manufacturing method, is a three-layer coreless substrate, has the symmetric pressing-fit condition and the pressing-fit structure, and achieves internal layer circuit embedment.
Owner:NAT CENT FOR ADVANCED PACKAGING

Combined foaming polylactic acid heat-resistant flame-retardant modified material and preparation method of product

The invention relates to a combined foaming polylactic acid heat-resistant flame-retardant modified material and a preparation method of a product, and belongs to the technical field of biodegradablefoaming materials. The preparation method comprises the following steps: weighing a flame retardant, a chain extender, a peroxide, a fatty acid amide compound refined from natural vegetable oil, a modifier, a degradable auxiliary material, polylactic resin and a nucleating agent in parts by weight; mixing the raw materials in a mixer according to the formula; melting, reacting and extruding the mixture in a twin-screw extruder at 160-210 DEG C to obtain polylactic acid flame-retardant modified masterbatch. The obtained polylactic acid flame-retardant modified masterbatch and a compound chemical foaming agent can be further mixed through various plastic processing modes, then a compound physical foaming agent is injected, and in cooperation with a supercritical fluid foaming agent conveyingdevice, the mixture is processed into the product in a large-scale mode. According to the technology, the foaming rate can be increased, the comprehensive performance of the foaming material is effectively improved, and the prepared foaming material and product have low apparent density and are widely applied to the fields of heat insulation, buffering and packaging.
Owner:广州绿徽新材料研究院有限公司

Automatic nut burying and sprue cutting equipment

The invention belongs to the technical field of machines, and provides automatic nut burying and sprue cutting equipment which solves the problem that an existing pipe clamp is low nut burying and sprue cutting efficiency. The automatic nut burying and sprue cutting equipment is characterized in that a first driving source on a first workbench can drive a sliding rack to move; locating columns are arranged on the sliding rack in a spaced manner; the feed end of a conveying passage is connected with a vibrating material disc; the discharge end of the conveying passage is located at the locating columns; a manipulator is fixedly connected with a mounting plate; first clamping cylinders are arranged on one side of the mounting plate; clamping air nozzles are formed in the other side of the mounting plate; a second driving source and a sliding plate are arranged on a second workbench; the second driving source can drive the sliding plate to move; a locating rack is arranged on the sliding plate; a mounting rack is arranged on the second workbench; lifting air cylinders are arranged on the mounting rack; piston rods of the lifting air cylinders are fixedly connected with a first pressing plate; and the first pressing plate is fixedly connected with cutters. The automatic nut burying and sprue cutting equipment has the advantage of improving the production efficiency of a pipe clamp.
Owner:YONGGAO CO LTD

Chia seed oil microcapsules and preparation method thereof

The invention discloses a chia seed oil microcapsule and a preparation method thereof, and belongs to the technical field of health food processing, the core material of the microcapsule comprises chia seed oil, and the wall material comprises whey protein isolate and tremella polysaccharide; the preparation method comprises the following steps: preparing a thermal denatured whey protein isolate solution; preparing tremella polysaccharide; dissolving tremella polysaccharide in water, adding a thermal denatured whey protein isolate solution into the obtained tremella polysaccharide solution, then adding chia seed oil into the obtained mixed solution, and homogenizing to obtain an emulsion; and carrying out spray drying to obtain the chia seed oil microcapsule. The chia seed oil microcapsule is high in chia seed oil embedding rate, excellent in quality, high in oxidation resistance, good in stability and not prone to oxidative deterioration, so that the oxidation stability of the chia seed oil is improved, and the storage period and the shelf life of the chia seed oil are greatly prolonged.
Owner:JILIN AGRICULTURAL UNIV

Drive for Switching a Double Seat Valve

#CMT# # / CMT# The drive (70) has drive pistons (74,78) that are provided in valve housing (2). The pressure medium chambers (84,88) are provided in valve housing for creation of partial open positions. The drive piston (74) is moved from closed position to partially open position against open position, so that valve (1) is operated using one spool (3) and one seat plate (4) at one configuration of drive. The drive piston (78) is moved from closed position to partially open position toward open position, so that valve is operated using seat plate at other configuration of drive. #CMT#USE : # / CMT# Drive for shifting double seat valve. #CMT#ADVANTAGE : # / CMT# The double seat valve can be shifted reliably and safely. Installation space of the drive is reduced. #CMT#DESCRIPTION OF DRAWINGS : # / CMT# The drawing shows a sectional view of the double seat valve with drive. 1 : Valve 2 : Valve housing 3 : Spool 4 : Seat plate 70 : Drive 74,78 : Drive pistons 84,88 : Pressure medium chambers.
Owner:GEA TUCHENHAGEN GMBH

Full-soluble edible mushroom protein and preparation method thereof

The invention discloses a full-soluble edible mushroom protein and a preparation method thereof. The full-soluble edible mushroom protein is prepared by the following steps: unmodified edible mushroom protein is expanded under an alkaline condition, and then acid is added to adjust the edible mushroom protein to be neutral. According to the preparation method, the primary structure of the protein is not changed, the nutritional value of the protein can be reserved to the maximum extent, the obtained edible mushroom protein is free of exogenous additive components, the acceptance degree of consumers is improved to the maximum extent, reasonable utilization of edible mushroom byproducts is achieved, and resource waste and environmental pollution are effectively avoided.
Owner:JIANGNAN UNIV

Method for efficiently loading medicines in cell membrane microcapsules

The invention discloses a method for efficiently loading medicines in cell membrane microcapsules. The method comprises the following steps: preparing the cell membrane microcapsules by using human vascular endothelial cells as raw materials; soaking the obtained cell membrane microcapsules in a mixed solution of digitonin and medicines, wherein the digitonin is capable of increasing the cell membrane permeability, and the medicines penetrate into the cell membrane microcapsules; using calcium ions for sealing the cell membranes, thus obtaining the medicine-loading cell membrane microcapsules. The preparation method disclosed by the invention is simple, convenient, controllable, fast in speed, high in production efficiency and capable of conveniently loading the multiple medicines in the cell membrane microcapsules and adjusting the medicine-loading capacity of the cell membrane microcapsules and has good application prospect.
Owner:ZHEJIANG UNIV

Precision pulse arc spot welding ceramic particle planting method

ActiveCN111468801AAutomateReduce equipment cost investmentArc welding apparatusElectrically conductiveCeramic particle
A precision pulse arc spot welding ceramic particle planting method comprises the following steps that (1) the surface of a to-be-planted workpiece is polished, leveled and cleaned; (2) a metal conductive layer is plated on the surfaces of to-be-planted ceramic particles; (3) the workpiece is connected to a negative electrode of spot welding equipment, a tungsten electrode is connected to a positive electrode of the spot welding equipment, the surface metallized ceramic particles are uniformly arranged on the surface of the to-be-planted workpiece, precise pulse arc spot welding equipment is started, and particle planting parameters are set; (4) welding wires are introduced between the electrodes and the particles, the welding wires, the particles and the workpiece are in direction contact, a power supply is turned on when the electrodes are a certain distance away from the workpiece to form pulse arcs, and the pulse spot welding particle planting process is completed; and (5) large-area ceramic particle planting is completed in a point-by-point planting mode, so that a wear-resistant coating is formed. The method can realize large-area ceramic particle planting.
Owner:NANCHANG HANGKONG UNIVERSITY

Preparation device and method for continuous carbon fiber reinforced thermoplastic resin base prepreg sheet

The invention discloses a preparation device and method for a continuous carbon fiber reinforced thermoplastic resin base prepreg sheet. Through the cooperation of a fiber bundle filament passing unitand a carbon fiber bundle pulling roller, a carbon fiber bundle is passed into a fiber bundle embedding, cutting and splicing unit so as to be clamped; a splitting roller, a filament combing device and a second-level splitting plate in a fiber bundle splitting and tensioning unit are used for splitting the tensioned carbon fiber bundle; an annular guide rail in the fiber bundle embedding, cuttingand splicing unit drives a clip clamping the carbon fiber bundle to press downwards, and the tensioned carbon fiber bundle perpendicularly and downwards cut a molten-state resin flake and is embeddedinside, so that the carbon fiber bundle is embedded into a thermoplastic resin base and is cut off; and through the cyclic process, the continuous carbon fiber reinforced thermoplastic resin base prepreg sheet is prepared, and the problems that during the preparation process of the continuous carbon fiber reinforced thermoplastic resin base prepreg sheet, the viscosity of the resin base is high,the carbon fiber bundle is difficult to impregnate sufficiently, and the fiber content is hard to accurately control are solved.
Owner:JIANGSU UNIV

Microcapsule powder stable in gastric acid as well as preparation method and application of microcapsule powder

The invention discloses microcapsule powder stable in gastric acid as well as a preparation method and application of the microcapsule powder. The microcapsule powder comprises a core material and a capsule material coating the core material, wherein the melting point of the capsule material is more than 42 DEG C, the capsule material cannot be decomposed or dissolved under the action of protease and gastric acid, and the capsule material can be decomposed under the action of intestinal digestive enzyme. According to the microcapsule powder, the core material is coated with the capsule material, and efficient coating of the core material can be achieved through a single component; meanwhile, under the condition that conventional intragastric stability is achieved, the room-temperature open environment has excellent stability, and the problem that a conventional embedding scheme can only achieve intragastric stability, but has poor stability in the room-temperature open environment is solved.
Owner:HOBOOMLIFE BIO TECH SHENZHEN CO LTD

5-fluorouracil drug-loading microspheres and preparation method thereof

The invention relates to 5-fluorouracil drug-loading microspheres and a preparation method thereof. The invention especially relates to bio-degradable high-molecular-material-coated 5-fluorouracil drug-loading microspheres and a preparation method thereof. According to the preparation method, alpha-cyanoacrylate is adopted as a carrier, and 5-fluorouracil is embedded during an alpha-cyanoacrylate monomer polymerization process, such that drug-loading microspheres with an average particle size of 200nm-5mum are obtained, wherein the mass ratio of 5-fluorouracil to alpha-cyanoacrylate is 1 / 100-50 / 100. The invention aims at overcoming defects of existing 5-fluorouracil drug-loading microspheres and preparation methods thereof, and at providing a sustained-release preparation which can be used on surgical wounds and in epidermal administrations. With the cooperation of biological glue in surgical sutures in body cavity or on body surface, degradation speed consistency can be provided. The operation is simple. According to the invention, various other additives such as organic solvents, surfactants, and excipients are not needed.
Owner:海宁经开产业园区开发建设有限公司

Enzyme-responsive controlled-release insecticide as well as suspending agent and preparation method thereof

The invention discloses an enzyme-responsive controlled-release insecticide as well as a suspending agent and a preparation method thereof, wherein the enzyme-responsive controlled-release insecticidehas a core-shell structure, enzyme-responsive lignin-xylan nano composite microspheres are used as a wall material, and an insecticide embedded in the wall material is used as a core material; the insecticide is a hydrophobic insecticide; xylan selected by the enzyme-responsive type lignin-xylan nano composite microspheres is water-insoluble xylan, and lignin selected by the enzyme-responsive type lignin-xylan nano composite microspheres is solvent type lignin. According to the controlled-release insecticide, xylanase hydrolysis can be used for controlling release of the insecticide, controllable release of the insecticide on the surfaces of crops is achieved, the action time of the insecticide is prolonged, and the utilization rate of the insecticide is increased.
Owner:SICHUAN AGRI UNIV

5-fluorouracil drug-loading microspheres and preparation method thereof

The invention relates to 5-fluorouracil drug-loading microspheres and a preparation method thereof. The invention especially relates to bio-degradable high-molecular-material-coated 5-fluorouracil drug-loading microspheres and a preparation method thereof. According to the preparation method, alpha-cyanoacrylate is adopted as a carrier, and 5-fluorouracil is embedded during an alpha-cyanoacrylate monomer polymerization process, such that drug-loading microspheres with an average particle size of 200nm-5mum are obtained, wherein the mass ratio of 5-fluorouracil to alpha-cyanoacrylate is 1 / 100-50 / 100. The invention aims at overcoming defects of existing 5-fluorouracil drug-loading microspheres and preparation methods thereof, and at providing a sustained-release preparation which can be used on surgical wounds and in epidermal administrations. With the cooperation of biological glue in surgical sutures in body cavity or on body surface, degradation speed consistency can be provided. The operation is simple. According to the invention, various other additives such as organic solvents, surfactants, and excipients are not needed.
Owner:海宁经开产业园区开发建设有限公司

Probiotic microcapsule preparation based on water-in-water emulsion structure and preparation method thereof

The invention belongs to the field of probiotic microcapsule preparations, and particularly relates to a probiotic microcapsule preparation based on a water-in-water emulsion structure and a preparation method thereof. According to the method, a water-phase continuous phase in which a particle stabilizer is dispersed and a water-phase dispersed phase containing probiotics are subjected to shear emulsification, a stable water-in-water Pickering emulsion loaded with the probiotics is prepared, and the probiotic microcapsule preparation can be obtained after the emulsion loaded with the probiotics is dried. According to the water-in-water emulsion system constructed by the method, an oil-water interface barrier existing in a traditional oil-water emulsion system is broken through, free migration of water in the drying process after embedding of the probiotics is broken through, combination of embedding and drying of the water-in-water Pickering emulsion is achieved, and particularly, the probiotic solid preparation can be directly prepared through spray drying. According to the prepared probiotic preparation, the tolerance of probiotics is improved, and the survival rate can still reach 97% or above after the probiotic preparation is stored for six months under the normal temperature condition.
Owner:HUAZHONG AGRI UNIV

Preparation method of set-style yogurt containing acid juice

InactiveCN102919358AGood uniform physical formRich tasteMilk preparationBiotechnologyFruit juice
A preparation method of set-style yogurt containing acid juice (pH value of original juice less than or equal to 4) belongs to the technical field of food processing. The technology relates to a method which is used for preparing the set-style yogurt containing acid juice by taking fresh milk (or full-cream milk powder) and acid juice as raw materials. The preparation method comprises the following main processes: firstly mixing 3%-10% of acid juice and 0.3-0.8% of stabilizing agent into an auxiliary material a, and adding 6%-9% of white granulated sugar to 80-85% of milk liquid; mixing two feed liquids, metering the volume, sterilizing for 5-12 minutes at the temperature of 90 DEG C to 98 DEG C after heating and homogenizing, and cooling till reaching 42 DEG C to 45 DEG C for standby application; inoculating lactic acid bacteria into the prepared milk liquid containing the acid juice, filling and sealing covers; and keeping the inoculated milk liquid containing the acid juice warm at the temperature of 42 DEG C + / - 2 DEG C for 5.5 hours, and then refrigerating the milk liquid for 12-18 hours to obtain the product. The set-style yogurt prepared by the method integrates the nutrition of the acid juice and fruit juice and is unique in mouthfeel; no like products are sold on the market; and as the set-style yogurt has high added value and the production cost of the set-style yogurt is lower than that of stirred yoghurt, the set-style yogurt has a great market potential.
Owner:SICHUAN ACAD OF FOOD & FERMENTATION INDS

Oral insulin liposome hydrogel and application thereof

The invention discloses oral insulin liposome hydrogel and application thereof, and belongs to the technical field of insulin pharmacy. The oral insulin liposome hydrogel comprises an insulin-loaded liposome and a hydrogel with a core-shell structure formed by modified sodium alginate, the core is the insulin-loaded liposome, and the shell is a hydrogel framework formed by the modified sodium alginate; the insulin-loaded liposome is formed by mixing an insulin compound, phosphatidyl ethanolamine and cholesterol in an organic solvent, the particle size of the insulin-loaded liposome is 100-200 nm, and the PD I value of the insulin-loaded liposome is 0.1-0.4; the modified sodium alginate is obtained by reacting sulfydryl-containing amino acid with sodium alginate. Comprising the oral insulin liposome hydrogel prepared by the invention can be orally administered to a patient, and compared with injection, the oral insulin liposome hydrogel has the advantages that the pain of the patient is small, repeated administration is not needed, and the blood sugar control is stable; the hypoglycemic effect is good, the hypoglycemic duration is long, the effect is remarkable, and the bioavailability of insulin is high.
Owner:HEFEI UNIV OF TECH

Automatic feeding equipment for screws and flat gaskets of motor fixing pieces of automobile lifting window

The invention relates to automatic feeding equipment for screws and flat gaskets of motor fixing pieces of an automobile lifting window. The automatic feeding equipment comprises a vibration feeding mechanism, an arranging and feeding mechanism and an embedded part taking mechanism, wherein the vibration feeding mechanism and the arranging and feeding mechanism are used for sequentially feeding the screws and the flat gaskets respectively; the embedded part taking mechanism is used for transferring the screws and the flat gaskets into an injection molding machine; the vibration feeding mechanism comprises a flat gasket feeding assembly and a screw feeding assembly; the arranging and feeding mechanism comprises a flat gasket dislocation jacking assembly, a screw dislocation jacking assembly, a flat gasket clamping assembly used for grabbing the flat gaskets, a screw clamping assembly used for grabbing the screws, and an insert profiling transferring assembly used for arranging and placing the flat gaskets and the screws; and the embedded part taking mechanism comprises a moving module, a finished product part taking jig installed on the moving module, and an embedded material jig. The automatic feeding equipment for the screws and the flat gaskets of the motor fixing pieces of the automobile lifting window provided by the invention is used in cooperation with an injection molding machine, so that insert embedding is achieved, the automatic feeding equipment is suitable for products with specific specifications, the embedding and taking-out time is shortened, the production efficiency is improved, and the safety of workers is guaranteed.
Owner:苏州强世机器人有限公司

Composite material based on cyclodextrin-embedded salicylamide antifouling agent molecules and preparation method

The invention provides a composite material based on a cyclodextrin-embedded salicylamide antifouling agent molecules and a preparation method, and belongs to the technical fields of an antifouling agent controlled release material and preparation, aiming at the problem that an efficient control measure lacks in an application process of an antifouling agent, which results in short use period of an antifouling coating. Cyclodextrin and eco-friendly salicylamide antifouling molecules are adopted, a hydrophobic cavity is formed by cyclodextrin molecules, and van der Waals force, hydrophobic interaction, and size matching effect among host-guest molecules are taken as driving force, so that cyclodextrin embeds the antifouling molecules and a cyclodextrin-antifouling agent composite material is prepared. The composite material can release an antifouling agent into seawater in a controlled manner, prevents sudden release of the antifouling agent, and prolongs the antifouling valid period ofthe antifouling coating. The composite material is a controlled release antifouling material with great development potential and has bright application prospects.
Owner:725TH RES INST OF CHINA SHIPBUILDING INDAL CORP

Strip seal structure used for heat exchanger

The invention relates to a strip seal structure used for a heat exchanger. The two ends of a strip seal body extend and are bent to form bent parts correspondingly, and a groove is formed by each bent part and one side of the strip seal body. The other side of the strip seal body extends outwards to form a plurality of first flanges. A second flange is arranged in the position, between the first flanges, of the other side of the strip seal body. The strip seal structure used for the heat exchanger is simple in structure; and compared with existing strip seals for heat exchangers, the strip seal structure has the advantages of being small in size and occupied space, low in weight and small in material usage amount. Besides, as the multiple flanges are arranged on the outer side of the strip seal body, wind resistance can be effectively reduced, and the heat exchange efficiency is improved. As the inner side of the strip seal body is provided with the bent parts and the grooves, embedding-connection of a core body can be effectively achieved, the two ends of the core body are firmly installed in the grooves, and the stability of the core body is ensured.
Owner:WUXI JIANG YUAN ALUMINUM IND

Method for preparing molecule cage type starch

The utility model relates to a preparation method for starch, especially for molecule cage-like starch. The utility model solves the problems of cyclodextrin in unsuitability for the adsorption of macromolecules and small molecules, in the complex production process, in the high production cost, in the relative-poor postponing property as well as in the unstable and collapse-liable structure of multi-hole starch which leads to the inferiority to the original starch in terms of physical properties. Preparation method: 1. starch paste is prepared; 2. ball-milling starch paste; 3.drying, crushing; 4. molecules crosslinking; 5. graft, saponification; 6. settlement, vacuum strain. Molecule cage-like starch prepared in the utility model has the advantages of compact molecule shell structure, stable structure, internal loose, no collapse, and adjustable hole diameter in the molecule network. The molecule cage-like starch prepared in the utility model can absorb molecules of different sizes. The production process is simple, and the production cost is low, which is only 65 percent of the cyclodextrin production cost. The molecule cage-like starch prepared in the utility model is of good postponing property.
Owner:HARBIN INST OF TECH

Preparation method of premixed reinforced asphalt mixture

InactiveCN106477975ARoad performance improvementLarge labelFiberHardness
The invention discloses a preparation method of a premixed reinforced asphalt mixture. During the production process of the mixture, soft asphalt and mineral materials are premixed, so that the mixture is good in construction and usability, natural asphalt powder is used for re-mixing, so as to enhance the pavement performance, on one hand, the soft asphalt is high in grade and low in viscosity, the soft asphalt is uniformly mixed with aggregate at a relatively low temperature and the fluidity is good; on the other hand, hard natural asphalt containing a large amount of minerals is selected in the re-mixing process, so that the high-temperature performance, the anti-aging performance and the anti-stripping performance of the mixture can be remarkably improved, thus the pavement performance of the asphalt mixture is improved, and the service life is prolonged. In addition, the natural asphalt is high in hardness, is dispersed in the mixture after being remixed, and plays a role of filling, extruding and reinforcing ribs and cooperates with fibers to improve the low-temperature performance of the asphalt mixture; the premixed reinforced asphalt mixture preparation and construction process is simple, so that expensive additives such as warm mixing agents are avoided, and the road performance is improved at the same time.
Owner:CHANGAN UNIV

Method for preparing cochineal aluminum-free lake pigment by using protein, product and application of cochineal aluminum-free lake pigment

The invention discloses a method for preparing a cochineal aluminum-free lake pigment by using protein, a product and application of the cochineal aluminum-free lake pigment. The method comprises thefollowing steps: adding axinic acid into a buffer solution with a pH value of 3 to prepare a pigment solution, adding metal ions, and carrying out full stirring to obtain an axinic acid pigment solution; adding protein into the axinic acid solution, carrying out full and uniform mixing, adding polyphenol, carrying out uniform stirring, conducting centrifuging, taking a precipitate, freeze-drying the precipitate, and carrying out grinding to obtain the cochineal aluminum-free lake pigment. The method for preparing the cochineal aluminum-free lake pigment by using the protein is simple and convenient to operate; and the product does not contain aluminum, so the safety of the product is prevented from being doubted. According to the cochineal aluminum-free protein lake provided by the invention, the lake has a relatively good color generation effect in an alkaline dilute iron solution and an alkaline calcium solution, and shows a relatively good dyeing effect on dough, minced fillet and single cream.
Owner:JIANGNAN UNIV +1

Fixed joint of double-wall hollow pier column and steel bridge and construction method

The invention discloses a fixed joint of a double-wall hollow pier column and a steel bridge, which comprises a hollow section, a solid section, a reinforcing section and a conversion section, the hollow section, the solid section and the reinforcing section respectively comprise a composite material pipe, a steel pipe and a concrete layer between the composite material pipe and the steel pipe, and the conversion section comprises a steel pipe and stiffening ribs; the steel pipe and the stiffening ribs of the conversion section are used for being fixedly connected with a steel bridge; a steel inner partition plate is arranged between the steel pipe of the hollow section and the steel pipe of the solid section, a steel inner ring plate is arranged between the steel pipe of the solid section and the steel pipe of the reinforcing section, and a steel outer ring plate is arranged on the outer side of the junction of the steel pipe of the reinforcing section and the steel pipe of the conversion section. And one end of an anchor bolt is fastened on the steel outer ring plate, and the other end of the anchor bolt is anchored into the concrete layer between the composite pipe and the steel pipe of the reinforcing section. The invention further provides a corresponding construction method. The fixed joint solves the technical problem of fixed connection of the double-wall hollow pier column and the steel bridge, and has the advantages of being reliable in connection, gentle in rigidity transition, good in anti-seismic property and the like.
Owner:广州市城建规划设计院有限公司 +1

Nano microsphere loading with platinum-containing drugs, hydrogel coated with natural polymers and preparation method and application thereof

The invention provides a gelatin-polyacrylic acid composite nano microsphere of platinum-containing drugs, wherein, the surface of the nano microsphere is charged gelatin molecules, and the inner part is uncharged polyelectrolyte which is formed by the electrostatic interaction between the gelatin molecules and polyacrylic acid molecules; the platinum-containing drugs form a chemical coordinationeffect with the carboxyl group in the system to combine on the nano microsphere, wherein the mass of the platinum-containing drugs accounts for 5-45% of that of the composite nano microspheres, the content of gelatin accounts for 45-70% of the quality of the composite nano microspheres; the content of polyacrylic acid accounts for 10-25% of the quality of the composite nano microspheres, and the even grain diameter of the nano microspheres is 50-200 nanometers. The gelatin-polyacrylic acid composite nano microsphere loading with platinum-containing drugs can be used for being prepared into natural polymer hydrogel; the hydrogel not only possesses good biocompatibility and can be implanted in vivo and pasted on the position of the tumor in the process of surgical operation, but also can substantially improve the dosage of the platinum-containing drugs without adding the systematic toxic and side effect of drugs due to the characteristics of high drug-loading rate and slow-paced dual slow release of the hydrogel.
Owner:NANJING UNIV +1

Tool structure for measuring length of ring groove of plunger piston part

The invention relates to a tool structure for measuring the length of a ring groove of a plunger piston part. The tool structure comprises a chassis, wherein a support is fixedly connected with the chassis, a positioning mandrel penetrates the support and is located in the support, respectively sleeved by a first lining and a second lining and located between the first lining and the second lining, and a first spring is further arranged on the positioning mandrel. Steel balls are symmetrically arranged inside the positioning mandrel, and a second spring is connected between two steel balls. The tool structure is simple in structure and quick and convenient to measure, embedding connection of the ring groove of an inner ring of a plunger sleeve is achieved by utilizing the steel balls symmetrically arranged in the positioning mandrel, positioning is quick and convenient, a measurement standard of the plunger sleeve is effectively achieved by utilizing a blocking plate, measurement of a distance between the ring groove of the plunger sleeve and the end face is achieved, the time and labor are saved, the measurement efficiency is greatly improved, and the enterprise cost is saved.
Owner:无锡威孚马山油泵油嘴有限公司
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