65results about How to "Inhibition spikes" patented technology

Monomer addition methodology is provided to adjust monomer addition rates to a polymerization reactor. Advantages of the invention include control of bioabsorbable copolymer structure, improvement of monomer conversion, control of reaction temperature, and reduced reaction time. The overall result is an improved process and enhanced product performance. The technology is particularly useful in the copolymerization of monomers with different reactivity ratios, such as glycolide/lactide copolymers and glycolide/caprolactone copolymers. Monomer reactivity ratios and reaction kinetics are utilized to adjust monomer addition rates.

A power management integrated circuit includes pairs of high-side and low-side drivers, sensing circuitry, and a processor. The high-side and low-side drivers are used in combination with external discrete NFETs to drive multiple windings of a motor. The N-channel LDMOS transistor of each high-side driver has an associated isolation structure and a tracking and clamping circuit. If the voltage on a terminal of the integrated circuit pulses negative during a switching of current flow to the motor, then the isolation structure and tracking and clamping circuit clamps the voltage on the isolation structure and blocks current flow from the substrate to the drain. An associated ESD protection circuit allows the voltage on the terminal to pulse negative. As a result, a large surge of current that would otherwise flow through the high-side driver is blocked, and is conducted outside the integrated circuit through a body diode of an external NFET.

The invention generally relates to compositions and methods with covalently bound compounds, such as controlled substances covalently attached to a chemical moiety, and opioid antagonists or covalently bound opioid antagonists to enhance analgesic potency and/or attenuate one or more adverse effects of covalently bound compounds, including adverse side effect(s) in humans such as nausea, vomiting, dizziness, headache, sedation (somnolence), physical dependence or pruritis. This invention relates to compositions and methods for selectively enhancing the analgesic potency of a covalently bound compound and simultaneously attenuating anti-analgesia, hyperalgesia, hyperexcitability, physical dependence and/or tolerance effects associated with the administration of a covalently bound compound. The methods of the invention comprise administering to a subject an analgesic or sub-analgesic amount of a covalently bound compound and an amount of excitatory opioid receptor antagonist such as naltrexone or nalmefene effective to enhance the analgesic potency of a covalently bound compound and attenuate the anti-analgesia, hyperalgesia, hyperexcitability, physical dependence and/or tolerance effects of covalently bound compound. The invention also relates to the addition of covalently-bound opioid antagonists to the compositions containing covalently bound compounds such that if the compositions are subjected to manipulation by illicit chemists, the opioid antagonist is released effectively reducing or eliminating the euphoric effect of the covalently bound compounds.

The invention discloses polyimide aerogel having an infrared radiation resisting property and a preparation method thereof. The preparation method comprises the following steps: dehydrating through a reactor, carrying out a polymerization reaction to generate lyosol, preparing an infrared radiation blocker, aging the lyosol to obtain gel, and carrying out pressure infiltration, vacuum treatment and supercritical drying on the gel. The polyimide aerogel having the infrared radiation resisting property prepared by the preparation method disclosed by the invention is low in density, good flexibility and mechanical performance; the polyimide aerogel contains the nano-scale infrared radiation blocker which is uniformly distributed, and has properties of reflecting and absorbing infrared radiation at relatively high temperature, so that the aerogel is better than normal polyimide aerogel in heat insulating performance and is wider in using temperature range.

The disclosure relates to a method and apparatus for preventing extrusion or spiking of a metal atom from a metallization layer to other layers of a silicon wafer. In one embodiment, the method includes forming a silicon-on-ship device with a MEMS component on the substrate. The MEMS component may include one or more metal or metallic alloys. To prevent spiking from the MEMS component, the sides thereof can be coated with one ore more spacer or barrier layers. In one embodiment, oxygen plasma and thermal oxidation methods are used to deposit spacers. In another embodiment, an oxide layer is deposited over the wafer, covering the substrate and the MEMS component. Selective etching or anisotropic etching can be used to remove the oxide layer from certain regions of the MEMS and the substrate while covering the sidewalls. An amorphous silicon layer can then be deposited to cover the MEMS device.

The invention generally relates to compositions and methods with covalently bound compounds, such as controlled substances covalently attached to a chemical moiety, and opioid antagonists or covalently bound opioid antagonists to enhance analgesic potency and/or attenuate one or more adverse effects of covalently bound compounds, including adverse side effect(s) in humans such as nausea, vomiting, dizziness, headache, sedation (somnolence), physical dependence or pruritis. This invention relates to compositions and methods for selectively enhancing the analgesic potency of a covalently bound compound and simultaneously attenuating anti-analgesia, hyperalgesia, hyperexcitability, physical dependence and/or tolerance effects associated with the administration of a covalently bound compound. The methods of the invention comprise administering to a subject an analgesic or sub-analgesic amount of a covalently bound compound and an amount of excitatory opioid receptor antagonist such as naltrexone or nalmefene effective to enhance the analgesic potency of a covalently bound compound and attenuate the anti-analgesia, hyperalgesia, hyperexcitability, physical dependence and/or tolerance effects of covalently bound compound. The invention also relates to the addition of covalently-bound opioid antagonists to the compositions containing covalently bound compounds such that if the compositions are subjected to manipulation by illicit chemists, the opioid antagonist is released effectively reducing or eliminating the euphoric effect of the covalently bound compounds.

In a flip-flop circuit which includes an input section using a dynamic circuit and an output section using a static circuit and which captures data during a period of a pulse width shorter than a clock cycle, the number of transistors, circuit area and power consumption are reduced. In FIG. 1, an output signal of an inverter circuit (INV1) constituting a latch circuit (2) connected to the output terminal of an input section (1) is used as an input signal of a control section (3). Thus, a control signal output from the control section (3) to the input section (1) is stabilized, thereby suppressing unnecessary operation of circuit elements and reducing unnecessary power consumption. In addition, the configuration of the control section (3) is simplified. As a result, the number of transistors constituting the circuit and the circuit area can be reduced.

The invention provides methods for treating diabetes or obesity, as well as methods for inducing weight loss, preventing weight gain, or controlling weight in a patient in need thereof. The methods comprise administering to the patient at least one effective dose of a GLP-1 receptor agonist, or a regimen of GLP-1 receptor agonist comprising a plurality of substantially evenly spaced doses. The effective dose or regimen does not induce substantial nausea or appetite suppression in the patient.

A valve for use in aircraft comprises a body, a selective interrupter positioned inside the body for rotation therein, a flow arrangement between the selective interrupter and the body, a bonnet connected to the body and in contact with the selective interrupter, an arm extending through the bonnet and connected to the selective interrupter, and an actuator movably connected to the arm.

The invention discloses a multipath alternating current split-phase synchronous sampling method and circuit. An A-phase alternating current quantity channel is gated by multipath analog switches and AD conversion is controlled to be started; after completion of conversion, a B-phase alternating current quantity channel is gated, and an A-phase conversion result is read to the internal RAM of an MCU processor; after time of T/(N*3), AD conversion is started, a C-phase phase alternating current quantity channel is gated after completion of conversion, and a B-phase conversion result is read to the internal RAM of the MCU processor; after time of T/(N*3), AD conversion is started, the A-phase alternating current quantity channel is gated after completion of conversion, and a C-phase conversion result is read to the internal RAM of the MCU processor so that sampling of one point is completed by three-phase alternating current quantity; and after time of T/(N*3), the steps are repeated to perform N sampling and then cyclic sampling of three-phase alternating current signals is completed. 2/3 of the A/D conversion channel is saved, utilization rate of the A/D conversion channel is enhanced, hardware resources are saved and hardware cost is reduced.

The invention discloses a gas turbine control method and system. The phenomenon that a conventional PID controller easily makes sharp pulses appear in operation signals can be avoided without eliminating differential terms. The method includes the steps of obtaining state parameter benchmarks and actual state parameters of a gas turbine; transmitting the state parameter benchmarks as the reference input and the actual state parameters as the measurement value to a pre-established PID controller to obtain the fuel amount of the gas turbine, wherein the integer control of the PID controller is located in a forward channel, and the differential control of the PID controller is located in a feedback channel; controlling the working state of the gas turbine according to the fuel amount of the gas turbine.

The invention discloses a serial-connection type voltage adjusting circuit, which comprises a typical serial-connection voltage adjusting circuit body and a logic control circuit. The logic control circuit consists of a band-gap reference voltage input end and a ramp signal voltage input end, ramp signal voltage is gradually changed between zero and power voltage, an output end of the logic controller is connected with a positive input end of an error amplifier in the typical serial-connection voltage adjusting circuit body, when the ramp signal voltage is lower than band-gap reference voltage, voltage outputted by the logic control circuit is the ramp signal voltage, and when the ramp signal voltage is higher than the band-gap reference voltage, the voltage outputted by the logic control circuit is the band-gap reference voltage. By the aid of the serial-connection voltage adjusting circuit, peak impact can be avoided at the started moment.

The invention discloses a safety protection system of a block chain. The system comprises a signal sampling module and an enhanced noise reduction module, the signal sampling module samples node signals in a block chain system by using a signal sampler J1 with the model of DAM-3056AH, the enhanced noise reduction module uses a triode Q2, a triode Q3 and a capacitor C1 to form an enhancement circuit to stabilize signals, meanwhile, an operational amplifier AR2, a capacitor C2 and a capacitor C3 are used for forming a noise reduction circuit to reduce the signal-to-noise ratio, an adjustable resistor RW1, a diode D3, a diode D4 and a power supply+10V are used for providing compensation signals for a signal loop, meanwhile, an inductor L1 and capacitors C4-C6 are used for forming a frequencymodulation circuit to adjust the signal frequency, and finally, a signal emitter E1 is triggered to be sent to the safety protection system terminal of the block chain after in-phase amplification ofthe operational amplifier AR3, so that the safety protection system terminal of the block chain can analyze signals in time and judge whether the signals are lost or not, and alarm processing can be carried out in time.

An apparatus for transmitting an RF signal in a mobile communication terminal and a method for controlling the same. The apparatus is insensitive to temperature variation simultaneously with satisfying a specification of a mobile communication system, and reduces noise simultaneously with preventing output power from bounding. The apparatus includes a step-up converter for converting a signal to be transmitted into a signal of a transmission band; a reverse variable attenuator for performing high attenuation or low attenuation about an output signal of the step-up converter according to an attenuation control value; a transmission power processor for raising power of an output signal of the reverse variable attenuator to transmission power; and a controller for generating the attenuation control value used for performing high attenuation if the signal to be transmitted requires a low output power level, whereas performing low attenuation if the signal to be transmitted requires a high output power level.

The invention relates to a large combined cycle set before-separation automatic idle work reducing method and a control device. The method is characterized in that a distributed control system (DCS) is used for detecting the working state of a set, and by controlling exciting currents through an excitation system of the set, the fact that large combined cycle set before-separation idle work is reduced to a target value automatically is achieved. The structure is characterized in that the DCS, a detecting loop and a generator excitation controller AVR are included, the detecting loop is provided with a halt signal detecting end, a generator power utilization end voltage detecting end, an active power detecting end and an idle work detecting end, an output end of the detecting loop is connected with an input end of the DCS, an output end of the DCS is connected with a control input end of the generator excitation controller AVR, and an output end of the generator excitation controller AVR is connected with an input end of the excitation system of the generator set. The large combined cycle set before-separation automatic idle work reducing method and the control device have the advantages that voltage fluctuation caused by the fact that work conditions are changed suddenly, voltages at the generator end can jump because of separation, and a power grid gets rid of a large amount of idle work suddenly can be avoided.