The invention provides an EGCG preparation method, particularly relates to a preparation method for industrial production of high-purity EGCG and belongs to the field of separation and purification of
plant monomers. For solving the problem that at present, a process for preparing the EGCG based on an
organic solvent extraction method is complicated, adopts a large number of organic solvents in the production process and is not safe and environment-friendly enough, the EGCG preparation method comprises the following steps of
green tea smashing, vacuum high-temperature extraction with deionized water, inorganic
ceramic membrane
filtration, enrichment with macroporous adsorption resin,
reversed phase chromatography, vacuum concentration and freeze-
drying. The method only adopts water,
aqueous ethanol and other solvents in the whole preparation process of the process, the usage and
recovery amount of a large amount of organic solvents is decreased, the non-toxic, safe and simple process is achieved,
ceramic membrane, resin and reverse
chromatographic column filler are recyclable, the cost is greatly reduced, meanwhile the purity of the EGCG is improved, and the process is more suitable for large-scale EGCG production.