The invention relates to a pump valve coordinated multi-actuator electro-hydraulic control system. The pump valve coordinated multi-actuator electro-hydraulic control system comprises a prime motor, a transfer case, one or more hydraulic cylinders, distributed pump control units and a hydraulic cylinder displacement sensor, a centralized flow power compensation unit is additionally arranged for the distributed pump control units, and the centralized flow power compensation unit comprises a main hydraulic pump, a first overflow valve and an oil tank, a first pressure sensor, a pressure compensator, a control valve set, a bypass proportional valve and an oil supplementing energy accumulator. A valve core displacement sensor is additionally arranged on the pressure compensator. Each distributed pump control unit comprises a two-way variable pump/motor, a first oil supplementing one-way valve, a second oil supplementing one-way valve, a second overflow valve and a third overflow valve. By additionally arranging the centralized flow power compensation unit, the asymmetric flow of all the distributed pump control units is subjected to centralized compensation and power supplementation, various flow compensation auxiliary elements are not needed, a small-power pump control system drives and drags a high-power actuator, and the total installed power of the pump control multi-actuator system is remarkably reduced.