The invention discloses a bionic sleep multifunctional multi-layer structure mattress, which comprises a mattress main body and a mattress outer coating layer, wherein a bamboo fiber antibacterial carbon crystal cloth weaving layer, a magnet layer, a silver fiber anti-radiation layer, a latex pressure-retarding layer, a far infrared heat generation element layer, a negative ion cotton layer, a Chinese herb fiber layer and an elastic multi-layer coconut fiber layer are sequentially superposed from top to bottom to form the mattress main body, the mattress main body is coated with the mattress outer coating layer, the mattress outer coating layer and the bamboo fiber antibacterial carbon crystal cloth weaving layer are fixed through sewing, and the layers are adhered through natural latex. The bionic sleep multifunctional multi-layer structure mattress of the present invention has characteristics of water resistance, oil resistance, antibacterial property, negative ion release, good elasticity, toughness, durability, safety, comfort, health and environmental protection.