The invention provides a phenolic epoxy resin radiation protection coating, which comprises the following raw materials in parts by weight: 20-30 parts of phenolic epoxy resin, 10-15 parts of expanded graphite, 5-10 parts of carbon nanotubes, 1-30 parts of titanium dioxide 5 parts, 0.5-3 parts of hydroxypropyl methylcellulose, 8-14 parts of glass powder, 5-10 parts of talc powder, 8-12 parts of kaolin powder, 5-10 parts of perlite, 10-15 parts of wollastonite powder , 1-5 parts of dicyclopentenyloxyethyl acrylate and 20-30 parts of water. The present invention also provides a preparation method of the above-mentioned phenolic epoxy resin radiation protection coating. The components in the above-mentioned phenolic epoxy resin radiation-proof coating provided by the present invention cooperate with each other and complement each other, so that the coating has excellent anti-corrosion, radiation protection, antibacterial, flame-retardant, and anti-corrosion properties under the premise of maintaining good adhesion. High temperature, anti-cracking, anti-corrosion, resistance to alternating cold and heat, storage stability and other characteristics.