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30 results about "Injury mechanisms" patented technology

The mechanism of injury describes the particular circumstances that caused a given injury. Many medical professionals, including doctors and emergency medical technicians, are required to be familiar with a variety of circumstances that cause injury.

Combined load mode mechanical-electrical and thermal-magnetic coupling material performance in-situ test instrument and method

ActiveCN105628487ARich physical performance parametersRich performance parametersMaterial strength using tensile/compressive forcesMaterial strength using repeated/pulsating forcesCouplingPhysical field
The invention relates to a combined load mode mechanical-electrical and thermal-magnetic coupling material performance in-situ test instrument and method, and belongs to the field of precise scientific instruments. The test instrument comprises three parts: namely a combined load-multi-physical field loading test platform, an in-situ monitoring platform and a vibration-isolating base, wherein the vibration-isolating base is mainly used for supporting the combined load-multi-physical field loading test platform and the in-situ monitoring platform, and provides a positioning service for installation of the platforms and effective vibration isolating treatment for various precise driving loading elements, detecting elements and in-situ monitoring elements; the in-situ monitoring platform realizes real-time dynamic and in-situ monitoring on micro deformation, injury mechanism, microstructure changes and property evolution of a material sample under the combined load condition by precisely adjusting the position and posture of various monitoring modules. The combined load mode mechanical-electrical and thermal-magnetic coupling material performance in-situ test instrument has the following advantages: the structure is miniaturized and lightened in weight, and the instrument body can be placed in an optionally equipped vacuum cavity, so that testing environments like low pressure, vacuum and inert gases can be provided for the material sample to be tested, and the practicability is high.
Owner:JILIN UNIV

Cross-scale micro-nano-scale in-situ composite load mechanical performance testing platform

The invention relates to a cross-scale micro nanometer grade in-situ composite load mechanical property testing platform, belonging to electromechanics. The cross-scale micro nanometer grade in-situ composite load mechanical property testing platform is composed of a precision drive and transmission unit, a signal detection and control unit and a clamping, connecting and supporting unit, wherein,in the precision drive and transmission unit, a DC servo motor provides power output, and a two-stage worm and gear mechanism with large reduction ratio and a precision ball screw mechanism transmit power; the signal detection and control unit is composed of a precision displacement sensor, a precision pull pressure sensor and a coder in coaxial rigid connection with the DC servo motor; and the clamping, connecting and supporting unit comprises a clamper component for locating and mounting a standard test specimen, and the like. The cross-scale micro nanometer grade in-situ composite load mechanical property testing platform can be compatible with imaging instruments, and performs a cross-scale in-situ micro nanometer composite load test on a macroscopic test specimen through observation via the imaging instruments, so as to perform in-situ monitoring on processes of microscopic deformation, injury and fracture of materials, so that a new testing method for revealing the mechanical properties and the injury mechanism of the materials at the micro nanometer grade is provided.
Owner:JILIN UNIV

High-temperature double-axis synchronous drawing mechanical property testing instrument and method

The invention relates to a high-temperature double-axis synchronous drawing mechanical property testing instrument and method and belongs to the field of precision scientific instruments. According to the device provided by the invention, three bevel gears, which are mutually orthogonal, are driven by one alternating current servo motor, so that equal-speed synchronous drawing of X axis and Y axis is realized, and non-equal-speed synchronous drawing of the X axis and the Y axis is realized; and single-axis drawing along an X-axis direction also can be realized. A high-temperature heating furnace is provided with an optical window and can be integrated with an optical microscope; and dynamic in-situ monitoring of micro-mechanical behaviors and an injury mechanism in a material temperature-varying drawing testing process is realized. By adopting a novel innovative structure, the difficulty that synchronous loading is difficult to realize through double-axis drawing is effectively overcome; meanwhile, the high-temperature double-axis synchronous drawing mechanical property testing instrument also has functions of the non-equal-speed synchronous drawing, the single-axis drawing and the like, and has the advantages of compact structure, small occupied area, convenience for integration and control and good application prospect; and the high-temperature double-axis synchronous drawing mechanical property testing instrument has very important meanings on testing researches on dynamic properties when the material bears a complicated stress state under a high-temperature condition.
Owner:JILIN UNIV

Measuring device and measuring method for film photo-thermal property

The invention discloses a measuring device and measuring method for film photo-thermal property. Based on the original surface thermal lens technology, the modulation frequency of pumping light beams is changed, so that the amplitude of detecting signals and the relationship of phase signals changed along with the frequency can be obtained. The relationship and the calculated result of the theoretical model are compared, and then some important information of the inner part of the film can be obtained. In the invention, not only can the absorption rate of the film be measured, but also the thermal conduction rate of a single-layer film and the deep indexing of some strong absorption impurities can be measured, so that the comprehensive evaluation on the photo-thermal property of the film can be conducted, and greater auxiliary action on the aspects of optimizing film coating process, seeking injury mechanisms and the like can be achieved.
Owner:SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI

Corrosion experiment and injury evaluation methods of engineering material under wind sand environment

The invention relates to an experiment method and an injury evaluation method of an engineering material and particularly relates to corrosion experiment and injury evaluation methods of the engineering material under a wind sand environment. An experiment system and a method for operating the experiment system are included; the experiment system comprises a wind sand environment simulation system and an erosion room; the injury evaluation method of the engineering material based on a wind sand environment experiment system comprises a weight-loss grading method and a weight-loss rate evaluation method, wherein weight loss is the difference of masses of a test piece before and after an abrasion test, namely deltam=m1-m2; the weight-loss rate is the ratio of the difference of the masses of the test piece before and after the abrasion test to the total mass of sand used in the time period, namely alpha=(deltam / ms*t)*100%=(m1-m2 / ms*t)*100%. The experiment system provided by the invention has the advantages that an actual wind and sand corrosion environment can be really simulated, erosion mechanical parameters are easy to accurately control, a testing period is short and the research cost is low; the experiment and injury evaluation methods explore an erosion abrasion rule and an injury mechanism of the engineering material from macroscopic and microcosmic aspects.
Owner:INNER MONGOLIA UNIV OF TECH

Shoe, a patch and a method for preventing ankle injuries

A shoe for preventing ankle injuries comprises a sole with a ground-engaging surface, and lateral and medial edges associated with respective lateral and medial connecting portions interconnecting and extending between the ground-engaging surface and the lateral and medial edges. At least one of the connecting portions defines a surface area of reduced friction provided, e.g., in the form of retrofitted patches, which are circumferentially surrounded by adjacent surface areas having a relatively high coefficient of friction. Friction is differentiated in different areas of those parts of the shoe which are implicated in injury mechanisms, and injuries may thus be prevented in the recovery phase after injury, and primary prophylaxis may be achieved. The area of reduced friction reduces the ability of the wearer's foot to rotate relative to ground when the load of the wearer's body is shifted towards or lands near the edge of the shoe.
Owner:SPRAINO IP APS

Road traffic accident information deep processing method

The invention relates to a road traffic accident information deep processing method. The method includes the following steps that a data collection module collects accident site survey information, accident vehicle damage information and casualty information and transmits the information to a processing module; the processing module carries out data pre-processing on the collected information to obtain the corresponding collision relation of parties in an accident; the processing module carries out accident reconstruction simulation, evaluation on the injury level of the wound, injury mechanism analysis of the wound in the process of the accident, reason analysis of the accident, vehicle safety evaluation and the like according to the data obtained after pre-processing, and corresponding evaluation and analysis data are obtained; ultimately, the data are output to a database to be stored in a report mode to serve as bases of road traffic safety analysis and new vehicle model development. Compared with the prior art, the road traffic accident information deep processing method has the advantages of being comprehensive, scientific, high in reliability and operability and the like.
Owner:TONGJI UNIV +1

Application of donkey-hide gelatins to preparation of medicament or healthcare product for treating respiratory injury caused by fine air particulate matters

The invention discloses application of donkey-hide gelatins to preparation of a medicament or healthcare product for treating respiratory injury caused by fine air particulate matters, and belongs to the field of novel medicinal uses of donkey-hide gelatins. SD rats continuously inhale the fine air particulate matters for 8 weeks, and are given by gavage with different dosages of donkey-hide gelatin solutions for medicinal intervention at the same time of contamination, researches on an injury mechanism caused by toxicity and a protection mechanism of the donkey-hide gelatins for respiratory injury caused by the fine air particulate patterns are made from weights, organ coefficients and pulmonary functions in combination with the aspects of the hematology, blood biochemical index measurement, respiratory functions, histopathological examination, oxidative damage and the like, and experimental results show that the donkey-hide gelatins can be used for effectively reducing the content of malondialdehyde and the number of pulmonary alveolar phagocytes and increasing the content of glutathione peroxidase, have an exact improvement effect on rat pulmonary function and pulmonary pathological changes caused by the fine air particulate matters and can be applied to preparation of the medicament or healthcare product for treating respiratory injury caused by the fine air particulate matters.
Owner:SHAN DONG DONG E E JIAO

Coal ash soil composite material for highway subgrade and preparation method thereof

The invention relates to a fly ash and soil composite material used in highway roadbed and is characterized in that the material consists of fly ash, soil and polypropylene fiber; the technique is simple and reliable to ensure that the fly ash and soil composite material has good frost resistance property; the unconfined compressive strength of the fly ash and soil which is doped with the polypropylene fiber is 1.26 to 1.74 times higher than the unconfined compressive strength of pure fly ash and soil. According to the characteristics of roadbed freezing injury mechanism and structural style in seasonal frozen areas, the fly ash and soil composite material of the invention adopts novel materials which have the advantages of good resistance to freezing and thawing, high strength, low cost and environmental protection as the roadbed filler, which not only has theoretical guidance meaning, but also has direct practical meaning for solving engineering problems.
Owner:JILIN UNIV

Construction method of in-vitro model for simulating mesenchymal stem cell transplantation

The invention discloses a construction method of an in-vitro model for simulating mesenchymal stem cell transplantation, which comprises the following steps of: (1) selecting in-vitro neonatal rat cortical neurons; (2) selecting in-vitro rat mesenchymal stem cells; (3) pre-processing the in-vitro rat mesenchymal stem cells, and inoculating in the neonatal rat cortical neurons for co-culture; and (4) after the co-culture, treating the rat mesenchymal stem cells and the neonatal rat cortical neurons by a light microscope, a fluorescence microscope, an atomic force microscope and a scanning electron microscope; and determining an in-vitro model for simulating mesenchymal stem cell transplantation and a growth tendency, an interaction and formation of a synapsis-like structure between the cortical neurons and the mesenchymal stem cells on an ultrastructure. The construction method disclosed by the invention provides a simplified in-vitro model for the mesenchymal stem cell transplantation; meanwhile, the synapsis-like structure formed in the model provides an in-vitro evidence of a structure integration mechanism for the mesenchymal stem cell injury mechanism.
Owner:姜晓丹 +1

Injury experiment device for simulating brain deceleration injury in traffic accident

The invention discloses an injury experiment device for simulating a brain deceleration injury in a traffic accident. The device comprises a rack and an acceleration device, a rotating driving device,an experiment box, a simulation track and a deceleration device. The experiment box is arranged on the simulation track. The acceleration device and the deceleration device are arranged at the starting line and the finishing line of the simulation track respectively, the acceleration device is used for driving the experiment box to move on the simulation track, the acceleration device is used fordecelerating the experiment box, and the experiment box is used for fixing an animal needed by an experiment. According to the injury experiment device for simulating the brain deceleration injury inthe traffic accident, the deceleration injury mechanism process can be independently simulated, the diffusible axis cylinder injury causing mechanism process can also be simulated, the brain deceleration injury causing process with the diffusible axis cylinder injury in the traffic accident can be effectively simulated, the repeatability is high, and the experiment result is accurate.
Owner:中国人民解放军陆军特色医学中心

Spring type animal beating device and method

The invention discloses a spring type animal beating device. The spring type animal beating device comprises a base, a fixator and an indication panel and beating parts, wherein the base is connected with the beating part through a screw, the indication panel is composed of a perpendicular panel and a slide panel, and the slide panel is additionally provided with a protractor and transversely slides on the perpendicular panel. The beating parts include a beating rod, a spring and a beating guide rail, and the beating rod moves along the beating guide rail. The invention provides a spring type animal beating method. The spring type small animal beating device can mark different beating forces with angle degrees, by replacing different springs and beating rods, beating of small and medium animals can be realized, injury classification animal beating models can be easily manufactured, and the spring type animal beating type is applicable to researches of biomechanics, injury mechanism and pathology.
Owner:吴敬杰

Drug for relieving body injury caused by chronic alcoholic poisoning

The invention provides a drug for relieving body injury caused by chronic alcoholic poisoning. The drug comprises an effective ingredient of AOAA (aminooxyacetic acid). Learning and memory ability evaluation is performed on chronic alcoholic poisoned rats and normal rats by use of a Y-type electric maze by establishing a rate chronic alcoholic poisoning model. Experimental results prove that compared with normal control groups, the chronic alcoholic poisoning model group of rats has remarkably reduced learning and memory ability. After AOAA intervention is given, the training times required for rats of a remedy group to learn spatial discrimination are reduced, and difference has statistical significance. Accordingly, AOAA can relieve memory deterioration caused by the chronic alcoholic poisoned rats, improves the learning memory ability and provides a scientific basis for research of chronic alcoholic poisoning injury mechanism and treatment by AOAA.
Owner:XINXIANG MEDICAL UNIV

Method for determining carbon steel corrosion rate in coexisting environment of naphthenic acid and sulfur

InactiveCN101887006AFailure probability analysis is scientific and reasonableWeather/light/corrosion resistanceSulfurLikelihood analysis
The invention discloses a method for determining the carbon steel corrosion rate in a coexisting environment of naphthenic acid and sulfur. The method is characterized in that in the coexisting environment of naphthenic acid and sulfur, carbon steel equipment has two dominant injury mechanisms which are respectively a naphthenic acid dominant mechanism and a sulfur dominant mechanism, and the two mechanisms simultaneously have the inhibiting effect on of the sulfur on the naphthenic acid; and the total corrosion rate of the carbon steel equipment is the summation of the corrosion rates of the two dominant injury mechanisms and the corrosion rate of the naphthenic acid under the inhibiting effect of the sulfur. In the method, the factors such as the interaction of the dominant mechanisms, the influence of secondary mechanisms on the dominant mechanisms, and the like are considered while determining the corrosion rate, and related methods in API581 are improved so that the probability analysis of equipment failures in risk evaluation are more scientific, reasonable and practical.
Owner:HEFEI GENERAL MACHINERY RES INST

Shoe, a patch and a method for preventing ankle injuries

A shoe for preventing ankle injuries comprises a sole with a ground-engaging surface, and lateral and medial edges associated with respective lateral and medial connecting portions interconnecting and extending between the ground-engaging surface and the lateral and medial edges. At least one of the connecting portions defines a surface area of reduced friction provided, e.g., in the form of retrofitted patches, which are circumferentially surrounded by adjacent surface areas having a relatively high coefficient of friction. Friction is differentiated in different areas of those parts of the shoe which are implicated in injury mechanisms, and injuries may thus be prevented in the recovery phase after injury, and primary prophylaxis may be achieved. The area of reduced friction reduces the ability of the wearer's foot to rotate relative to ground when the load of the wearer's body is shifted towards or lands near the edge of the shoe.
Owner:SPRAINO IP APS

Visual Colles fracture and reduction model device

PendingCN114822199AFix fixitySolve the problem that the manual reset process cannot be displayedEducational modelsPlastic materialsDeformity
The invention relates to the technical field of medical teaching fracture model devices, and discloses a visual Colles fracture and reduction model device which comprises a medical upper limb forearm model, a visual structure, a simulated ligament wrist joint and a distal radius fracture structure. According to the appearance, the distal radius of the medical upper limb forearm model with the silver fork-like deformity is of a visual structure made of a transparent soft skin-imitating material, and the surface of the model is made of an openable yellow invisible soft skin-imitating material; the model is internally provided with a simulated ligament wrist joint and distal radius fracture structure, and is made of a white hard plastic material; after operation reduction, fracture is reproduced according to an injury mechanism, and reutilization is realized. The visual Colles fracture model device disclosed by the invention has high simulation appearance and clinical touch hand feeling, and completely meets clinical training requirements; through the application of the model device in teaching, the problems that a model is fixed and cannot display a technique resetting process and a resetting effect are effectively solved; and the clinical work quality and efficiency are improved.
Owner:宁德市闽东医院

Construction method of residual root model of rat brachial plexus injury and evaluation method of residual root function

The invention discloses a construction method of residual root model of rat brachial plexus injury and an evaluation method of a residual root function of the rat brachial plexus injury. The construction method and the evaluation method mentioned above include the steps of preparing a rat nerve residual root model, conducting gross anatomical observation, conducting spinal cord extraction and histological evaluation, and conducting spinal cord extraction and histological evaluation, wherein the preparation of the rat nerve residual root model includes the steps of making a right-sided arc incision through a dorsal approach, cutting skin, shallow and deep muscles in order, using a small pull hook to pull a right shoulder blade to one side and expose entire right brachial plexus, continuingnerve root division towards the proximal end under a microscope until five nerve roots are completely exposed, simulating a clinical injury mechanism, using microscopic hemostats to fix proximal nerveroots and corresponding surrounding muscle tissues one by one, using hemostats to pull the nerve roots at a far end, and forming residual roots of the nerve roots after pulling; the spinal cord extraction and histological evaluation includes the steps of detecting expression levels of neurofilament protein NF-200 and myelin scattering protein S-100 in the residual roots, axon diameter, the numberof axons and myelin sheath thickness.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Safe and reliable cutting machine anti-injury mechanism

The invention provides a safe and reliable cutting machine anti-injury mechanism, and belongs to the technical field of building machinery, the safe and reliable cutting machine anti-injury mechanism comprises a base, stand columns are fixedly mounted at the top of the base, the stand columns are opposite in pairs, rotating rods are rotatably mounted on the opposite sides of the stand columns, and two supporting rods are fixedly mounted at the top of each rotating rod; a cutting machine is fixedly installed on the opposite sides of the two supporting rods, a driving rod is fixedly installed on the left sides of the supporting rods, a shielding plate is fixedly installed on the top of the rotating rod, the driving rod is connected with the shielding plate, and the shielding plate and the cutting machine are connected together through the driving rod. The baffle plate covers the cutting machine all the time, sparks generated in the cutting process are prevented from splashing, and as the sparks generated in the cutting process of the cutting machine face the left side in the tangential direction of the cutter, the effect of effectively preventing dust from splashing is achieved.
Owner:扬州金信益电动工具有限公司

Cross-scale micro nanometer grade in-situ composite load mechanical property testing platform

The invention relates to a cross-scale micro nanometer grade in-situ composite load mechanical property testing platform, belonging to electromechanics. The cross-scale micro nanometer grade in-situ composite load mechanical property testing platform is composed of a precision drive and transmission unit, a signal detection and control unit and a clamping, connecting and supporting unit, wherein,in the precision drive and transmission unit, a DC servo motor provides power output, and a two-stage worm and gear mechanism with large reduction ratio and a precision ball screw mechanism transmit power; the signal detection and control unit is composed of a precision displacement sensor, a precision pull pressure sensor and a coder in coaxial rigid connection with the DC servo motor; and the clamping, connecting and supporting unit comprises a clamper component for locating and mounting a standard test specimen, and the like. The cross-scale micro nanometer grade in-situ composite load mechanical property testing platform can be compatible with imaging instruments, and performs a cross-scale in-situ micro nanometer composite load test on a macroscopic test specimen through observation via the imaging instruments, so as to perform in-situ monitoring on processes of microscopic deformation, injury and fracture of materials, so that a new testing method for revealing the mechanical properties and the injury mechanism of the materials at the micro nanometer grade is provided.
Owner:JILIN UNIV

Finite element model of 30-degree trunk angle national sign six-year-old child passenger and construction method and application thereof

PendingCN113643816AOvercome the difficulty of angle adjustment and the shortcomings of single sitting posture of child occupantsOvercome the shortcomings of a single sitting postureMedical simulationHealth-index calculationPhysical medicine and rehabilitationElement model
The invention discloses a method for constructing a finite element model of a 30-degree trunk angle national sign six-year-old child passenger. The method comprises the steps: calculating the kinematics parameters and stress-strain distribution conditions of a six-year-old child passenger in a specific sitting posture through units and nodes with mechanical properties, so as to judge the injury condition of the six-year-old child passenger; and a basis is provided for studying the injury mechanism of the six-year-old child passengers in different sitting postures and the protection effect of a child restraint system. According to the building method and application of the finite element model of the six-year-old child passenger with the 30-degree trunk angle, the postures of the six-year-old child passenger are enriched, and technical support is provided for further research on the injury mechanism of the six-year-old child passenger and the applicability of a safety restraint system.
Owner:TIANJIN UNIV OF SCI & TECH

Measuring device and measuring method for film photo-thermal property

The invention discloses a measuring device and measuring method for film photo-thermal property. Based on the original surface thermal lens technology, the modulation frequency of pumping light beams is changed, so that the amplitude of detecting signals and the relationship of phase signals changed along with the frequency can be obtained. The relationship and the calculated result of the theoretical model are compared, and then some important information of the inner part of the film can be obtained. In the invention, not only can the absorption rate of the film be measured, but also the thermal conduction rate of a single-layer film and the deep indexing of some strong absorption impurities can be measured, so that the comprehensive evaluation on the photo-thermal property of the film can be conducted, and greater auxiliary action on the aspects of optimizing film coating process, seeking injury mechanisms and the like can be achieved.
Owner:SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI

Multi-knee-bending-angle knee joint finite element model and preparation method thereof

The invention relates to a multi-knee-bending-angle knee joint finite element model and a preparation method thereof, and belongs to the field of joint anatomy. The model reversely reconstructs the main structure of the knee joint according to MRI data of healthy adults. The model collects and reconstructs a healthy knee joint three-dimensional model when actively bending the knee at 0 degree, 15 degrees, 30 degrees, 45 degrees, 60 degrees, 75 degrees, 90 degrees, 105 degrees and 120 degrees. The model comprises sixteen parts including a femur, a tibia, a fibula, a patella, a femur cartilage, a tibial plateau medial cartilage, a tibial plateau lateral cartilage, a patella cartilage, a medial meniscus, a lateral meniscus, an anterior cruciate ligament, a posterior cruciate ligament, a medial collateral ligament, a lateral collateral ligament, a quadriceps femoris tendon and a patellar tendon. The multi-knee-bending-angle knee joint finite element model is based on a real human knee joint, is complete in structure, is suitable for anatomical learning of the knee joint, and provides a unwonted real knee joint bending and stretching prediction model for simulating the actual condition of the knee joint, researching an injury mechanism, formulating a preoperative plan, clinical teaching and the like.
Owner:FIRST AFFILIATED HOSPITAL OF KUNMING MEDICAL UNIV

Simulation experimental system for disaster environment of fire, explosion and poison

The invention belongs to the field of disaster environment simulation system, and particularly relates to a simulation experimental system for disaster environment of fire, explosion and poison, the simulation experimental system comprises an explosive shock wave generating device arranged at one end of a pipeline, a fire high-temperature generation device and a poisonous gas / particles environmentgeneration device which are arranged on the middle of the pipeline, and pipeline where the fire high-temperature generation device and the poisonous gas / particles environment generation device arranged is taken as a testing section of the simulation experiment system. The advantages of the simulation experimental system for disaster environment of fire, explosion and poison are that: a compound disaster experiment environment is provided, by providing with the explosive shock wave generating device, the fire high-temperature generation device and the poisonous gas / particles environment generation device on the pipeline, disaster environments with explosive shock waves, poison substances and high temperature can be simulated, guidance of human body injury mechanism and individual protection technical requirement in the disaster environment of fire, explosion and poison, and selection of appropriate emergency equipment for hazardous chemical practitioners are provided, and finally a purpose of protecting life safety of people is achieved.
Owner:HEFEI INST FOR PUBLIC SAFETY RES TSINGHUA UNIV +1

Pathogen infection injury mechanism analysis method and device thereof

An embodiment of the invention provides a pathogen infection injury mechanism analysis method and a device thereof, wherein the method and the device belong to the field of gene data processing. The method comprises the steps of acquiring full-genome expression data after silencing of a plurality of genes; obtaining a gene expression order row which corresponds with the full-genome expression data; acquiring the full-genome expression spectrum data after infection of a plurality of different pathogens; constructing an imprinting gene set which is infected by the pathogen based on the full-genome expression spectrum data; acquiring enrichment scores of the gene expression order sequence and the imprinting gene set; and determining the pathogen infection injury mechanism based on the enrichment scores, thereby combining mass various cross-platform transcriptome big data, realizing no requirement for pathogen culturing from the beginning or cell infection or large-scale experiment, further reducing development cost and shortening detecting period. Furthermore experiment errors are reduced so that higher accuracy in analyzing the pathogen infection injury mechanism is realized.
Owner:ACADEMY OF MILITARY MEDICAL SCI

Adjustable macaque spinal cord injury method

PendingCN111658216AReduce fatalityEasy to operateSurgical veterinaryDiseaseTraumatic spinal cord injury
The invention relates to an adjustable macaque spinal cord injury method. An elastic saccule is transplanted in a target spinal cord segment of the vertebral canal of a macaque, a water injecting opening in the far end of the saccule is buried at a neighbouring subcutaneous position; normal saline of different volumes is injected in the saccule to manufacture macaque spinal cord injury models of different injury degrees. A method of using the saccule for pressing the vertebral canal of the macaque is adopted to construct the macaque spinal cord injury model of which the injury degree, the injury time interval and the injury position can be adjusted and controlled, so that the model construction effect is lasting, the injury is progressive, the injury degree behavior is visualized, trauma to the macaque is small, the lethality is low, and the method can be used for simulating and researching pathology injury mechanisms and treatment strategies of lesion of spinal cord trauma, intramedullary tumor / intradural-extramedullary tumor, intervertebral disk hernia, spinal cord congenital malformation, spinal cord infection and the like, and has important significance on preclinical test of various diseases.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI
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