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1 results about "Ornithine aspartate" patented technology
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L-Ornithine L-aspartate (LOLA), a stable salt of ornithine and aspartic acid, has been used in the treatment of cirrhosis. Weast, Robert C., ed. (1981). Weber AL, Miller SL (1981). "Reasons for the occurrence of the twenty coded protein amino acids" (PDF). "Ornithine Biosynthesis".
Use of ornithine L-aspartate in the preparation of a drug for treating systemic senescence
This invention discloses the application of ornithine aspartate in the preparation of drugs for treating systemic aging. By applying ornithine aspartate to regulate the systemic aging process, this invention can effectively improve hepatocyte dysfunction, restore cell proliferation activity, alleviate cell cycle arrest, and reduce the abnormal expression of aging-related genes and proteins in multiple tissues and organs such as the liver, kidneys, heart, muscles, and fat, thereby delaying the aging process. This technical solution can significantly improve the structural disorder and lipid deposition in aging liver tissue, reduce serum transaminase levels, improve liver function, reduce insulin resistance, inhibit the overexpression of SASP-related inflammatory factors, and maintain metabolic homeostasis. Furthermore, it effectively improves aging phenotypes in multiple tissues and organs. Therefore, this invention has significant technical effects and application potential in delaying systemic aging and improving motor function and metabolic abnormalities.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH